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cis-3-fluorocyclobutanamine hydrochloride

CAS 1408075-13-7 · Fluorinated Compound · 3 functional traits · cGMP compliant · Ships from USA in 2-3 days

Fluorinated Compound

cis-3-fluorocyclobutanamine hydrochloride

Fluorinated PharmaceuticalDiagnostic ImagingAgrochemicalMaterials ScienceFormulationAnalytical Chemistry
CAS Number 1408075-13-7
Category Fluorinated Compound · Hydrochloride Salt
Origin USA
Compliance cGMP

Questions? Contact our chemistry team:

chemistry@chem-contract.com | +1 (714) 732-8549
In stock — typically ships within 2-3 business days

About cis-3-fluorocyclobutanamine hydrochloride

cis-3-fluorocyclobutanamine hydrochloride (CAS Number: 1408075-13-7) is a fluorine-containing building block with enhanced metabolic stability with defined stereochemistry. ChemContract Research supplies this moderate-complexity compound in high purity from our Huntington Beach, California facility, ensuring consistent quality and reliable domestic delivery throughout the United States. Supplied as the hydrochloride salt form for enhanced stability and handling.

The carbon–fluorine bond is the strongest single bond to carbon (485 kJ/mol). This exceptional stability underpins the "fluorine scan" strategy used in medicinal chemistry to optimize drug candidates. Hydrochloride is the most common salt form for basic drug substances — approximately half of all salt-form drugs on the market are HCl salts, valued for their crystallinity and aqueous solubility. Chirality matters profoundly in drug action — enantiomers can differ by orders of magnitude in potency, and FDA guidelines increasingly require single-enantiomer development.

Primary applications include metabolic blocking strategy — fluorine substitution to improve drug half-life and improved handling characteristics versus the free base form. This compound serves researchers and manufacturers across the pharmaceutical, diagnostic imaging, agrochemical sectors. Whether you require cis-3-fluorocyclobutanamine hydrochloride for early-stage research, process development, or commercial-scale production, ChemContract Research offers flexible ordering from milligram to multi-kilogram quantities with custom synthesis options and full batch documentation including Certificates of Analysis (CoA) and Safety Data Sheets.

Functional Groups: Fluorine (C–F)Chlorine (C–Cl)
Stereochemistry: Defined Configuration
Salt Form: Hydrochloride

Fluorinated Compound Applications & Target Industries

How cis-3-fluorocyclobutanamine hydrochloride is used across pharmaceutical and diagnostic imaging sectors

01

Metabolic blocking strategy — fluorine substitution to improve drug half-life

02

Improved handling characteristics versus the free base form

03

Enantiopure building block for single-enantiomer drug development

04

PET radiotracer precursor ([¹⁸F]-labeling) for diagnostic imaging

05

Direct formulation excipient in oral solid dosage forms

06

Chiral resolution standard or chiral HPLC reference compound

Target Industries: PharmaceuticalDiagnostic ImagingAgrochemicalMaterials ScienceFormulationAnalytical Chemistry

cis-3-fluorocyclobutanamine hydrochloride Specifications

Detailed specifications for this fluorinated compound, including purity, molecular weight, and analytical data are available upon request. Every batch from ChemContract Research includes:

  • Certificate of Analysis (CoA) with purity verification
  • HPLC, NMR, and/or mass spectrometry characterization data
  • Material Safety Data Sheet (MSDS/SDS)
  • Batch-specific documentation and lot traceability
  • Custom analytical testing available on request
Request Full Specifications

Quick Reference

Compound Name cis-3-fluorocyclobutanamine hydrochloride
Type Fluorinated Compound
Category Fluorinated Compound · Hydrochloride Salt
Purity ≥95% (custom grades available)
Stereochemistry Defined configuration (chiral HPLC verified)
Salt Form Hydrochloride
Complexity Moderate (2 functional groups, 0 rings)
Compliance cGMP
Packaging mg to kg scale

Storage & Handling for Fluorinated Compounds

Handling Guidelines

Handle with care in a well-ventilated fume hood. Some fluorinated compounds may release HF upon decomposition. Use chemical-resistant gloves. Handle with standard precautions. Hydrochloride salts are generally more stable than free bases. Handle with standard precautions. Ensure proper labeling of stereochemical identity to prevent mix-ups.

