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Ethyl (2-amino-4-hydroxy-6-methyl-5-pyrimidinyl)acetate >95%

CAS 499209-19-7 · Amine · 4 functional traits · cGMP compliant · Ships from USA in 2-3 days

Amine

Ethyl (2-amino-4-hydroxy-6-methyl-5-pyrimidinyl)acetate >95%

Esters PharmaceuticalPolymerAgrochemicalCatalysisFine ChemicalGreen Chemistry
CAS Number 499209-19-7
Category Amine · Ester
Origin USA
Compliance cGMP

Questions? Contact our chemistry team:

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About Ethyl (2-amino-4-hydroxy-6-methyl-5-pyrimidinyl)acetate >95%

Ethyl (2-amino-4-hydroxy-6-methyl-5-pyrimidinyl)acetate >95% (CAS Number: 499209-19-7) is an amine-functionalized compound with nucleophilic nitrogen reactivity featuring a Pyrimidine ring with defined stereochemistry. ChemContract Research supplies this moderate-complexity compound in high purity from our Huntington Beach, California facility, ensuring consistent quality and reliable domestic delivery throughout the United States.

Amines are among the most prevalent functional groups in drug molecules — over 80% of small-molecule pharmaceuticals contain at least one amine moiety. Ester hydrolysis by cellular esterases is the most commonly exploited prodrug activation mechanism — enabling drugs that cannot cross biological membranes as free acids. Hydroxyl groups are critical pharmacophores — they serve as hydrogen-bond donors and acceptors, influencing drug–target binding, aqueous solubility, and metabolic susceptibility.

Primary applications include buchwald–hartwig amination for aryl c–n bond construction and prodrug development to mask carboxylic acids and improve membrane permeability. This compound serves researchers and manufacturers across the pharmaceutical, polymer, agrochemical sectors. Whether you require Ethyl (2-amino-4-hydroxy-6-methyl-5-pyrimidinyl)acetate >95% for early-stage research, process development, or commercial-scale production, ChemContract Research offers flexible ordering from milligram to multi-kilogram quantities with custom synthesis options and full batch documentation including Certificates of Analysis (CoA) and Safety Data Sheets.

Ring Systems: Pyrimidine
Functional Groups: Amine (–NH₂/–NHR)Ester (–COOR)Hydroxyl (–OH)
Stereochemistry: Defined Configuration

Amine Applications & Target Industries

How Ethyl (2-amino-4-hydroxy-6-methyl-5-pyrimidinyl)acetate >95% is used across pharmaceutical and polymer sectors

01

Buchwald–Hartwig amination for aryl C–N bond construction

02

Prodrug development to mask carboxylic acids and improve membrane permeability

03

Mitsunobu reaction substrate for stereospecific inversion at chiral centers

04

Enantiopure building block for single-enantiomer drug development

05

Reductive amination with aldehydes and ketones for secondary amine synthesis

06

Protecting group for hydroxyl functionalities (acetate, benzoate)

Target Industries: PharmaceuticalPolymerAgrochemicalCatalysisFine ChemicalGreen Chemistry

Ethyl (2-amino-4-hydroxy-6-methyl-5-pyrimidinyl)acetate >95% Specifications

Detailed specifications for this amine, including purity, molecular weight, and analytical data are available upon request. Every batch from ChemContract Research includes:

  • Certificate of Analysis (CoA) with purity verification
  • HPLC, NMR, and/or mass spectrometry characterization data
  • Material Safety Data Sheet (MSDS/SDS)
  • Batch-specific documentation and lot traceability
  • Custom analytical testing available on request
Request Full Specifications

Quick Reference

Compound Name Ethyl (2-amino-4-hydroxy-6-methyl-5-pyrimidinyl)acetate >95%
Type Amine
Category Amine · Ester
Purity ≥95% (custom grades available)
Stereochemistry Defined configuration (chiral HPLC verified)
Complexity Moderate (3 functional groups, 1 ring)
Compliance cGMP
Packaging mg to kg scale

Storage & Handling for Amines

Handling Guidelines

Amines may have strong odors and can be corrosive to skin. Handle under adequate ventilation with chemical-resistant gloves and eye protection. Some esters are volatile and flammable. Handle in a well-ventilated area. Keep away from ignition sources. Handle with standard precautions. Some alcohols are flammable. Use adequate ventilation and appropriate PPE. Handle with standard precautions. Ensure proper labeling of stereochemical identity to prevent mix-ups.

