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Azetidine-3-carboxylic acid methyl ester hydrochloride, 97%

CAS 100202-39-9 · Carboxylic Acid · 3 functional traits · cGMP compliant · Ships from USA in 2-3 days

Carboxylic Acid

Azetidine-3-carboxylic acid methyl ester hydrochloride, 97%

Heterocycles PharmaceuticalPolymerFine ChemicalAgrochemicalGreen ChemistryFormulation
CAS Number 100202-39-9
Category Carboxylic Acid · Ester
Origin USA
Compliance cGMP

Questions? Contact our chemistry team:

chemistry@chem-contract.com | +1 (714) 732-8549
In stock — typically ships within 2-3 business days

About Azetidine-3-carboxylic acid methyl ester hydrochloride, 97%

Azetidine-3-carboxylic acid methyl ester hydrochloride, 97% (CAS Number: 100202-39-9) is a carboxylic acid that participates in diverse condensation and coupling reactions featuring a Azetidine ring. ChemContract Research supplies this moderate-complexity compound in high purity from our Huntington Beach, California facility, ensuring consistent quality and reliable domestic delivery throughout the United States. Supplied as the hydrochloride salt form for enhanced stability and handling.

Carboxylic acids are among the most synthetically versatile functional groups — they can be converted to amides, esters, acid chlorides, anhydrides, alcohols, and aldehydes in a single step. Ester hydrolysis by cellular esterases is the most commonly exploited prodrug activation mechanism — enabling drugs that cannot cross biological membranes as free acids. Hydrochloride is the most common salt form for basic drug substances — approximately half of all salt-form drugs on the market are HCl salts, valued for their crystallinity and aqueous solubility.

Primary applications include amide bond formation via edc/hobt or hatu coupling in peptide synthesis and prodrug development to mask carboxylic acids and improve membrane permeability. This compound serves researchers and manufacturers across the pharmaceutical, polymer, fine chemical sectors. Whether you require Azetidine-3-carboxylic acid methyl ester hydrochloride, 97% for early-stage research, process development, or commercial-scale production, ChemContract Research offers flexible ordering from milligram to multi-kilogram quantities with custom synthesis options and full batch documentation including Certificates of Analysis (CoA) and Safety Data Sheets.

Ring Systems: Azetidine
Functional Groups: Carboxylic acid (–COOH)Ester (–COOR)Chlorine (C–Cl)
Salt Form: Hydrochloride

Carboxylic Acid Applications & Target Industries

How Azetidine-3-carboxylic acid methyl ester hydrochloride, 97% is used across pharmaceutical and polymer sectors

01

Amide bond formation via EDC/HOBt or HATU coupling in peptide synthesis

02

Prodrug development to mask carboxylic acids and improve membrane permeability

03

Improved handling characteristics versus the free base form

04

Salt formation with amines to improve drug crystallinity and stability

05

Protecting group for hydroxyl functionalities (acetate, benzoate)

06

Direct formulation excipient in oral solid dosage forms

Target Industries: PharmaceuticalPolymerFine ChemicalAgrochemicalGreen ChemistryFormulation

Azetidine-3-carboxylic acid methyl ester hydrochloride, 97% Specifications

Detailed specifications for this carboxylic acid, including purity, molecular weight, and analytical data are available upon request. Every batch from ChemContract Research includes:

  • Certificate of Analysis (CoA) with purity verification
  • HPLC, NMR, and/or mass spectrometry characterization data
  • Material Safety Data Sheet (MSDS/SDS)
  • Batch-specific documentation and lot traceability
  • Custom analytical testing available on request
Request Full Specifications

Quick Reference

Compound Name Azetidine-3-carboxylic acid methyl ester hydrochloride, 97%
Type Carboxylic Acid
Category Carboxylic Acid · Ester
Purity ≥95% (custom grades available)
Salt Form Hydrochloride
Complexity Moderate (3 functional groups, 1 ring)
Compliance cGMP
Packaging mg to kg scale

Storage & Handling for Carboxylic Acids

Handling Guidelines

Acids may be corrosive or irritating. Handle with chemical-resistant gloves and eye protection. Use a fume hood for volatile acids. Some esters are volatile and flammable. Handle in a well-ventilated area. Keep away from ignition sources. Handle with standard precautions. Hydrochloride salts are generally more stable than free bases.

