Search 7,000+ Chemicals

Start typing to search our catalog

benzyl cis-2-aminocyclobutane-1-carboxylate; trifluoroacetic acid

Amine · 5 functional traits · cGMP compliant · Ships from USA in 2-3 days

Amine

benzyl cis-2-aminocyclobutane-1-carboxylate; trifluoroacetic acid

Fluorinated PharmaceuticalPolymerAgrochemicalCatalysisDiagnostic ImagingMaterials Science
Category Amine · Fluorinated Compound
Origin USA
Compliance cGMP

Questions? Contact our chemistry team:

chemistry@chem-contract.com | +1 (714) 732-8549
In stock — typically ships within 2-3 business days

About benzyl cis-2-aminocyclobutane-1-carboxylate; trifluoroacetic acid

benzyl cis-2-aminocyclobutane-1-carboxylate; trifluoroacetic acid is an amine-functionalized compound with nucleophilic nitrogen reactivity featuring a Cyclobutane ring with defined stereochemistry. ChemContract Research supplies this moderate-complexity compound in high purity from our Huntington Beach, California facility, ensuring consistent quality and reliable domestic delivery throughout the United States. Supplied as the trifluoroacetate salt form for enhanced stability and handling.

Amines are among the most prevalent functional groups in drug molecules — over 80% of small-molecule pharmaceuticals contain at least one amine moiety. The carbon–fluorine bond is the strongest single bond to carbon (485 kJ/mol). This exceptional stability underpins the "fluorine scan" strategy used in medicinal chemistry to optimize drug candidates. Carboxylic acids are among the most synthetically versatile functional groups — they can be converted to amides, esters, acid chlorides, anhydrides, alcohols, and aldehydes in a single step.

Primary applications include buchwald–hartwig amination for aryl c–n bond construction and metabolic blocking strategy — fluorine substitution to improve drug half-life. This compound serves researchers and manufacturers across the pharmaceutical, polymer, agrochemical sectors. Whether you require benzyl cis-2-aminocyclobutane-1-carboxylate; trifluoroacetic acid for early-stage research, process development, or commercial-scale production, ChemContract Research offers flexible ordering from milligram to multi-kilogram quantities with custom synthesis options and full batch documentation including Certificates of Analysis (CoA) and Safety Data Sheets.

Ring Systems: Cyclobutane
Functional Groups: Amine (–NH₂/–NHR)Carboxylic acid (–COOH)Fluorine (C–F)
Stereochemistry: Defined Configuration
Salt Form: Trifluoroacetate

Amine Applications & Target Industries

How benzyl cis-2-aminocyclobutane-1-carboxylate; trifluoroacetic acid is used across pharmaceutical and polymer sectors

01

Buchwald–Hartwig amination for aryl C–N bond construction

02

Metabolic blocking strategy — fluorine substitution to improve drug half-life

03

Amide bond formation via EDC/HOBt or HATU coupling in peptide synthesis

04

Commonly isolated form from Boc deprotection in peptide synthesis

05

Enantiopure building block for single-enantiomer drug development

06

Reductive amination with aldehydes and ketones for secondary amine synthesis

Target Industries: PharmaceuticalPolymerAgrochemicalCatalysisDiagnostic ImagingMaterials Science

benzyl cis-2-aminocyclobutane-1-carboxylate; trifluoroacetic acid Specifications

Detailed specifications for this amine, including purity, molecular weight, and analytical data are available upon request. Every batch from ChemContract Research includes:

  • Certificate of Analysis (CoA) with purity verification
  • HPLC, NMR, and/or mass spectrometry characterization data
  • Material Safety Data Sheet (MSDS/SDS)
  • Batch-specific documentation and lot traceability
  • Custom analytical testing available on request
Request Full Specifications

Quick Reference

Compound Name benzyl cis-2-aminocyclobutane-1-carboxylate; trifluoroacetic acid
Type Amine
Category Amine · Fluorinated Compound
Purity ≥95% (custom grades available)
Stereochemistry Defined configuration (chiral HPLC verified)
Salt Form Trifluoroacetate
Complexity Moderate (3 functional groups, 1 ring)
Compliance cGMP
Packaging mg to kg scale

Storage & Handling for Amines

Handling Guidelines

Amines may have strong odors and can be corrosive to skin. Handle under adequate ventilation with chemical-resistant gloves and eye protection. Handle with care in a well-ventilated fume hood. Some fluorinated compounds may release HF upon decomposition. Use chemical-resistant gloves. Acids may be corrosive or irritating. Handle with chemical-resistant gloves and eye protection. Use a fume hood for volatile acids. TFA salts are hygroscopic. Handle in a dry environment. TFA is corrosive — wear chemical-resistant gloves. Handle with standard precautions. Ensure proper labeling of stereochemical identity to prevent mix-ups.

Storage Conditions

Store in a cool, well-ventilated area away from acids and oxidizing agents. Keep containers tightly sealed as many amines are hygroscopic. Store at recommended temperature in a tightly sealed container. Protect from moisture, heat, and incompatible materials. Store at room temperature in a tightly sealed container. Protect from moisture and strong bases. Store desiccated at –20 °C or as recommended. Protect from moisture to prevent deliquescence. Store under recommended conditions. Some chiral compounds may racemize at elevated temperatures or in the presence of base.

