CAS 22223-49-0 · Piperidine · 2 functional traits · cGMP compliant · Ships from USA in 2-3 days
Methyl 2-(piperidin-4-yl)acetate (CAS Number: 22223-49-0) is a piperidine-containing compound — one of the most drug-prevalent saturated N-heterocycles featuring a Piperidine ring. ChemContract Research supplies this simple-complexity compound in high purity from our Huntington Beach, California facility, ensuring consistent quality and reliable domestic delivery throughout the United States.
The piperidine ring is the most common nitrogen heterocycle in FDA-approved drugs, appearing in over 70 marketed pharmaceuticals across CNS, cardiovascular, and oncology indications. Ester hydrolysis by cellular esterases is the most commonly exploited prodrug activation mechanism — enabling drugs that cannot cross biological membranes as free acids.
Primary applications include cns drug scaffold (present in donepezil, methylphenidate, fentanyl class) and prodrug development to mask carboxylic acids and improve membrane permeability. This compound serves researchers and manufacturers across the pharmaceutical, cns therapeutics, medicinal chemistry sectors. Whether you require Methyl 2-(piperidin-4-yl)acetate for early-stage research, process development, or commercial-scale production, ChemContract Research offers flexible ordering from milligram to multi-kilogram quantities with custom synthesis options and full batch documentation including Certificates of Analysis (CoA) and Safety Data Sheets.
How Methyl 2-(piperidin-4-yl)acetate is used across pharmaceutical and cns therapeutics sectors
CNS drug scaffold (present in donepezil, methylphenidate, fentanyl class)
Prodrug development to mask carboxylic acids and improve membrane permeability
Conformationally-restricted amine for receptor binding optimization
Protecting group for hydroxyl functionalities (acetate, benzoate)
Spirocyclic and fused ring system construction for 3D drug design
Ring-opening polymerization monomer for biodegradable polymers
Detailed specifications for this piperidine, including purity, molecular weight, and analytical data are available upon request. Every batch from ChemContract Research includes:
Handle with standard precautions. Piperidine and some derivatives have strong amine odors. Use a fume hood. Some esters are volatile and flammable. Handle in a well-ventilated area. Keep away from ignition sources.
Store at room temperature in a well-sealed container. Some N-unsubstituted piperidines are volatile. Store at room temperature in a tightly sealed container away from heat and open flame.
Piperidine scaffolds like Methyl 2-(piperidin-4-yl)acetate are found in 70+ marketed drugs. We stock common analogs for rapid medicinal chemistry screening.
Every batch of Methyl 2-(piperidin-4-yl)acetate is produced under cGMP conditions with full CoA documentation, HPLC purity verification, and lot traceability.
Ship from our Huntington Beach, CA facility with 2-3 business day domestic delivery. No import delays, no customs fees, no tariff surprises.
Need a specific grade, quantity, or derivative of Methyl 2-(piperidin-4-yl)acetate? Our team of PhD chemists can develop custom synthesis solutions for your exact requirements.
Common questions about Methyl 2-(piperidin-4-yl)acetate
Methyl 2-(piperidin-4-yl)acetate is a piperidine-containing compound — one of the most drug-prevalent saturated N-heterocycles used primarily in the pharmaceutical and cns therapeutics industries. Key applications include cns drug scaffold (present in donepezil, methylphenidate, fentanyl class) and prodrug development to mask carboxylic acids and improve membrane permeability.
ChemContract Research is a trusted USA-based supplier of Methyl 2-(piperidin-4-yl)acetate. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.
ChemContract Research supplies Methyl 2-(piperidin-4-yl)acetate in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.
Yes. ChemContract Research offers custom synthesis services for Methyl 2-(piperidin-4-yl)acetate from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.
The Piperidine ring system(s) in Methyl 2-(piperidin-4-yl)acetate is a privileged structure in medicinal chemistry, appearing in numerous FDA-approved drugs. This scaffold is commonly used in kinase inhibitor design, GPCR modulator development, and lead optimization programs. ChemContract supplies this building block for early-stage discovery through process-scale manufacturing.
Store at room temperature in a well-sealed container. Some N-unsubstituted piperidines are volatile. Store at room temperature in a tightly sealed container away from heat and open flame. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.
The CAS Registry Number for Methyl 2-(piperidin-4-yl)acetate is 22223-49-0. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.
Get competitive pricing, custom quantities, and fast USA delivery. Our chemistry team is standing by to provide specifications, CoA documentation, and a tailored quote for your project.
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