cis-3-benzylaminocyclobutanecarboxylic acid tfa (1:1)

cis-3-benzylaminocyclobutanecarboxylic acid tfa (1:1) is an amine-functionalized compound with nucleophilic nitrogen reactivity used primarily in the pharmaceutical and polymer industries. Key applications include buchwald–hartwig amination for aryl c–n bond construction and amide bond formation via edc/hobt or hatu coupling in peptide synthesis.

ChemContract Research is a trusted USA-based supplier of cis-3-benzylaminocyclobutanecarboxylic acid tfa (1:1). We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.

ChemContract Research supplies cis-3-benzylaminocyclobutanecarboxylic acid tfa (1:1) in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.

Yes. ChemContract Research offers custom synthesis services for cis-3-benzylaminocyclobutanecarboxylic acid tfa (1:1) from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.

For amide bond formation from the carboxylic acid in cis-3-benzylaminocyclobutanecarboxylic acid tfa (1:1), HATU/DIPEA is recommended for peptide coupling (high yield, low epimerization). EDC/HOBt is a cost-effective alternative for non-peptide amides. T3P (propylphosphonic acid anhydride) offers excellent atom economy with easy workup. For ester formation, DCC/DMAP (Steglich conditions) or Mitsunobu conditions are standard.

The amine functionality in cis-3-benzylaminocyclobutanecarboxylic acid tfa (1:1) enables diverse transformations: reductive amination with aldehydes/ketones, acylation to form amides, sulfonylation to form sulfonamides, Buchwald–Hartwig coupling with aryl halides, urea and carbamate formation, and salt generation for improved drug properties. The nucleophilicity of the nitrogen makes it one of the most versatile handles in synthetic chemistry.

Store in a cool, well-ventilated area away from acids and oxidizing agents. Keep containers tightly sealed as many amines are hygroscopic. Store at room temperature in a tightly sealed container. Protect from moisture and strong bases. Store under recommended conditions. Some chiral compounds may racemize at elevated temperatures or in the presence of base. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.

The CAS Registry Number for cis-3-benzylaminocyclobutanecarboxylic acid tfa (1:1) is 1523571-21-2. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.