CAS 91599-81-4 · Piperidine · 3 functional traits · cGMP compliant · Ships from USA in 2-3 days
(R)-(-)-1-Benzyl-3-hydroxypiperidine >95% (CAS Number: 91599-81-4) is a piperidine-containing compound — one of the most drug-prevalent saturated N-heterocycles featuring a Piperidine ring with defined stereochemistry. ChemContract Research supplies this moderate-complexity compound in high purity from our Huntington Beach, California facility, ensuring consistent quality and reliable domestic delivery throughout the United States.
The piperidine ring is the most common nitrogen heterocycle in FDA-approved drugs, appearing in over 70 marketed pharmaceuticals across CNS, cardiovascular, and oncology indications. Hydroxyl groups are critical pharmacophores — they serve as hydrogen-bond donors and acceptors, influencing drug–target binding, aqueous solubility, and metabolic susceptibility. Chirality matters profoundly in drug action — enantiomers can differ by orders of magnitude in potency, and FDA guidelines increasingly require single-enantiomer development.
Primary applications include cns drug scaffold (present in donepezil, methylphenidate, fentanyl class) and mitsunobu reaction substrate for stereospecific inversion at chiral centers. This compound serves researchers and manufacturers across the pharmaceutical, cns therapeutics, medicinal chemistry sectors. Whether you require (R)-(-)-1-Benzyl-3-hydroxypiperidine >95% for early-stage research, process development, or commercial-scale production, ChemContract Research offers flexible ordering from milligram to multi-kilogram quantities with custom synthesis options and full batch documentation including Certificates of Analysis (CoA) and Safety Data Sheets.
How (R)-(-)-1-Benzyl-3-hydroxypiperidine >95% is used across pharmaceutical and cns therapeutics sectors
CNS drug scaffold (present in donepezil, methylphenidate, fentanyl class)
Mitsunobu reaction substrate for stereospecific inversion at chiral centers
Enantiopure building block for single-enantiomer drug development
Conformationally-restricted amine for receptor binding optimization
Oxidation to aldehydes (Swern, Dess–Martin) or ketones for downstream chemistry
Chiral resolution standard or chiral HPLC reference compound
Detailed specifications for this piperidine, including purity, molecular weight, and analytical data are available upon request. Every batch from ChemContract Research includes:
Handle with standard precautions. Piperidine and some derivatives have strong amine odors. Use a fume hood. Handle with standard precautions. Some alcohols are flammable. Use adequate ventilation and appropriate PPE. Handle with standard precautions. Ensure proper labeling of stereochemical identity to prevent mix-ups.
Store at room temperature in a well-sealed container. Some N-unsubstituted piperidines are volatile. Store at room temperature in a tightly sealed container away from heat sources and oxidizers. Store under recommended conditions. Some chiral compounds may racemize at elevated temperatures or in the presence of base.
Piperidine scaffolds like (R)-(-)-1-Benzyl-3-hydroxypiperidine >95% are found in 70+ marketed drugs. We stock common analogs for rapid medicinal chemistry screening.
Every batch of (R)-(-)-1-Benzyl-3-hydroxypiperidine >95% is produced under cGMP conditions with full CoA documentation, HPLC purity verification, and lot traceability.
Ship from our Huntington Beach, CA facility with 2-3 business day domestic delivery. No import delays, no customs fees, no tariff surprises.
Need a specific grade, quantity, or derivative of (R)-(-)-1-Benzyl-3-hydroxypiperidine >95%? Our team of PhD chemists can develop custom synthesis solutions for your exact requirements.
Common questions about (R)-(-)-1-Benzyl-3-hydroxypiperidine >95%
(R)-(-)-1-Benzyl-3-hydroxypiperidine >95% is a piperidine-containing compound — one of the most drug-prevalent saturated N-heterocycles used primarily in the pharmaceutical and cns therapeutics industries. Key applications include cns drug scaffold (present in donepezil, methylphenidate, fentanyl class) and mitsunobu reaction substrate for stereospecific inversion at chiral centers.
ChemContract Research is a trusted USA-based supplier of (R)-(-)-1-Benzyl-3-hydroxypiperidine >95%. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.
ChemContract Research supplies (R)-(-)-1-Benzyl-3-hydroxypiperidine >95% in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.
Yes. ChemContract Research offers custom synthesis services for (R)-(-)-1-Benzyl-3-hydroxypiperidine >95% from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.
ChemContract Research supplies (R)-(-)-1-Benzyl-3-hydroxypiperidine >95% with verified enantiomeric or diastereomeric purity as documented in our Certificate of Analysis (CoA). Chiral HPLC analysis is standard for stereodefined compounds. We can provide material with ≥98% ee/de for demanding applications. Contact us for specific optical purity requirements.
The Piperidine ring system(s) in (R)-(-)-1-Benzyl-3-hydroxypiperidine >95% is a privileged structure in medicinal chemistry, appearing in numerous FDA-approved drugs. This scaffold is commonly used in kinase inhibitor design, GPCR modulator development, and lead optimization programs. ChemContract supplies this building block for early-stage discovery through process-scale manufacturing.
Store at room temperature in a well-sealed container. Some N-unsubstituted piperidines are volatile. Store at room temperature in a tightly sealed container away from heat sources and oxidizers. Store under recommended conditions. Some chiral compounds may racemize at elevated temperatures or in the presence of base. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.
The CAS Registry Number for (R)-(-)-1-Benzyl-3-hydroxypiperidine >95% is 91599-81-4. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.
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