Search 7,000+ Chemicals

Start typing to search our catalog

Ethyl 4-amino-3-methoxypiperidine-1-carboxylate hydrochloride

CAS 83863-71-2 · Amine · 3 functional traits · cGMP compliant · Ships from USA in 2-3 days

Amine

Ethyl 4-amino-3-methoxypiperidine-1-carboxylate hydrochloride

Piperidines PharmaceuticalPolymerAgrochemicalCatalysisCNS TherapeuticsMedicinal Chemistry
CAS Number 83863-71-2
Category Amine · Piperidine
Origin USA
Compliance cGMP

Questions? Contact our chemistry team:

chemistry@chem-contract.com | +1 (714) 732-8549
In stock — typically ships within 2-3 business days

About Ethyl 4-amino-3-methoxypiperidine-1-carboxylate hydrochloride

Ethyl 4-amino-3-methoxypiperidine-1-carboxylate hydrochloride (CAS Number: 83863-71-2) is an amine-functionalized compound with nucleophilic nitrogen reactivity featuring a Piperidine ring. ChemContract Research supplies this moderate-complexity compound in high purity from our Huntington Beach, California facility, ensuring consistent quality and reliable domestic delivery throughout the United States. Supplied as the hydrochloride salt form for enhanced stability and handling.

Amines are among the most prevalent functional groups in drug molecules — over 80% of small-molecule pharmaceuticals contain at least one amine moiety. The piperidine ring is the most common nitrogen heterocycle in FDA-approved drugs, appearing in over 70 marketed pharmaceuticals across CNS, cardiovascular, and oncology indications. Hydrochloride is the most common salt form for basic drug substances — approximately half of all salt-form drugs on the market are HCl salts, valued for their crystallinity and aqueous solubility.

Primary applications include buchwald–hartwig amination for aryl c–n bond construction and cns drug scaffold (present in donepezil, methylphenidate, fentanyl class). This compound serves researchers and manufacturers across the pharmaceutical, polymer, agrochemical sectors. Whether you require Ethyl 4-amino-3-methoxypiperidine-1-carboxylate hydrochloride for early-stage research, process development, or commercial-scale production, ChemContract Research offers flexible ordering from milligram to multi-kilogram quantities with custom synthesis options and full batch documentation including Certificates of Analysis (CoA) and Safety Data Sheets.

Ring Systems: Piperidine
Functional Groups: Amine (–NH₂/–NHR)Chlorine (C–Cl)Alkoxy (–OR)
Salt Form: Hydrochloride

Amine Applications & Target Industries

How Ethyl 4-amino-3-methoxypiperidine-1-carboxylate hydrochloride is used across pharmaceutical and polymer sectors

01

Buchwald–Hartwig amination for aryl C–N bond construction

02

CNS drug scaffold (present in donepezil, methylphenidate, fentanyl class)

03

Improved handling characteristics versus the free base form

04

Reductive amination with aldehydes and ketones for secondary amine synthesis

05

Conformationally-restricted amine for receptor binding optimization

06

Direct formulation excipient in oral solid dosage forms

Target Industries: PharmaceuticalPolymerAgrochemicalCatalysisCNS TherapeuticsMedicinal Chemistry

Ethyl 4-amino-3-methoxypiperidine-1-carboxylate hydrochloride Specifications

Detailed specifications for this amine, including purity, molecular weight, and analytical data are available upon request. Every batch from ChemContract Research includes:

  • Certificate of Analysis (CoA) with purity verification
  • HPLC, NMR, and/or mass spectrometry characterization data
  • Material Safety Data Sheet (MSDS/SDS)
  • Batch-specific documentation and lot traceability
  • Custom analytical testing available on request
Request Full Specifications

Quick Reference

Compound Name Ethyl 4-amino-3-methoxypiperidine-1-carboxylate hydrochloride
Type Amine
Category Amine · Piperidine
Purity ≥95% (custom grades available)
Salt Form Hydrochloride
Complexity Moderate (3 functional groups, 1 ring)
Compliance cGMP
Packaging mg to kg scale

Storage & Handling for Amines

Handling Guidelines

Amines may have strong odors and can be corrosive to skin. Handle under adequate ventilation with chemical-resistant gloves and eye protection. Handle with standard precautions. Piperidine and some derivatives have strong amine odors. Use a fume hood. Handle with standard precautions. Hydrochloride salts are generally more stable than free bases.

Storage Conditions

Store in a cool, well-ventilated area away from acids and oxidizing agents. Keep containers tightly sealed as many amines are hygroscopic. Store at room temperature in a well-sealed container. Some N-unsubstituted piperidines are volatile. Store at room temperature in a tightly sealed container. Protect from humidity.

Why Buy Ethyl 4-amino-3-methoxypiperidine-1-carboxylate hydrochloride From ChemContract?

