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Coumarin 343 X NHS ester

CAS 946123-12-2 · Amine-Reactive NHS Ester · cGMP compliant · Ships from our U.S. location

Amine-Reactive NHS Ester

Coumarin 343 X NHS ester

Esters BiotechnologyDiagnosticsLife Science ResearchPharmaceutical
CAS Number 946123-12-2
FormulaC26H29N3O7
Mol. Weight495.52
Purity95%

Questions? Contact our chemistry team:

chemistry@chem-contract.com | +1 (714) 732-8549
In stock — typically ships within 2-3 business days

About Coumarin 343 X NHS ester

Coumarin 343 X NHS ester (CAS Number: 946123-12-2) is an amine-reactive fluorescent labeling reagent with an activated NHS ester group featuring a Coumarin ring. ChemContract Research supplies this moderate-complexity compound in high purity from our U.S. location, ensuring consistent quality and reliable domestic delivery throughout the United States.

The activated NHS ester reacts selectively with primary amino groups to form stable amide bonds, while the aminohexanoyl spacer improves solubility and separation between the fluorophore and labeled target.

Primary applications include covalent labeling of proteins and peptides through primary amines. This compound serves researchers and manufacturers across the biotechnology, diagnostics, life science research sectors. Whether you require Coumarin 343 X NHS ester for early-stage research, process development, or commercial-scale production, ChemContract Research offers flexible ordering from milligram to multi-kilogram quantities with custom synthesis options and full batch documentation including Certificates of Analysis (CoA) and Safety Data Sheets.

Ring Systems: Coumarin
Functional Groups: Activated NHS esterEster (–COOR)

Amine-Reactive NHS Ester Applications & Target Industries

How Coumarin 343 X NHS ester is used across biotechnology and diagnostics sectors

01

Covalent labeling of proteins and peptides through primary amines

02

Construction of FRET-based assays and fluorescent bioconjugates

03

Fluorescence microscopy and blue-light detection workflows

04

Preparation of dye-labeled antibodies and other biomolecules

Target Industries: BiotechnologyDiagnosticsLife Science ResearchPharmaceutical

Coumarin 343 X NHS ester Specifications

Detailed specifications for this amine-reactive nhs ester, including purity, molecular weight, and analytical data are available upon request. Every batch from ChemContract Research includes:

  • Certificate of Analysis (CoA) with purity verification
  • HPLC, NMR, and/or mass spectrometry characterization data
  • Material Safety Data Sheet (MSDS/SDS)
  • Batch-specific documentation and lot traceability
  • Custom analytical testing available on request
Request Full Specifications

Quick Reference

Compound Name Coumarin 343 X NHS ester
Type Amine-Reactive NHS Ester
Category Amine-Reactive NHS Ester
Purity ≥95% (custom grades available)
Complexity Moderate (2 functional groups, 1 ring)
Compliance cGMP
Packaging mg to kg scale

Storage & Handling for Amine-Reactive NHS Esters

Handling Guidelines

NHS esters are moisture-sensitive and react with primary amines. Handle under dry conditions with appropriate laboratory PPE and consult the product SDS before use.

Storage Conditions

Store desiccated at –20 °C in the dark. Avoid prolonged exposure to light and moisture.

Why Buy Coumarin 343 X NHS ester From ChemContract?

Quality Assured

Every batch of Coumarin 343 X NHS ester is produced under cGMP conditions with full CoA documentation, HPLC purity verification, and lot traceability.

Shipped from Our U.S. Location

Products ship from our U.S. location with reliable domestic delivery and straightforward order coordination.

Custom Synthesis

Need a specific grade, quantity, or derivative of Coumarin 343 X NHS ester? Our team of PhD chemists can develop custom synthesis solutions for your exact requirements.

Frequently Asked

Common questions about Coumarin 343 X NHS ester

What is Coumarin 343 X NHS ester used for? +

Coumarin 343 X NHS ester is an amine-reactive fluorescent labeling reagent with an activated NHS ester group used primarily in the biotechnology and diagnostics industries. Key applications include covalent labeling of proteins and peptides through primary amines and construction of fret-based assays and fluorescent bioconjugates.

Where can I buy Coumarin 343 X NHS ester in the USA? +

ChemContract Research is a trusted USA-based supplier of Coumarin 343 X NHS ester. We offer competitive pricing, fast shipping from our U.S. location, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.

What purity levels are available for Coumarin 343 X NHS ester? +

ChemContract Research supplies Coumarin 343 X NHS ester in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.

Can ChemContract synthesize Coumarin 343 X NHS ester in custom quantities? +

Yes. ChemContract Research offers custom synthesis services for Coumarin 343 X NHS ester from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.

How should I store Coumarin 343 X NHS ester? +

Store desiccated at –20 °C in the dark. Avoid prolonged exposure to light and moisture. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.

What is the CAS number of Coumarin 343 X NHS ester? +

The CAS Registry Number for Coumarin 343 X NHS ester is 946123-12-2. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.

Chemical analysis laboratory with HPLC instruments for purity and impurity testing Custom chemical synthesis reaction setup for pharmaceutical intermediate production

Get Coumarin 343 X NHS ester Delivered This Week

Get competitive pricing, custom quantities, and fast USA delivery. Our chemistry team is standing by to provide specifications, CoA documentation, and a tailored quote for your project.

Or call us directly: +1 (714) 732-8549

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