Frequently Asked
Common questions about Methyl-4-iodobenzoate
What is Methyl-4-iodobenzoate used for?
Methyl-4-iodobenzoate is an iodo-substituted compound offering high reactivity in metal-mediated transformations used primarily in the pharmaceutical and nuclear medicine industries. Key applications include sonogashira and heck coupling with the lowest activation barrier among aryl halides and prodrug development to mask carboxylic acids and improve membrane permeability.
Where can I buy Methyl-4-iodobenzoate in the USA?
ChemContract Research is a trusted USA-based supplier of Methyl-4-iodobenzoate. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.
What purity levels are available for Methyl-4-iodobenzoate?
ChemContract Research supplies Methyl-4-iodobenzoate in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.
Can ChemContract synthesize Methyl-4-iodobenzoate in custom quantities?
Yes. ChemContract Research offers custom synthesis services for Methyl-4-iodobenzoate from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.
What is the stereochemical purity of Methyl-4-iodobenzoate?
ChemContract Research supplies Methyl-4-iodobenzoate with verified enantiomeric or diastereomeric purity as documented in our Certificate of Analysis (CoA). Chiral HPLC analysis is standard for stereodefined compounds. We can provide material with ≥98% ee/de for demanding applications. Contact us for specific optical purity requirements.
What coupling reactions can I run with Methyl-4-iodobenzoate?
As a iodinated compound, Methyl-4-iodobenzoate is an excellent substrate for palladium-catalyzed cross-coupling reactions including Suzuki, Heck, Negishi, Sonogashira, and Buchwald–Hartwig amination. It can also be used for Grignard reagent preparation, metal–halogen exchange with organolithium reagents, and nucleophilic substitution reactions.
How should I store Methyl-4-iodobenzoate?
Store refrigerated (2–8 °C) in a light-resistant, tightly sealed container under inert atmosphere to prevent degradation. Store at room temperature in a tightly sealed container away from heat and open flame. Store under recommended conditions. Some chiral compounds may racemize at elevated temperatures or in the presence of base. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.
What is the CAS number of Methyl-4-iodobenzoate?
The CAS Registry Number for Methyl-4-iodobenzoate is 619-44-3. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.