Storage Conditions

Store in a cool, well-ventilated area away from acids and oxidizing agents. Keep containers tightly sealed as many amines are hygroscopic. Store at room temperature in a tightly sealed container away from heat and open flame. Store at room temperature in a tightly sealed container away from heat sources and oxidizers. Store under recommended conditions. Some chiral compounds may racemize at elevated temperatures or in the presence of base.

Why Buy Ethyl (2-amino-4-hydroxy-6-methyl-5-pyrimidinyl)acetate >95% From ChemContract?

Quality Assured

Every batch of Ethyl (2-amino-4-hydroxy-6-methyl-5-pyrimidinyl)acetate >95% is produced under cGMP conditions with full CoA documentation, HPLC purity verification, and lot traceability.

Fast USA Shipping

Ship from our Huntington Beach, CA facility with 2-3 business day domestic delivery. No import delays, no customs fees, no tariff surprises.

Custom Synthesis

Need a specific grade, quantity, or derivative of Ethyl (2-amino-4-hydroxy-6-methyl-5-pyrimidinyl)acetate >95%? Our team of PhD chemists can develop custom synthesis solutions for your exact requirements.

Frequently Asked

Common questions about Ethyl (2-amino-4-hydroxy-6-methyl-5-pyrimidinyl)acetate >95%

What is Ethyl (2-amino-4-hydroxy-6-methyl-5-pyrimidinyl)acetate >95% used for? +

Ethyl (2-amino-4-hydroxy-6-methyl-5-pyrimidinyl)acetate >95% is an amine-functionalized compound with nucleophilic nitrogen reactivity used primarily in the pharmaceutical and polymer industries. Key applications include buchwald–hartwig amination for aryl c–n bond construction and prodrug development to mask carboxylic acids and improve membrane permeability.

Where can I buy Ethyl (2-amino-4-hydroxy-6-methyl-5-pyrimidinyl)acetate >95% in the USA? +

ChemContract Research is a trusted USA-based supplier of Ethyl (2-amino-4-hydroxy-6-methyl-5-pyrimidinyl)acetate >95%. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.

What purity levels are available for Ethyl (2-amino-4-hydroxy-6-methyl-5-pyrimidinyl)acetate >95%? +

ChemContract Research supplies Ethyl (2-amino-4-hydroxy-6-methyl-5-pyrimidinyl)acetate >95% in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.

Can ChemContract synthesize Ethyl (2-amino-4-hydroxy-6-methyl-5-pyrimidinyl)acetate >95% in custom quantities? +

Yes. ChemContract Research offers custom synthesis services for Ethyl (2-amino-4-hydroxy-6-methyl-5-pyrimidinyl)acetate >95% from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.

What is the stereochemical purity of Ethyl (2-amino-4-hydroxy-6-methyl-5-pyrimidinyl)acetate >95%? +

ChemContract Research supplies Ethyl (2-amino-4-hydroxy-6-methyl-5-pyrimidinyl)acetate >95% with verified enantiomeric or diastereomeric purity as documented in our Certificate of Analysis (CoA). Chiral HPLC analysis is standard for stereodefined compounds. We can provide material with ≥98% ee/de for demanding applications. Contact us for specific optical purity requirements.

What reactions can I perform with the amine group in Ethyl (2-amino-4-hydroxy-6-methyl-5-pyrimidinyl)acetate >95%? +

The amine functionality in Ethyl (2-amino-4-hydroxy-6-methyl-5-pyrimidinyl)acetate >95% enables diverse transformations: reductive amination with aldehydes/ketones, acylation to form amides, sulfonylation to form sulfonamides, Buchwald–Hartwig coupling with aryl halides, urea and carbamate formation, and salt generation for improved drug properties. The nucleophilicity of the nitrogen makes it one of the most versatile handles in synthetic chemistry.

How should I store Ethyl (2-amino-4-hydroxy-6-methyl-5-pyrimidinyl)acetate >95%? +

Store in a cool, well-ventilated area away from acids and oxidizing agents. Keep containers tightly sealed as many amines are hygroscopic. Store at room temperature in a tightly sealed container away from heat and open flame. Store at room temperature in a tightly sealed container away from heat sources and oxidizers. Store under recommended conditions. Some chiral compounds may racemize at elevated temperatures or in the presence of base. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.

What is the CAS number of Ethyl (2-amino-4-hydroxy-6-methyl-5-pyrimidinyl)acetate >95%? +

The CAS Registry Number for Ethyl (2-amino-4-hydroxy-6-methyl-5-pyrimidinyl)acetate >95% is 499209-19-7. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.

Chemical analysis laboratory with HPLC instruments for purity and impurity testing Custom chemical synthesis reaction setup for pharmaceutical intermediate production

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