Why Buy benzyl cis-2-aminocyclobutane-1-carboxylate; trifluoroacetic acid From ChemContract?

Quality Assured

Every batch of benzyl cis-2-aminocyclobutane-1-carboxylate; trifluoroacetic acid is produced under cGMP conditions with full CoA documentation, HPLC purity verification, and lot traceability.

Fast USA Shipping

Ship from our Huntington Beach, CA facility with 2-3 business day domestic delivery. No import delays, no customs fees, no tariff surprises.

Custom Synthesis

Need a specific grade, quantity, or derivative of benzyl cis-2-aminocyclobutane-1-carboxylate; trifluoroacetic acid? Our team of PhD chemists can develop custom synthesis solutions for your exact requirements.

Frequently Asked

Common questions about benzyl cis-2-aminocyclobutane-1-carboxylate; trifluoroacetic acid

What is benzyl cis-2-aminocyclobutane-1-carboxylate; trifluoroacetic acid used for? +

benzyl cis-2-aminocyclobutane-1-carboxylate; trifluoroacetic acid is an amine-functionalized compound with nucleophilic nitrogen reactivity used primarily in the pharmaceutical and polymer industries. Key applications include buchwald–hartwig amination for aryl c–n bond construction and metabolic blocking strategy — fluorine substitution to improve drug half-life.

Where can I buy benzyl cis-2-aminocyclobutane-1-carboxylate; trifluoroacetic acid in the USA? +

ChemContract Research is a trusted USA-based supplier of benzyl cis-2-aminocyclobutane-1-carboxylate; trifluoroacetic acid. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.

What purity levels are available for benzyl cis-2-aminocyclobutane-1-carboxylate; trifluoroacetic acid? +

ChemContract Research supplies benzyl cis-2-aminocyclobutane-1-carboxylate; trifluoroacetic acid in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.

Can ChemContract synthesize benzyl cis-2-aminocyclobutane-1-carboxylate; trifluoroacetic acid in custom quantities? +

Yes. ChemContract Research offers custom synthesis services for benzyl cis-2-aminocyclobutane-1-carboxylate; trifluoroacetic acid from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.

What coupling reagents work best with benzyl cis-2-aminocyclobutane-1-carboxylate; trifluoroacetic acid? +

For amide bond formation from the carboxylic acid in benzyl cis-2-aminocyclobutane-1-carboxylate; trifluoroacetic acid, HATU/DIPEA is recommended for peptide coupling (high yield, low epimerization). EDC/HOBt is a cost-effective alternative for non-peptide amides. T3P (propylphosphonic acid anhydride) offers excellent atom economy with easy workup. For ester formation, DCC/DMAP (Steglich conditions) or Mitsunobu conditions are standard.

Can I get benzyl cis-2-aminocyclobutane-1-carboxylate; trifluoroacetic acid in a different salt form or as the free base? +

Yes. ChemContract Research can supply benzyl cis-2-aminocyclobutane-1-carboxylate; trifluoroacetic acid as the free base or convert it to alternative salt forms including hydrochloride, mesylate, tosylate, fumarate, or other pharmaceutically acceptable counter-ions. Salt form selection impacts crystallinity, stability, and solubility — our chemistry team can advise on optimal salt selection for your application. Currently supplied as the Trifluoroacetate form.

How should I store benzyl cis-2-aminocyclobutane-1-carboxylate; trifluoroacetic acid? +

Store in a cool, well-ventilated area away from acids and oxidizing agents. Keep containers tightly sealed as many amines are hygroscopic. Store at recommended temperature in a tightly sealed container. Protect from moisture, heat, and incompatible materials. Store at room temperature in a tightly sealed container. Protect from moisture and strong bases. Store desiccated at –20 °C or as recommended. Protect from moisture to prevent deliquescence. Store under recommended conditions. Some chiral compounds may racemize at elevated temperatures or in the presence of base. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.

Chemical analysis laboratory with HPLC instruments for purity and impurity testing Custom chemical synthesis reaction setup for pharmaceutical intermediate production

Get benzyl cis-2-aminocyclobutane-1-carboxylate; trifluoroacetic acid Delivered This Week

Get competitive pricing, custom quantities, and fast USA delivery. Our chemistry team is standing by to provide specifications, CoA documentation, and a tailored quote for your project.

Or call us directly: +1 (714) 732-8549

ChemContract

Let's Build
Your Molecule

From discovery to commercial scale — our 500+ scientists are ready to accelerate your project.

24-Hour ResponseFast turnaround guaranteed
60+ FacilitiesGlobal R&D network
cGMP CompliantFDA-ready manufacturing

Request a Quote

Tell us about your compound and we'll send a detailed quote within 24 hours.

Contact Information
Chemical Specifications
ChemContract
Mon-Fri 8AM-5PM PT

Hi there! How can we help you today?