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METHYL 3-IODOBENZOATE

CAS 618-91-7 · Iodinated Compound · 2 functional traits · cGMP compliant · Ships from USA in 2-3 days

Iodinated Compound

METHYL 3-IODOBENZOATE

Halogenated PharmaceuticalNuclear MedicineFine ChemicalResearchPolymerGreen Chemistry
CAS Number 618-91-7
Category Iodinated Compound · Ester
Origin USA
Compliance cGMP

Questions? Contact our chemistry team:

chemistry@chem-contract.com | +1 (714) 732-8549
In stock — typically ships within 2-3 business days

About METHYL 3-IODOBENZOATE

METHYL 3-IODOBENZOATE (CAS Number: 618-91-7) is an iodo-substituted compound offering high reactivity in metal-mediated transformations. ChemContract Research supplies this simple-complexity compound in high purity from our Huntington Beach, California facility, ensuring consistent quality and reliable domestic delivery throughout the United States.

The C–I bond is the weakest carbon–halogen bond, which translates to the highest reactivity in oxidative addition — making aryl iodides the first-choice substrate for challenging cross-coupling reactions. Ester hydrolysis by cellular esterases is the most commonly exploited prodrug activation mechanism — enabling drugs that cannot cross biological membranes as free acids.

Primary applications include sonogashira and heck coupling with the lowest activation barrier among aryl halides and prodrug development to mask carboxylic acids and improve membrane permeability. This compound serves researchers and manufacturers across the pharmaceutical, nuclear medicine, fine chemical sectors. Whether you require METHYL 3-IODOBENZOATE for early-stage research, process development, or commercial-scale production, ChemContract Research offers flexible ordering from milligram to multi-kilogram quantities with custom synthesis options and full batch documentation including Certificates of Analysis (CoA) and Safety Data Sheets.

Functional Groups: Ester (–COOR)Iodine (C–I)

Iodinated Compound Applications & Target Industries

How METHYL 3-IODOBENZOATE is used across pharmaceutical and nuclear medicine sectors

01

Sonogashira and Heck coupling with the lowest activation barrier among aryl halides

02

Prodrug development to mask carboxylic acids and improve membrane permeability

03

Radioiodination precursor for SPECT and PET diagnostic imaging

04

Protecting group for hydroxyl functionalities (acetate, benzoate)

05

Metal–halogen exchange with n-BuLi for directed metalation strategies

06

Ring-opening polymerization monomer for biodegradable polymers

Target Industries: PharmaceuticalNuclear MedicineFine ChemicalResearchPolymerGreen Chemistry

METHYL 3-IODOBENZOATE Specifications

Detailed specifications for this iodinated compound, including purity, molecular weight, and analytical data are available upon request. Every batch from ChemContract Research includes:

  • Certificate of Analysis (CoA) with purity verification
  • HPLC, NMR, and/or mass spectrometry characterization data
  • Material Safety Data Sheet (MSDS/SDS)
  • Batch-specific documentation and lot traceability
  • Custom analytical testing available on request
Request Full Specifications

Quick Reference

Compound Name METHYL 3-IODOBENZOATE
Type Iodinated Compound
Category Iodinated Compound · Ester
Purity ≥95% (custom grades available)
Complexity Simple (2 functional groups, 0 rings)
Compliance cGMP
Packaging mg to kg scale

Storage & Handling for Iodinated Compounds

Handling Guidelines

Iodo compounds may be light-sensitive and can stain skin. Handle in a fume hood and protect from light during use. Some esters are volatile and flammable. Handle in a well-ventilated area. Keep away from ignition sources.

Storage Conditions

Store refrigerated (2–8 °C) in a light-resistant, tightly sealed container under inert atmosphere to prevent degradation. Store at room temperature in a tightly sealed container away from heat and open flame.

Why Buy METHYL 3-IODOBENZOATE From ChemContract?

Quality Assured

Every batch of METHYL 3-IODOBENZOATE is produced under cGMP conditions with full CoA documentation, HPLC purity verification, and lot traceability.

Fast USA Shipping

Ship from our Huntington Beach, CA facility with 2-3 business day domestic delivery. No import delays, no customs fees, no tariff surprises.

Custom Synthesis

Need a specific grade, quantity, or derivative of METHYL 3-IODOBENZOATE? Our team of PhD chemists can develop custom synthesis solutions for your exact requirements.

Frequently Asked

Common questions about METHYL 3-IODOBENZOATE

What is METHYL 3-IODOBENZOATE used for? +

METHYL 3-IODOBENZOATE is an iodo-substituted compound offering high reactivity in metal-mediated transformations used primarily in the pharmaceutical and nuclear medicine industries. Key applications include sonogashira and heck coupling with the lowest activation barrier among aryl halides and prodrug development to mask carboxylic acids and improve membrane permeability.

Where can I buy METHYL 3-IODOBENZOATE in the USA? +

ChemContract Research is a trusted USA-based supplier of METHYL 3-IODOBENZOATE. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.

What purity levels are available for METHYL 3-IODOBENZOATE? +

ChemContract Research supplies METHYL 3-IODOBENZOATE in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.

Can ChemContract synthesize METHYL 3-IODOBENZOATE in custom quantities? +

Yes. ChemContract Research offers custom synthesis services for METHYL 3-IODOBENZOATE from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.

What coupling reactions can I run with METHYL 3-IODOBENZOATE? +

As a iodinated compound, METHYL 3-IODOBENZOATE is an excellent substrate for palladium-catalyzed cross-coupling reactions including Suzuki, Heck, Negishi, Sonogashira, and Buchwald–Hartwig amination. It can also be used for Grignard reagent preparation, metal–halogen exchange with organolithium reagents, and nucleophilic substitution reactions.

How should I store METHYL 3-IODOBENZOATE? +

Store refrigerated (2–8 °C) in a light-resistant, tightly sealed container under inert atmosphere to prevent degradation. Store at room temperature in a tightly sealed container away from heat and open flame. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.

What is the CAS number of METHYL 3-IODOBENZOATE? +

The CAS Registry Number for METHYL 3-IODOBENZOATE is 618-91-7. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.

Chemical analysis laboratory with HPLC instruments for purity and impurity testing Custom chemical synthesis reaction setup for pharmaceutical intermediate production

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