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Ethyl 1-Boc-5-oxo-hexahydro-1H-azepine-4-carboxylate

CAS 141642-82-2 · Ketone · 2 functional traits · cGMP compliant · Ships from USA in 2-3 days

Ketone

Ethyl 1-Boc-5-oxo-hexahydro-1H-azepine-4-carboxylate

Boc-Protected PharmaceuticalFine ChemicalAgrochemicalResearchPeptide SynthesisBiotech
CAS Number 141642-82-2
Category Ketone · Boc-Protected
Origin USA
Compliance cGMP

Questions? Contact our chemistry team:

chemistry@chem-contract.com | +1 (714) 732-8549
In stock — typically ships within 2-3 business days

About Ethyl 1-Boc-5-oxo-hexahydro-1H-azepine-4-carboxylate

Ethyl 1-Boc-5-oxo-hexahydro-1H-azepine-4-carboxylate (CAS Number: 141642-82-2) is a ketone-containing compound with a carbonyl center flanked by carbon substituents. ChemContract Research supplies this simple-complexity compound in high purity from our Huntington Beach, California facility, ensuring consistent quality and reliable domestic delivery throughout the United States.

Ketones serve as strategic intermediates in retrosynthetic planning — their carbonyl can be disconnected in multiple directions, providing flexible synthetic access to complex targets. The Boc group is removed cleanly with TFA or HCl in dioxane, making it orthogonal to Fmoc, Cbz, and Alloc protecting groups — essential for synthesizing complex peptide therapeutics.

Primary applications include asymmetric reduction to chiral alcohols using cbs or noyori catalysts and solid-phase peptide synthesis (spps) with orthogonal boc/fmoc strategies. This compound serves researchers and manufacturers across the pharmaceutical, fine chemical, agrochemical sectors. Whether you require Ethyl 1-Boc-5-oxo-hexahydro-1H-azepine-4-carboxylate for early-stage research, process development, or commercial-scale production, ChemContract Research offers flexible ordering from milligram to multi-kilogram quantities with custom synthesis options and full batch documentation including Certificates of Analysis (CoA) and Safety Data Sheets.

Functional Groups: Boc protecting group

Ketone Applications & Target Industries

How Ethyl 1-Boc-5-oxo-hexahydro-1H-azepine-4-carboxylate is used across pharmaceutical and fine chemical sectors

01

Asymmetric reduction to chiral alcohols using CBS or Noyori catalysts

02

Solid-phase peptide synthesis (SPPS) with orthogonal Boc/Fmoc strategies

03

Grignard and organolithium additions for tertiary alcohol synthesis

04

Multi-step pharmaceutical synthesis requiring selective amine deprotection

05

Baeyer–Villiger oxidation to lactones and esters

06

Amino acid and peptide intermediate production under cGMP

Target Industries: PharmaceuticalFine ChemicalAgrochemicalResearchPeptide SynthesisBiotech

Ethyl 1-Boc-5-oxo-hexahydro-1H-azepine-4-carboxylate Specifications

Detailed specifications for this ketone, including purity, molecular weight, and analytical data are available upon request. Every batch from ChemContract Research includes:

  • Certificate of Analysis (CoA) with purity verification
  • HPLC, NMR, and/or mass spectrometry characterization data
  • Material Safety Data Sheet (MSDS/SDS)
  • Batch-specific documentation and lot traceability
  • Custom analytical testing available on request
Request Full Specifications

Quick Reference

Compound Name Ethyl 1-Boc-5-oxo-hexahydro-1H-azepine-4-carboxylate
Type Ketone
Category Ketone · Boc-Protected
Purity ≥95% (custom grades available)
Complexity Simple (1 functional groups, 0 rings)
Compliance cGMP
Packaging mg to kg scale

Storage & Handling for Ketones

Handling Guidelines

Handle with standard laboratory precautions. Some ketones are flammable. Use adequate ventilation and wear safety glasses and gloves. Boc-protected compounds are generally stable. TFA deprotection generates isobutylene gas — perform in a fume hood.

