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Methyl2-bromo-3-methylbenzoate

CAS 131001-86-0 · Brominated Compound · 2 functional traits · cGMP compliant · Ships from USA in 2-3 days

Brominated Compound

Methyl2-bromo-3-methylbenzoate

Halogenated PharmaceuticalFine ChemicalAgrochemicalResearchPolymerGreen Chemistry
CAS Number 131001-86-0
Category Brominated Compound · Ester
Origin USA
Compliance cGMP

Questions? Contact our chemistry team:

chemistry@chem-contract.com | +1 (714) 732-8549
In stock — typically ships within 2-3 business days

About Methyl2-bromo-3-methylbenzoate

Methyl2-bromo-3-methylbenzoate (CAS Number: 131001-86-0) is a bromo-substituted intermediate prized for its reactivity in metal-catalyzed coupling. ChemContract Research supplies this simple-complexity compound in high purity from our Huntington Beach, California facility, ensuring consistent quality and reliable domestic delivery throughout the United States.

Aryl and alkyl bromides occupy a "Goldilocks zone" in cross-coupling — more reactive than chlorides yet more stable than iodides — making them the most commonly used coupling partners in process chemistry. Ester hydrolysis by cellular esterases is the most commonly exploited prodrug activation mechanism — enabling drugs that cannot cross biological membranes as free acids.

Primary applications include grignard reagent preparation via magnesium insertion into c–br bond and prodrug development to mask carboxylic acids and improve membrane permeability. This compound serves researchers and manufacturers across the pharmaceutical, fine chemical, agrochemical sectors. Whether you require Methyl2-bromo-3-methylbenzoate for early-stage research, process development, or commercial-scale production, ChemContract Research offers flexible ordering from milligram to multi-kilogram quantities with custom synthesis options and full batch documentation including Certificates of Analysis (CoA) and Safety Data Sheets.

Functional Groups: Ester (–COOR)Bromine (C–Br)

Brominated Compound Applications & Target Industries

How Methyl2-bromo-3-methylbenzoate is used across pharmaceutical and fine chemical sectors

01

Grignard reagent preparation via magnesium insertion into C–Br bond

02

Prodrug development to mask carboxylic acids and improve membrane permeability

03

Palladium-catalyzed Suzuki, Heck, and Negishi cross-coupling

04

Protecting group for hydroxyl functionalities (acetate, benzoate)

05

Nucleophilic substitution (SN2) for C–N, C–O, and C–S bond formation

06

Ring-opening polymerization monomer for biodegradable polymers

Target Industries: PharmaceuticalFine ChemicalAgrochemicalResearchPolymerGreen Chemistry

Methyl2-bromo-3-methylbenzoate Specifications

Detailed specifications for this brominated compound, including purity, molecular weight, and analytical data are available upon request. Every batch from ChemContract Research includes:

  • Certificate of Analysis (CoA) with purity verification
  • HPLC, NMR, and/or mass spectrometry characterization data
  • Material Safety Data Sheet (MSDS/SDS)
  • Batch-specific documentation and lot traceability
  • Custom analytical testing available on request
Request Full Specifications

Quick Reference

Compound Name Methyl2-bromo-3-methylbenzoate
Type Brominated Compound
Category Brominated Compound · Ester
Purity ≥95% (custom grades available)
Complexity Simple (2 functional groups, 0 rings)
Compliance cGMP
Packaging mg to kg scale

Storage & Handling for Brominated Compounds

Handling Guidelines

Some brominated compounds may be lachrymatory or skin irritants. Handle in a fume hood with appropriate PPE. Some esters are volatile and flammable. Handle in a well-ventilated area. Keep away from ignition sources.

Storage Conditions

Store at room temperature in a tightly sealed, light-resistant container. Some bromo compounds require refrigeration. Store at room temperature in a tightly sealed container away from heat and open flame.

Why Buy Methyl2-bromo-3-methylbenzoate From ChemContract?

Quality Assured

Every batch of Methyl2-bromo-3-methylbenzoate is produced under cGMP conditions with full CoA documentation, HPLC purity verification, and lot traceability.

Fast USA Shipping

Ship from our Huntington Beach, CA facility with 2-3 business day domestic delivery. No import delays, no customs fees, no tariff surprises.

Custom Synthesis

Need a specific grade, quantity, or derivative of Methyl2-bromo-3-methylbenzoate? Our team of PhD chemists can develop custom synthesis solutions for your exact requirements.

Frequently Asked

Common questions about Methyl2-bromo-3-methylbenzoate

What is Methyl2-bromo-3-methylbenzoate used for? +

Methyl2-bromo-3-methylbenzoate is a bromo-substituted intermediate prized for its reactivity in metal-catalyzed coupling used primarily in the pharmaceutical and fine chemical industries. Key applications include grignard reagent preparation via magnesium insertion into c–br bond and prodrug development to mask carboxylic acids and improve membrane permeability.

Where can I buy Methyl2-bromo-3-methylbenzoate in the USA? +

ChemContract Research is a trusted USA-based supplier of Methyl2-bromo-3-methylbenzoate. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.

What purity levels are available for Methyl2-bromo-3-methylbenzoate? +

ChemContract Research supplies Methyl2-bromo-3-methylbenzoate in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.

Can ChemContract synthesize Methyl2-bromo-3-methylbenzoate in custom quantities? +

Yes. ChemContract Research offers custom synthesis services for Methyl2-bromo-3-methylbenzoate from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.

What coupling reactions can I run with Methyl2-bromo-3-methylbenzoate? +

As a brominated compound, Methyl2-bromo-3-methylbenzoate is an excellent substrate for palladium-catalyzed cross-coupling reactions including Suzuki, Heck, Negishi, Sonogashira, and Buchwald–Hartwig amination. It can also be used for Grignard reagent preparation, metal–halogen exchange with organolithium reagents, and nucleophilic substitution reactions.

How should I store Methyl2-bromo-3-methylbenzoate? +

Store at room temperature in a tightly sealed, light-resistant container. Some bromo compounds require refrigeration. Store at room temperature in a tightly sealed container away from heat and open flame. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.

What is the CAS number of Methyl2-bromo-3-methylbenzoate? +

The CAS Registry Number for Methyl2-bromo-3-methylbenzoate is 131001-86-0. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.

Chemical analysis laboratory with HPLC instruments for purity and impurity testing Custom chemical synthesis reaction setup for pharmaceutical intermediate production

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