Iodinated Compound · 2 functional traits · cGMP compliant · Ships from USA in 2-3 days
Methyl4-iodo-2-methoxybenzoate is an iodo-substituted compound offering high reactivity in metal-mediated transformations. ChemContract Research supplies this moderate-complexity compound in high purity from our Huntington Beach, California facility, ensuring consistent quality and reliable domestic delivery throughout the United States.
The C–I bond is the weakest carbon–halogen bond, which translates to the highest reactivity in oxidative addition — making aryl iodides the first-choice substrate for challenging cross-coupling reactions. Ester hydrolysis by cellular esterases is the most commonly exploited prodrug activation mechanism — enabling drugs that cannot cross biological membranes as free acids.
Primary applications include sonogashira and heck coupling with the lowest activation barrier among aryl halides and prodrug development to mask carboxylic acids and improve membrane permeability. This compound serves researchers and manufacturers across the pharmaceutical, nuclear medicine, fine chemical sectors. Whether you require Methyl4-iodo-2-methoxybenzoate for early-stage research, process development, or commercial-scale production, ChemContract Research offers flexible ordering from milligram to multi-kilogram quantities with custom synthesis options and full batch documentation including Certificates of Analysis (CoA) and Safety Data Sheets.
How Methyl4-iodo-2-methoxybenzoate is used across pharmaceutical and nuclear medicine sectors
Sonogashira and Heck coupling with the lowest activation barrier among aryl halides
Prodrug development to mask carboxylic acids and improve membrane permeability
Radioiodination precursor for SPECT and PET diagnostic imaging
Protecting group for hydroxyl functionalities (acetate, benzoate)
Metal–halogen exchange with n-BuLi for directed metalation strategies
Ring-opening polymerization monomer for biodegradable polymers
Detailed specifications for this iodinated compound, including purity, molecular weight, and analytical data are available upon request. Every batch from ChemContract Research includes:
Iodo compounds may be light-sensitive and can stain skin. Handle in a fume hood and protect from light during use. Some esters are volatile and flammable. Handle in a well-ventilated area. Keep away from ignition sources.
Store refrigerated (2–8 °C) in a light-resistant, tightly sealed container under inert atmosphere to prevent degradation. Store at room temperature in a tightly sealed container away from heat and open flame.
Every batch of Methyl4-iodo-2-methoxybenzoate is produced under cGMP conditions with full CoA documentation, HPLC purity verification, and lot traceability.
Ship from our Huntington Beach, CA facility with 2-3 business day domestic delivery. No import delays, no customs fees, no tariff surprises.
Need a specific grade, quantity, or derivative of Methyl4-iodo-2-methoxybenzoate? Our team of PhD chemists can develop custom synthesis solutions for your exact requirements.
Common questions about Methyl4-iodo-2-methoxybenzoate
Methyl4-iodo-2-methoxybenzoate is an iodo-substituted compound offering high reactivity in metal-mediated transformations used primarily in the pharmaceutical and nuclear medicine industries. Key applications include sonogashira and heck coupling with the lowest activation barrier among aryl halides and prodrug development to mask carboxylic acids and improve membrane permeability.
ChemContract Research is a trusted USA-based supplier of Methyl4-iodo-2-methoxybenzoate. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.
ChemContract Research supplies Methyl4-iodo-2-methoxybenzoate in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.
Yes. ChemContract Research offers custom synthesis services for Methyl4-iodo-2-methoxybenzoate from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.
As a iodinated compound, Methyl4-iodo-2-methoxybenzoate is an excellent substrate for palladium-catalyzed cross-coupling reactions including Suzuki, Heck, Negishi, Sonogashira, and Buchwald–Hartwig amination. It can also be used for Grignard reagent preparation, metal–halogen exchange with organolithium reagents, and nucleophilic substitution reactions.
Store refrigerated (2–8 °C) in a light-resistant, tightly sealed container under inert atmosphere to prevent degradation. Store at room temperature in a tightly sealed container away from heat and open flame. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.
Get competitive pricing, custom quantities, and fast USA delivery. Our chemistry team is standing by to provide specifications, CoA documentation, and a tailored quote for your project.
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