Storage Conditions

Store at room temperature in a tightly sealed container. Protect from direct sunlight and heat sources. Store at room temperature in a sealed container. Stable under neutral and basic conditions; avoid strong acids during storage.

Why Buy Ethyl 1-Boc-5-oxo-hexahydro-1H-azepine-4-carboxylate From ChemContract?

Quality Assured

Every batch of Ethyl 1-Boc-5-oxo-hexahydro-1H-azepine-4-carboxylate is produced under cGMP conditions with full CoA documentation, HPLC purity verification, and lot traceability.

Fast USA Shipping

Ship from our Huntington Beach, CA facility with 2-3 business day domestic delivery. No import delays, no customs fees, no tariff surprises.

Custom Synthesis

Need a specific grade, quantity, or derivative of Ethyl 1-Boc-5-oxo-hexahydro-1H-azepine-4-carboxylate? Our team of PhD chemists can develop custom synthesis solutions for your exact requirements.

Frequently Asked

Common questions about Ethyl 1-Boc-5-oxo-hexahydro-1H-azepine-4-carboxylate

What is Ethyl 1-Boc-5-oxo-hexahydro-1H-azepine-4-carboxylate used for? +

Ethyl 1-Boc-5-oxo-hexahydro-1H-azepine-4-carboxylate is a ketone-containing compound with a carbonyl center flanked by carbon substituents used primarily in the pharmaceutical and fine chemical industries. Key applications include asymmetric reduction to chiral alcohols using cbs or noyori catalysts and solid-phase peptide synthesis (spps) with orthogonal boc/fmoc strategies.

Where can I buy Ethyl 1-Boc-5-oxo-hexahydro-1H-azepine-4-carboxylate in the USA? +

ChemContract Research is a trusted USA-based supplier of Ethyl 1-Boc-5-oxo-hexahydro-1H-azepine-4-carboxylate. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.

What purity levels are available for Ethyl 1-Boc-5-oxo-hexahydro-1H-azepine-4-carboxylate? +

ChemContract Research supplies Ethyl 1-Boc-5-oxo-hexahydro-1H-azepine-4-carboxylate in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.

Can ChemContract synthesize Ethyl 1-Boc-5-oxo-hexahydro-1H-azepine-4-carboxylate in custom quantities? +

Yes. ChemContract Research offers custom synthesis services for Ethyl 1-Boc-5-oxo-hexahydro-1H-azepine-4-carboxylate from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.

How do I remove the Boc group from Ethyl 1-Boc-5-oxo-hexahydro-1H-azepine-4-carboxylate? +

The Boc protecting group in Ethyl 1-Boc-5-oxo-hexahydro-1H-azepine-4-carboxylate is cleanly removed by treatment with trifluoroacetic acid (TFA, 20–50% in DCM) at room temperature, typically within 30–60 minutes. Alternative conditions include HCl in dioxane (4M) or trimethylsilyl triflate with 2,6-lutidine. The Boc group is stable to base, hydrogenation, and many nucleophilic conditions, making it orthogonal to Fmoc and Cbz groups.

How should I store Ethyl 1-Boc-5-oxo-hexahydro-1H-azepine-4-carboxylate? +

Store at room temperature in a tightly sealed container. Protect from direct sunlight and heat sources. Store at room temperature in a sealed container. Stable under neutral and basic conditions; avoid strong acids during storage. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.

What is the CAS number of Ethyl 1-Boc-5-oxo-hexahydro-1H-azepine-4-carboxylate? +

The CAS Registry Number for Ethyl 1-Boc-5-oxo-hexahydro-1H-azepine-4-carboxylate is 141642-82-2. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.

Chemical analysis laboratory with HPLC instruments for purity and impurity testing Custom chemical synthesis reaction setup for pharmaceutical intermediate production

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