Frequently Asked
Common questions about [S]-1-Boc-3-bromopyrrolidine >95%
What is [S]-1-Boc-3-bromopyrrolidine >95% used for?
[S]-1-Boc-3-bromopyrrolidine >95% is a bromo-substituted intermediate prized for its reactivity in metal-catalyzed coupling used primarily in the pharmaceutical and fine chemical industries. Key applications include grignard reagent preparation via magnesium insertion into c–br bond and solid-phase peptide synthesis (spps) with orthogonal boc/fmoc strategies.
Where can I buy [S]-1-Boc-3-bromopyrrolidine >95% in the USA?
ChemContract Research is a trusted USA-based supplier of [S]-1-Boc-3-bromopyrrolidine >95%. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.
What purity levels are available for [S]-1-Boc-3-bromopyrrolidine >95%?
ChemContract Research supplies [S]-1-Boc-3-bromopyrrolidine >95% in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.
Can ChemContract synthesize [S]-1-Boc-3-bromopyrrolidine >95% in custom quantities?
Yes. ChemContract Research offers custom synthesis services for [S]-1-Boc-3-bromopyrrolidine >95% from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.
How do I remove the Boc group from [S]-1-Boc-3-bromopyrrolidine >95%?
The Boc protecting group in [S]-1-Boc-3-bromopyrrolidine >95% is cleanly removed by treatment with trifluoroacetic acid (TFA, 20–50% in DCM) at room temperature, typically within 30–60 minutes. Alternative conditions include HCl in dioxane (4M) or trimethylsilyl triflate with 2,6-lutidine. The Boc group is stable to base, hydrogenation, and many nucleophilic conditions, making it orthogonal to Fmoc and Cbz groups.
What coupling reactions can I run with [S]-1-Boc-3-bromopyrrolidine >95%?
As a brominated compound, [S]-1-Boc-3-bromopyrrolidine >95% is an excellent substrate for palladium-catalyzed cross-coupling reactions including Suzuki, Heck, Negishi, Sonogashira, and Buchwald–Hartwig amination. It can also be used for Grignard reagent preparation, metal–halogen exchange with organolithium reagents, and nucleophilic substitution reactions.
How should I store [S]-1-Boc-3-bromopyrrolidine >95%?
Store at room temperature in a tightly sealed, light-resistant container. Some bromo compounds require refrigeration. Store at room temperature in a sealed container. Stable under neutral and basic conditions; avoid strong acids during storage. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.
What is the CAS number of [S]-1-Boc-3-bromopyrrolidine >95%?
The CAS Registry Number for [S]-1-Boc-3-bromopyrrolidine >95% is 569660-89-5. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.
