CAS 105751-19-7 · Piperidine · 2 functional traits · cGMP compliant · Ships from USA in 2-3 days
N-Fmoc-piperidine-2-carboxylic acid >96% (CAS Number: 105751-19-7) is a piperidine-containing compound — one of the most drug-prevalent saturated N-heterocycles featuring a Piperidine ring. ChemContract Research supplies this moderate-complexity compound in high purity from our Huntington Beach, California facility, ensuring consistent quality and reliable domestic delivery throughout the United States.
The piperidine ring is the most common nitrogen heterocycle in FDA-approved drugs, appearing in over 70 marketed pharmaceuticals across CNS, cardiovascular, and oncology indications. Carboxylic acids are among the most synthetically versatile functional groups — they can be converted to amides, esters, acid chlorides, anhydrides, alcohols, and aldehydes in a single step.
Primary applications include cns drug scaffold (present in donepezil, methylphenidate, fentanyl class) and amide bond formation via edc/hobt or hatu coupling in peptide synthesis. This compound serves researchers and manufacturers across the pharmaceutical, cns therapeutics, medicinal chemistry sectors. Whether you require N-Fmoc-piperidine-2-carboxylic acid >96% for early-stage research, process development, or commercial-scale production, ChemContract Research offers flexible ordering from milligram to multi-kilogram quantities with custom synthesis options and full batch documentation including Certificates of Analysis (CoA) and Safety Data Sheets.
How N-Fmoc-piperidine-2-carboxylic acid >96% is used across pharmaceutical and cns therapeutics sectors
CNS drug scaffold (present in donepezil, methylphenidate, fentanyl class)
Amide bond formation via EDC/HOBt or HATU coupling in peptide synthesis
Conformationally-restricted amine for receptor binding optimization
Salt formation with amines to improve drug crystallinity and stability
Spirocyclic and fused ring system construction for 3D drug design
Ester prodrug synthesis for enhanced oral bioavailability
Detailed specifications for this piperidine, including purity, molecular weight, and analytical data are available upon request. Every batch from ChemContract Research includes:
Handle with standard precautions. Piperidine and some derivatives have strong amine odors. Use a fume hood. Acids may be corrosive or irritating. Handle with chemical-resistant gloves and eye protection. Use a fume hood for volatile acids.
Store at room temperature in a well-sealed container. Some N-unsubstituted piperidines are volatile. Store at room temperature in a tightly sealed container. Protect from moisture and strong bases.
Piperidine scaffolds like N-Fmoc-piperidine-2-carboxylic acid >96% are found in 70+ marketed drugs. We stock common analogs for rapid medicinal chemistry screening.
Every batch of N-Fmoc-piperidine-2-carboxylic acid >96% is produced under cGMP conditions with full CoA documentation, HPLC purity verification, and lot traceability.
Ship from our Huntington Beach, CA facility with 2-3 business day domestic delivery. No import delays, no customs fees, no tariff surprises.
Need a specific grade, quantity, or derivative of N-Fmoc-piperidine-2-carboxylic acid >96%? Our team of PhD chemists can develop custom synthesis solutions for your exact requirements.
Common questions about N-Fmoc-piperidine-2-carboxylic acid >96%
N-Fmoc-piperidine-2-carboxylic acid >96% is a piperidine-containing compound — one of the most drug-prevalent saturated N-heterocycles used primarily in the pharmaceutical and cns therapeutics industries. Key applications include cns drug scaffold (present in donepezil, methylphenidate, fentanyl class) and amide bond formation via edc/hobt or hatu coupling in peptide synthesis.
ChemContract Research is a trusted USA-based supplier of N-Fmoc-piperidine-2-carboxylic acid >96%. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.
ChemContract Research supplies N-Fmoc-piperidine-2-carboxylic acid >96% in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.
Yes. ChemContract Research offers custom synthesis services for N-Fmoc-piperidine-2-carboxylic acid >96% from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.
The Piperidine ring system(s) in N-Fmoc-piperidine-2-carboxylic acid >96% is a privileged structure in medicinal chemistry, appearing in numerous FDA-approved drugs. This scaffold is commonly used in kinase inhibitor design, GPCR modulator development, and lead optimization programs. ChemContract supplies this building block for early-stage discovery through process-scale manufacturing.
For amide bond formation from the carboxylic acid in N-Fmoc-piperidine-2-carboxylic acid >96%, HATU/DIPEA is recommended for peptide coupling (high yield, low epimerization). EDC/HOBt is a cost-effective alternative for non-peptide amides. T3P (propylphosphonic acid anhydride) offers excellent atom economy with easy workup. For ester formation, DCC/DMAP (Steglich conditions) or Mitsunobu conditions are standard.
Store at room temperature in a well-sealed container. Some N-unsubstituted piperidines are volatile. Store at room temperature in a tightly sealed container. Protect from moisture and strong bases. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.
The CAS Registry Number for N-Fmoc-piperidine-2-carboxylic acid >96% is 105751-19-7. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.
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