Search 7,000+ Chemicals

Start typing to search our catalog

Methyl4-iodo-2-methoxybenzoate

Iodinated Compound · 2 functional traits · cGMP compliant · Ships from USA in 2-3 days

Iodinated Compound

Methyl4-iodo-2-methoxybenzoate

Halogenated PharmaceuticalNuclear MedicineFine ChemicalResearchPolymerGreen Chemistry
Category Iodinated Compound · Ester
Origin USA
Compliance cGMP

Questions? Contact our chemistry team:

chemistry@chem-contract.com | +1 (714) 732-8549
In stock — typically ships within 2-3 business days

About Methyl4-iodo-2-methoxybenzoate

Methyl4-iodo-2-methoxybenzoate is an iodo-substituted compound offering high reactivity in metal-mediated transformations. ChemContract Research supplies this moderate-complexity compound in high purity from our Huntington Beach, California facility, ensuring consistent quality and reliable domestic delivery throughout the United States.

The C–I bond is the weakest carbon–halogen bond, which translates to the highest reactivity in oxidative addition — making aryl iodides the first-choice substrate for challenging cross-coupling reactions. Ester hydrolysis by cellular esterases is the most commonly exploited prodrug activation mechanism — enabling drugs that cannot cross biological membranes as free acids.

Primary applications include sonogashira and heck coupling with the lowest activation barrier among aryl halides and prodrug development to mask carboxylic acids and improve membrane permeability. This compound serves researchers and manufacturers across the pharmaceutical, nuclear medicine, fine chemical sectors. Whether you require Methyl4-iodo-2-methoxybenzoate for early-stage research, process development, or commercial-scale production, ChemContract Research offers flexible ordering from milligram to multi-kilogram quantities with custom synthesis options and full batch documentation including Certificates of Analysis (CoA) and Safety Data Sheets.

Functional Groups: Ester (–COOR)Iodine (C–I)Alkoxy (–OR)

Iodinated Compound Applications & Target Industries

How Methyl4-iodo-2-methoxybenzoate is used across pharmaceutical and nuclear medicine sectors

01

Sonogashira and Heck coupling with the lowest activation barrier among aryl halides

02

Prodrug development to mask carboxylic acids and improve membrane permeability

03

Radioiodination precursor for SPECT and PET diagnostic imaging

04

Protecting group for hydroxyl functionalities (acetate, benzoate)

05

Metal–halogen exchange with n-BuLi for directed metalation strategies

06

Ring-opening polymerization monomer for biodegradable polymers

Target Industries: PharmaceuticalNuclear MedicineFine ChemicalResearchPolymerGreen Chemistry

Methyl4-iodo-2-methoxybenzoate Specifications

Detailed specifications for this iodinated compound, including purity, molecular weight, and analytical data are available upon request. Every batch from ChemContract Research includes:

  • Certificate of Analysis (CoA) with purity verification
  • HPLC, NMR, and/or mass spectrometry characterization data
  • Material Safety Data Sheet (MSDS/SDS)
  • Batch-specific documentation and lot traceability
  • Custom analytical testing available on request
Request Full Specifications

Quick Reference

Compound Name Methyl4-iodo-2-methoxybenzoate
Type Iodinated Compound
Category Iodinated Compound · Ester
Purity ≥95% (custom grades available)
Complexity Moderate (3 functional groups, 0 rings)
Compliance cGMP
Packaging mg to kg scale

Storage & Handling for Iodinated Compounds

Handling Guidelines

Iodo compounds may be light-sensitive and can stain skin. Handle in a fume hood and protect from light during use. Some esters are volatile and flammable. Handle in a well-ventilated area. Keep away from ignition sources.

Storage Conditions

Store refrigerated (2–8 °C) in a light-resistant, tightly sealed container under inert atmosphere to prevent degradation. Store at room temperature in a tightly sealed container away from heat and open flame.

Why Buy Methyl4-iodo-2-methoxybenzoate From ChemContract?

Quality Assured

Every batch of Methyl4-iodo-2-methoxybenzoate is produced under cGMP conditions with full CoA documentation, HPLC purity verification, and lot traceability.

Fast USA Shipping

Ship from our Huntington Beach, CA facility with 2-3 business day domestic delivery. No import delays, no customs fees, no tariff surprises.

Custom Synthesis

Need a specific grade, quantity, or derivative of Methyl4-iodo-2-methoxybenzoate? Our team of PhD chemists can develop custom synthesis solutions for your exact requirements.

Frequently Asked

Common questions about Methyl4-iodo-2-methoxybenzoate

What is Methyl4-iodo-2-methoxybenzoate used for? +

Methyl4-iodo-2-methoxybenzoate is an iodo-substituted compound offering high reactivity in metal-mediated transformations used primarily in the pharmaceutical and nuclear medicine industries. Key applications include sonogashira and heck coupling with the lowest activation barrier among aryl halides and prodrug development to mask carboxylic acids and improve membrane permeability.

Where can I buy Methyl4-iodo-2-methoxybenzoate in the USA? +

ChemContract Research is a trusted USA-based supplier of Methyl4-iodo-2-methoxybenzoate. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.

What purity levels are available for Methyl4-iodo-2-methoxybenzoate? +

ChemContract Research supplies Methyl4-iodo-2-methoxybenzoate in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.

Can ChemContract synthesize Methyl4-iodo-2-methoxybenzoate in custom quantities? +

Yes. ChemContract Research offers custom synthesis services for Methyl4-iodo-2-methoxybenzoate from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.

What coupling reactions can I run with Methyl4-iodo-2-methoxybenzoate? +

As a iodinated compound, Methyl4-iodo-2-methoxybenzoate is an excellent substrate for palladium-catalyzed cross-coupling reactions including Suzuki, Heck, Negishi, Sonogashira, and Buchwald–Hartwig amination. It can also be used for Grignard reagent preparation, metal–halogen exchange with organolithium reagents, and nucleophilic substitution reactions.

How should I store Methyl4-iodo-2-methoxybenzoate? +

Store refrigerated (2–8 °C) in a light-resistant, tightly sealed container under inert atmosphere to prevent degradation. Store at room temperature in a tightly sealed container away from heat and open flame. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.

Chemical analysis laboratory with HPLC instruments for purity and impurity testing Custom chemical synthesis reaction setup for pharmaceutical intermediate production

Get Methyl4-iodo-2-methoxybenzoate Delivered This Week

Get competitive pricing, custom quantities, and fast USA delivery. Our chemistry team is standing by to provide specifications, CoA documentation, and a tailored quote for your project.

Or call us directly: +1 (714) 732-8549

ChemContract

Let's Build
Your Molecule

From discovery to commercial scale — our 500+ scientists are ready to accelerate your project.

24-Hour ResponseFast turnaround guaranteed
60+ FacilitiesGlobal R&D network
cGMP CompliantFDA-ready manufacturing

Request a Quote

Tell us about your compound and we'll send a detailed quote within 24 hours.

Contact Information
Chemical Specifications
ChemContract
Mon-Fri 8AM-5PM PT

Hi there! How can we help you today?