Frequently Asked
Common questions about Potassium (bromomethyl)trifluoroborate
What is Potassium (bromomethyl)trifluoroborate used for?
Potassium (bromomethyl)trifluoroborate is a fluorine-containing building block with enhanced metabolic stability used primarily in the pharmaceutical and diagnostic imaging industries. Key applications include metabolic blocking strategy — fluorine substitution to improve drug half-life and grignard reagent preparation via magnesium insertion into c–br bond.
Where can I buy Potassium (bromomethyl)trifluoroborate in the USA?
ChemContract Research is a trusted USA-based supplier of Potassium (bromomethyl)trifluoroborate. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.
What purity levels are available for Potassium (bromomethyl)trifluoroborate?
ChemContract Research supplies Potassium (bromomethyl)trifluoroborate in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.
Can ChemContract synthesize Potassium (bromomethyl)trifluoroborate in custom quantities?
Yes. ChemContract Research offers custom synthesis services for Potassium (bromomethyl)trifluoroborate from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.
What coupling reactions can I run with Potassium (bromomethyl)trifluoroborate?
As a brominated compound, Potassium (bromomethyl)trifluoroborate is an excellent substrate for palladium-catalyzed cross-coupling reactions including Suzuki, Heck, Negishi, Sonogashira, and Buchwald–Hartwig amination. It can also be used for Grignard reagent preparation, metal–halogen exchange with organolithium reagents, and nucleophilic substitution reactions.
Why is fluorine important in Potassium (bromomethyl)trifluoroborate?
The fluorine atom(s) in Potassium (bromomethyl)trifluoroborate confer several advantages in drug design: increased metabolic stability due to the strong C–F bond (485 kJ/mol), enhanced lipophilicity for improved membrane permeability, and potential for favorable electrostatic interactions with biological targets. These properties make fluorinated compounds like Potassium (bromomethyl)trifluoroborate valuable in pharmaceutical development.
How should I store Potassium (bromomethyl)trifluoroborate?
Store at recommended temperature in a tightly sealed container. Protect from moisture, heat, and incompatible materials. Store at room temperature in a tightly sealed, light-resistant container. Some bromo compounds require refrigeration. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.
What is the CAS number of Potassium (bromomethyl)trifluoroborate?
The CAS Registry Number for Potassium (bromomethyl)trifluoroborate is 888711-44-2. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.