Quality Assured

Every batch of Ethyl 4-amino-3-methoxypiperidine-1-carboxylate hydrochloride is produced under cGMP conditions with full CoA documentation, HPLC purity verification, and lot traceability.

Fast USA Shipping

Ship from our Huntington Beach, CA facility with 2-3 business day domestic delivery. No import delays, no customs fees, no tariff surprises.

Custom Synthesis

Need a specific grade, quantity, or derivative of Ethyl 4-amino-3-methoxypiperidine-1-carboxylate hydrochloride? Our team of PhD chemists can develop custom synthesis solutions for your exact requirements.

Frequently Asked

Common questions about Ethyl 4-amino-3-methoxypiperidine-1-carboxylate hydrochloride

What is Ethyl 4-amino-3-methoxypiperidine-1-carboxylate hydrochloride used for? +

Ethyl 4-amino-3-methoxypiperidine-1-carboxylate hydrochloride is an amine-functionalized compound with nucleophilic nitrogen reactivity used primarily in the pharmaceutical and polymer industries. Key applications include buchwald–hartwig amination for aryl c–n bond construction and cns drug scaffold (present in donepezil, methylphenidate, fentanyl class).

Where can I buy Ethyl 4-amino-3-methoxypiperidine-1-carboxylate hydrochloride in the USA? +

ChemContract Research is a trusted USA-based supplier of Ethyl 4-amino-3-methoxypiperidine-1-carboxylate hydrochloride. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.

What purity levels are available for Ethyl 4-amino-3-methoxypiperidine-1-carboxylate hydrochloride? +

ChemContract Research supplies Ethyl 4-amino-3-methoxypiperidine-1-carboxylate hydrochloride in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.

Can ChemContract synthesize Ethyl 4-amino-3-methoxypiperidine-1-carboxylate hydrochloride in custom quantities? +

Yes. ChemContract Research offers custom synthesis services for Ethyl 4-amino-3-methoxypiperidine-1-carboxylate hydrochloride from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.

Can I get Ethyl 4-amino-3-methoxypiperidine-1-carboxylate hydrochloride in a different salt form or as the free base? +

Yes. ChemContract Research can supply Ethyl 4-amino-3-methoxypiperidine-1-carboxylate hydrochloride as the free base or convert it to alternative salt forms including hydrochloride, mesylate, tosylate, fumarate, or other pharmaceutically acceptable counter-ions. Salt form selection impacts crystallinity, stability, and solubility — our chemistry team can advise on optimal salt selection for your application. Currently supplied as the Hydrochloride form.

What reactions can I perform with the amine group in Ethyl 4-amino-3-methoxypiperidine-1-carboxylate hydrochloride? +

The amine functionality in Ethyl 4-amino-3-methoxypiperidine-1-carboxylate hydrochloride enables diverse transformations: reductive amination with aldehydes/ketones, acylation to form amides, sulfonylation to form sulfonamides, Buchwald–Hartwig coupling with aryl halides, urea and carbamate formation, and salt generation for improved drug properties. The nucleophilicity of the nitrogen makes it one of the most versatile handles in synthetic chemistry.

How should I store Ethyl 4-amino-3-methoxypiperidine-1-carboxylate hydrochloride? +

Store in a cool, well-ventilated area away from acids and oxidizing agents. Keep containers tightly sealed as many amines are hygroscopic. Store at room temperature in a well-sealed container. Some N-unsubstituted piperidines are volatile. Store at room temperature in a tightly sealed container. Protect from humidity. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.

What is the CAS number of Ethyl 4-amino-3-methoxypiperidine-1-carboxylate hydrochloride? +

The CAS Registry Number for Ethyl 4-amino-3-methoxypiperidine-1-carboxylate hydrochloride is 83863-71-2. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.

Chemical analysis laboratory with HPLC instruments for purity and impurity testing Custom chemical synthesis reaction setup for pharmaceutical intermediate production

Get Ethyl 4-amino-3-methoxypiperidine-1-carboxylate hydrochloride Delivered This Week

Get competitive pricing, custom quantities, and fast USA delivery. Our chemistry team is standing by to provide specifications, CoA documentation, and a tailored quote for your project.

Or call us directly: +1 (714) 732-8549

ChemContract

Let's Build
Your Molecule

From discovery to commercial scale — our 500+ scientists are ready to accelerate your project.

24-Hour ResponseFast turnaround guaranteed
60+ FacilitiesGlobal R&D network
cGMP CompliantFDA-ready manufacturing

Request a Quote

Tell us about your compound and we'll send a detailed quote within 24 hours.

Contact Information
Chemical Specifications
ChemContract
Mon-Fri 8AM-5PM PT

Hi there! How can we help you today?