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Pyrrolidine-3-carboxylic acid hydrochloride 95%

CAS 953079-94-2 · Carboxylic Acid · 2 functional traits · cGMP compliant · Ships from USA in 2-3 days

Carboxylic Acid

Pyrrolidine-3-carboxylic acid hydrochloride 95%

Heterocycles PharmaceuticalPolymerFine ChemicalAgrochemicalFormulationAnalytical Chemistry
CAS Number 953079-94-2
Category Carboxylic Acid · Hydrochloride Salt
Origin USA
Compliance cGMP

Questions? Contact our chemistry team:

chemistry@chem-contract.com | +1 (714) 732-8549
In stock — typically ships within 2-3 business days

About Pyrrolidine-3-carboxylic acid hydrochloride 95%

Pyrrolidine-3-carboxylic acid hydrochloride 95% (CAS Number: 953079-94-2) is a carboxylic acid that participates in diverse condensation and coupling reactions featuring a Pyrrolidine ring. ChemContract Research supplies this moderate-complexity compound in high purity from our Huntington Beach, California facility, ensuring consistent quality and reliable domestic delivery throughout the United States. Supplied as the hydrochloride salt form for enhanced stability and handling.

Carboxylic acids are among the most synthetically versatile functional groups — they can be converted to amides, esters, acid chlorides, anhydrides, alcohols, and aldehydes in a single step. Hydrochloride is the most common salt form for basic drug substances — approximately half of all salt-form drugs on the market are HCl salts, valued for their crystallinity and aqueous solubility.

Primary applications include amide bond formation via edc/hobt or hatu coupling in peptide synthesis and improved handling characteristics versus the free base form. This compound serves researchers and manufacturers across the pharmaceutical, polymer, fine chemical sectors. Whether you require Pyrrolidine-3-carboxylic acid hydrochloride 95% for early-stage research, process development, or commercial-scale production, ChemContract Research offers flexible ordering from milligram to multi-kilogram quantities with custom synthesis options and full batch documentation including Certificates of Analysis (CoA) and Safety Data Sheets.

Ring Systems: Pyrrolidine
Functional Groups: Carboxylic acid (–COOH)Chlorine (C–Cl)
Salt Form: Hydrochloride

Carboxylic Acid Applications & Target Industries

How Pyrrolidine-3-carboxylic acid hydrochloride 95% is used across pharmaceutical and polymer sectors

01

Amide bond formation via EDC/HOBt or HATU coupling in peptide synthesis

02

Improved handling characteristics versus the free base form

03

Salt formation with amines to improve drug crystallinity and stability

04

Direct formulation excipient in oral solid dosage forms

05

Ester prodrug synthesis for enhanced oral bioavailability

06

Crystalline form screening for polymorph and salt studies

Target Industries: PharmaceuticalPolymerFine ChemicalAgrochemicalFormulationAnalytical Chemistry

Pyrrolidine-3-carboxylic acid hydrochloride 95% Specifications

Detailed specifications for this carboxylic acid, including purity, molecular weight, and analytical data are available upon request. Every batch from ChemContract Research includes:

  • Certificate of Analysis (CoA) with purity verification
  • HPLC, NMR, and/or mass spectrometry characterization data
  • Material Safety Data Sheet (MSDS/SDS)
  • Batch-specific documentation and lot traceability
  • Custom analytical testing available on request
Request Full Specifications

Quick Reference

Compound Name Pyrrolidine-3-carboxylic acid hydrochloride 95%
Type Carboxylic Acid
Category Carboxylic Acid · Hydrochloride Salt
Purity ≥95% (custom grades available)
Salt Form Hydrochloride
Complexity Moderate (2 functional groups, 1 ring)
Compliance cGMP
Packaging mg to kg scale

Storage & Handling for Carboxylic Acids

Handling Guidelines

Acids may be corrosive or irritating. Handle with chemical-resistant gloves and eye protection. Use a fume hood for volatile acids. Handle with standard precautions. Hydrochloride salts are generally more stable than free bases.

Storage Conditions

Store at room temperature in a tightly sealed container. Protect from moisture and strong bases. Store at room temperature in a tightly sealed container. Protect from humidity.

Why Buy Pyrrolidine-3-carboxylic acid hydrochloride 95% From ChemContract?

Quality Assured

Every batch of Pyrrolidine-3-carboxylic acid hydrochloride 95% is produced under cGMP conditions with full CoA documentation, HPLC purity verification, and lot traceability.

Fast USA Shipping

Ship from our Huntington Beach, CA facility with 2-3 business day domestic delivery. No import delays, no customs fees, no tariff surprises.

Custom Synthesis

Need a specific grade, quantity, or derivative of Pyrrolidine-3-carboxylic acid hydrochloride 95%? Our team of PhD chemists can develop custom synthesis solutions for your exact requirements.

Frequently Asked

Common questions about Pyrrolidine-3-carboxylic acid hydrochloride 95%

What is Pyrrolidine-3-carboxylic acid hydrochloride 95% used for? +

Pyrrolidine-3-carboxylic acid hydrochloride 95% is a carboxylic acid that participates in diverse condensation and coupling reactions used primarily in the pharmaceutical and polymer industries. Key applications include amide bond formation via edc/hobt or hatu coupling in peptide synthesis and improved handling characteristics versus the free base form.

Where can I buy Pyrrolidine-3-carboxylic acid hydrochloride 95% in the USA? +

ChemContract Research is a trusted USA-based supplier of Pyrrolidine-3-carboxylic acid hydrochloride 95%. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.

What purity levels are available for Pyrrolidine-3-carboxylic acid hydrochloride 95%? +

ChemContract Research supplies Pyrrolidine-3-carboxylic acid hydrochloride 95% in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.

Can ChemContract synthesize Pyrrolidine-3-carboxylic acid hydrochloride 95% in custom quantities? +

Yes. ChemContract Research offers custom synthesis services for Pyrrolidine-3-carboxylic acid hydrochloride 95% from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.

Can I get Pyrrolidine-3-carboxylic acid hydrochloride 95% in a different salt form or as the free base? +

Yes. ChemContract Research can supply Pyrrolidine-3-carboxylic acid hydrochloride 95% as the free base or convert it to alternative salt forms including hydrochloride, mesylate, tosylate, fumarate, or other pharmaceutically acceptable counter-ions. Salt form selection impacts crystallinity, stability, and solubility — our chemistry team can advise on optimal salt selection for your application. Currently supplied as the Hydrochloride form.

What coupling reagents work best with Pyrrolidine-3-carboxylic acid hydrochloride 95%? +

For amide bond formation from the carboxylic acid in Pyrrolidine-3-carboxylic acid hydrochloride 95%, HATU/DIPEA is recommended for peptide coupling (high yield, low epimerization). EDC/HOBt is a cost-effective alternative for non-peptide amides. T3P (propylphosphonic acid anhydride) offers excellent atom economy with easy workup. For ester formation, DCC/DMAP (Steglich conditions) or Mitsunobu conditions are standard.

How should I store Pyrrolidine-3-carboxylic acid hydrochloride 95%? +

Store at room temperature in a tightly sealed container. Protect from moisture and strong bases. Store at room temperature in a tightly sealed container. Protect from humidity. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.

What is the CAS number of Pyrrolidine-3-carboxylic acid hydrochloride 95%? +

The CAS Registry Number for Pyrrolidine-3-carboxylic acid hydrochloride 95% is 953079-94-2. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.

Chemical analysis laboratory with HPLC instruments for purity and impurity testing Custom chemical synthesis reaction setup for pharmaceutical intermediate production

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