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4-(Diphenyl methoxy)-1-piperidine HCl

CAS 132-18-3 · Piperidine · 2 functional traits · cGMP compliant · Ships from USA in 2-3 days

Piperidine

4-(Diphenyl methoxy)-1-piperidine HCl

Piperidines PharmaceuticalCNS TherapeuticsMedicinal ChemistryResearchFormulationAnalytical Chemistry
CAS Number 132-18-3
Category Piperidine · Hydrochloride Salt
Origin USA
Compliance cGMP

Questions? Contact our chemistry team:

chemistry@chem-contract.com | +1 (714) 732-8549
In stock — typically ships within 2-3 business days

About 4-(Diphenyl methoxy)-1-piperidine HCl

4-(Diphenyl methoxy)-1-piperidine HCl (CAS Number: 132-18-3) is a piperidine-containing compound — one of the most drug-prevalent saturated N-heterocycles featuring Piperidine, Benzene ring systems. ChemContract Research supplies this moderate-complexity compound in high purity from our Huntington Beach, California facility, ensuring consistent quality and reliable domestic delivery throughout the United States. Supplied as the hydrochloride salt form for enhanced stability and handling.

The piperidine ring is the most common nitrogen heterocycle in FDA-approved drugs, appearing in over 70 marketed pharmaceuticals across CNS, cardiovascular, and oncology indications. Hydrochloride is the most common salt form for basic drug substances — approximately half of all salt-form drugs on the market are HCl salts, valued for their crystallinity and aqueous solubility.

Primary applications include cns drug scaffold (present in donepezil, methylphenidate, fentanyl class) and improved handling characteristics versus the free base form. This compound serves researchers and manufacturers across the pharmaceutical, cns therapeutics, medicinal chemistry sectors. Whether you require 4-(Diphenyl methoxy)-1-piperidine HCl for early-stage research, process development, or commercial-scale production, ChemContract Research offers flexible ordering from milligram to multi-kilogram quantities with custom synthesis options and full batch documentation including Certificates of Analysis (CoA) and Safety Data Sheets.

Ring Systems: PiperidineBenzene
Functional Groups: Alkoxy (–OR)
Salt Form: Hydrochloride

Piperidine Applications & Target Industries

How 4-(Diphenyl methoxy)-1-piperidine HCl is used across pharmaceutical and cns therapeutics sectors

01

CNS drug scaffold (present in donepezil, methylphenidate, fentanyl class)

02

Improved handling characteristics versus the free base form

03

Conformationally-restricted amine for receptor binding optimization

04

Direct formulation excipient in oral solid dosage forms

05

Spirocyclic and fused ring system construction for 3D drug design

06

Crystalline form screening for polymorph and salt studies

Target Industries: PharmaceuticalCNS TherapeuticsMedicinal ChemistryResearchFormulationAnalytical Chemistry

4-(Diphenyl methoxy)-1-piperidine HCl Specifications

Detailed specifications for this piperidine, including purity, molecular weight, and analytical data are available upon request. Every batch from ChemContract Research includes:

  • Certificate of Analysis (CoA) with purity verification
  • HPLC, NMR, and/or mass spectrometry characterization data
  • Material Safety Data Sheet (MSDS/SDS)
  • Batch-specific documentation and lot traceability
  • Custom analytical testing available on request
Request Full Specifications

Quick Reference

Compound Name 4-(Diphenyl methoxy)-1-piperidine HCl
Type Piperidine
Category Piperidine · Hydrochloride Salt
Purity ≥95% (custom grades available)
Salt Form Hydrochloride
Complexity Moderate (1 functional groups, 2 rings)
Compliance cGMP
Packaging mg to kg scale

Storage & Handling for Piperidines

Handling Guidelines

Handle with standard precautions. Piperidine and some derivatives have strong amine odors. Use a fume hood. Handle with standard precautions. Hydrochloride salts are generally more stable than free bases.

Storage Conditions

Store at room temperature in a well-sealed container. Some N-unsubstituted piperidines are volatile. Store at room temperature in a tightly sealed container. Protect from humidity.

Why Buy 4-(Diphenyl methoxy)-1-piperidine HCl From ChemContract?

Quality Assured

Every batch of 4-(Diphenyl methoxy)-1-piperidine HCl is produced under cGMP conditions with full CoA documentation, HPLC purity verification, and lot traceability.

Fast USA Shipping

Ship from our Huntington Beach, CA facility with 2-3 business day domestic delivery. No import delays, no customs fees, no tariff surprises.

Custom Synthesis

Need a specific grade, quantity, or derivative of 4-(Diphenyl methoxy)-1-piperidine HCl? Our team of PhD chemists can develop custom synthesis solutions for your exact requirements.

Frequently Asked

Common questions about 4-(Diphenyl methoxy)-1-piperidine HCl

What is 4-(Diphenyl methoxy)-1-piperidine HCl used for? +

4-(Diphenyl methoxy)-1-piperidine HCl is a piperidine-containing compound — one of the most drug-prevalent saturated N-heterocycles used primarily in the pharmaceutical and cns therapeutics industries. Key applications include cns drug scaffold (present in donepezil, methylphenidate, fentanyl class) and improved handling characteristics versus the free base form.

Where can I buy 4-(Diphenyl methoxy)-1-piperidine HCl in the USA? +

ChemContract Research is a trusted USA-based supplier of 4-(Diphenyl methoxy)-1-piperidine HCl. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.

What purity levels are available for 4-(Diphenyl methoxy)-1-piperidine HCl? +

ChemContract Research supplies 4-(Diphenyl methoxy)-1-piperidine HCl in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.

Can ChemContract synthesize 4-(Diphenyl methoxy)-1-piperidine HCl in custom quantities? +

Yes. ChemContract Research offers custom synthesis services for 4-(Diphenyl methoxy)-1-piperidine HCl from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.

What drug discovery applications use 4-(Diphenyl methoxy)-1-piperidine HCl? +

The Piperidine ring system(s) in 4-(Diphenyl methoxy)-1-piperidine HCl is a privileged structure in medicinal chemistry, appearing in numerous FDA-approved drugs. This scaffold is commonly used in kinase inhibitor design, GPCR modulator development, and lead optimization programs. ChemContract supplies this building block for early-stage discovery through process-scale manufacturing.

Can I get 4-(Diphenyl methoxy)-1-piperidine HCl in a different salt form or as the free base? +

Yes. ChemContract Research can supply 4-(Diphenyl methoxy)-1-piperidine HCl as the free base or convert it to alternative salt forms including hydrochloride, mesylate, tosylate, fumarate, or other pharmaceutically acceptable counter-ions. Salt form selection impacts crystallinity, stability, and solubility — our chemistry team can advise on optimal salt selection for your application. Currently supplied as the Hydrochloride form.

How should I store 4-(Diphenyl methoxy)-1-piperidine HCl? +

Store at room temperature in a well-sealed container. Some N-unsubstituted piperidines are volatile. Store at room temperature in a tightly sealed container. Protect from humidity. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.

What is the CAS number of 4-(Diphenyl methoxy)-1-piperidine HCl? +

The CAS Registry Number for 4-(Diphenyl methoxy)-1-piperidine HCl is 132-18-3. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.

Chemical analysis laboratory with HPLC instruments for purity and impurity testing Custom chemical synthesis reaction setup for pharmaceutical intermediate production

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