Storage Conditions

Store at room temperature in a tightly sealed container. Protect from moisture and strong bases. Store at room temperature in a tightly sealed container away from heat and open flame. Store at room temperature in a tightly sealed container. Protect from humidity.

Why Buy Azetidine-3-carboxylic acid methyl ester hydrochloride, 97% From ChemContract?

Quality Assured

Every batch of Azetidine-3-carboxylic acid methyl ester hydrochloride, 97% is produced under cGMP conditions with full CoA documentation, HPLC purity verification, and lot traceability.

Fast USA Shipping

Ship from our Huntington Beach, CA facility with 2-3 business day domestic delivery. No import delays, no customs fees, no tariff surprises.

Custom Synthesis

Need a specific grade, quantity, or derivative of Azetidine-3-carboxylic acid methyl ester hydrochloride, 97%? Our team of PhD chemists can develop custom synthesis solutions for your exact requirements.

Frequently Asked

Common questions about Azetidine-3-carboxylic acid methyl ester hydrochloride, 97%

What is Azetidine-3-carboxylic acid methyl ester hydrochloride, 97% used for? +

Azetidine-3-carboxylic acid methyl ester hydrochloride, 97% is a carboxylic acid that participates in diverse condensation and coupling reactions used primarily in the pharmaceutical and polymer industries. Key applications include amide bond formation via edc/hobt or hatu coupling in peptide synthesis and prodrug development to mask carboxylic acids and improve membrane permeability.

Where can I buy Azetidine-3-carboxylic acid methyl ester hydrochloride, 97% in the USA? +

ChemContract Research is a trusted USA-based supplier of Azetidine-3-carboxylic acid methyl ester hydrochloride, 97%. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.

What purity levels are available for Azetidine-3-carboxylic acid methyl ester hydrochloride, 97%? +

ChemContract Research supplies Azetidine-3-carboxylic acid methyl ester hydrochloride, 97% in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.

Can ChemContract synthesize Azetidine-3-carboxylic acid methyl ester hydrochloride, 97% in custom quantities? +

Yes. ChemContract Research offers custom synthesis services for Azetidine-3-carboxylic acid methyl ester hydrochloride, 97% from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.

Can I get Azetidine-3-carboxylic acid methyl ester hydrochloride, 97% in a different salt form or as the free base? +

Yes. ChemContract Research can supply Azetidine-3-carboxylic acid methyl ester hydrochloride, 97% as the free base or convert it to alternative salt forms including hydrochloride, mesylate, tosylate, fumarate, or other pharmaceutically acceptable counter-ions. Salt form selection impacts crystallinity, stability, and solubility — our chemistry team can advise on optimal salt selection for your application. Currently supplied as the Hydrochloride form.

What coupling reagents work best with Azetidine-3-carboxylic acid methyl ester hydrochloride, 97%? +

For amide bond formation from the carboxylic acid in Azetidine-3-carboxylic acid methyl ester hydrochloride, 97%, HATU/DIPEA is recommended for peptide coupling (high yield, low epimerization). EDC/HOBt is a cost-effective alternative for non-peptide amides. T3P (propylphosphonic acid anhydride) offers excellent atom economy with easy workup. For ester formation, DCC/DMAP (Steglich conditions) or Mitsunobu conditions are standard.

How should I store Azetidine-3-carboxylic acid methyl ester hydrochloride, 97%? +

Store at room temperature in a tightly sealed container. Protect from moisture and strong bases. Store at room temperature in a tightly sealed container away from heat and open flame. Store at room temperature in a tightly sealed container. Protect from humidity. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.

What is the CAS number of Azetidine-3-carboxylic acid methyl ester hydrochloride, 97%? +

The CAS Registry Number for Azetidine-3-carboxylic acid methyl ester hydrochloride, 97% is 100202-39-9. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.

Chemical analysis laboratory with HPLC instruments for purity and impurity testing Custom chemical synthesis reaction setup for pharmaceutical intermediate production

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