Storage Conditions

Store at recommended temperature in a tightly sealed container. Protect from moisture, heat, and incompatible materials. Store at room temperature in a tightly sealed container. Protect from humidity. Store under recommended conditions. Some chiral compounds may racemize at elevated temperatures or in the presence of base.

Why Buy cis-3-fluorocyclobutanamine hydrochloride From ChemContract?

Quality Assured

Every batch of cis-3-fluorocyclobutanamine hydrochloride is produced under cGMP conditions with full CoA documentation, HPLC purity verification, and lot traceability.

Fast USA Shipping

Ship from our Huntington Beach, CA facility with 2-3 business day domestic delivery. No import delays, no customs fees, no tariff surprises.

Custom Synthesis

Need a specific grade, quantity, or derivative of cis-3-fluorocyclobutanamine hydrochloride? Our team of PhD chemists can develop custom synthesis solutions for your exact requirements.

Frequently Asked

Common questions about cis-3-fluorocyclobutanamine hydrochloride

What is cis-3-fluorocyclobutanamine hydrochloride used for? +

cis-3-fluorocyclobutanamine hydrochloride is a fluorine-containing building block with enhanced metabolic stability used primarily in the pharmaceutical and diagnostic imaging industries. Key applications include metabolic blocking strategy — fluorine substitution to improve drug half-life and improved handling characteristics versus the free base form.

Where can I buy cis-3-fluorocyclobutanamine hydrochloride in the USA? +

ChemContract Research is a trusted USA-based supplier of cis-3-fluorocyclobutanamine hydrochloride. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.

What purity levels are available for cis-3-fluorocyclobutanamine hydrochloride? +

ChemContract Research supplies cis-3-fluorocyclobutanamine hydrochloride in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.

Can ChemContract synthesize cis-3-fluorocyclobutanamine hydrochloride in custom quantities? +

Yes. ChemContract Research offers custom synthesis services for cis-3-fluorocyclobutanamine hydrochloride from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.

Can I get cis-3-fluorocyclobutanamine hydrochloride in a different salt form or as the free base? +

Yes. ChemContract Research can supply cis-3-fluorocyclobutanamine hydrochloride as the free base or convert it to alternative salt forms including hydrochloride, mesylate, tosylate, fumarate, or other pharmaceutically acceptable counter-ions. Salt form selection impacts crystallinity, stability, and solubility — our chemistry team can advise on optimal salt selection for your application. Currently supplied as the Hydrochloride form.

What is the stereochemical purity of cis-3-fluorocyclobutanamine hydrochloride? +

ChemContract Research supplies cis-3-fluorocyclobutanamine hydrochloride with verified enantiomeric or diastereomeric purity as documented in our Certificate of Analysis (CoA). Chiral HPLC analysis is standard for stereodefined compounds. We can provide material with ≥98% ee/de for demanding applications. Contact us for specific optical purity requirements.

How should I store cis-3-fluorocyclobutanamine hydrochloride? +

Store at recommended temperature in a tightly sealed container. Protect from moisture, heat, and incompatible materials. Store at room temperature in a tightly sealed container. Protect from humidity. Store under recommended conditions. Some chiral compounds may racemize at elevated temperatures or in the presence of base. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.

What is the CAS number of cis-3-fluorocyclobutanamine hydrochloride? +

The CAS Registry Number for cis-3-fluorocyclobutanamine hydrochloride is 1408075-13-7. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.

Chemical analysis laboratory with HPLC instruments for purity and impurity testing Custom chemical synthesis reaction setup for pharmaceutical intermediate production

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