Fluorinated Compound · 3 functional traits · cGMP compliant · Ships from USA in 2-3 days
7-Fluoroindole-3-carboxylic acid 7-Fluoro-1H-indole-3-carboxylic acid is a fluorine-containing building block with enhanced metabolic stability featuring a Indole ring. ChemContract Research supplies this moderate-complexity compound in high purity from our Huntington Beach, California facility, ensuring consistent quality and reliable domestic delivery throughout the United States.
The carbon–fluorine bond is the strongest single bond to carbon (485 kJ/mol). This exceptional stability underpins the "fluorine scan" strategy used in medicinal chemistry to optimize drug candidates. Heterocyclic rings appear in approximately 85% of all biologically active compounds. The nitrogen, oxygen, or sulfur heteroatom modulates electron density, hydrogen bonding, and aqueous solubility. Carboxylic acids are among the most synthetically versatile functional groups — they can be converted to amides, esters, acid chlorides, anhydrides, alcohols, and aldehydes in a single step.
Primary applications include metabolic blocking strategy — fluorine substitution to improve drug half-life and core scaffold in kinase inhibitor design for oncology therapeutics. This compound serves researchers and manufacturers across the pharmaceutical, diagnostic imaging, agrochemical sectors. Whether you require 7-Fluoroindole-3-carboxylic acid 7-Fluoro-1H-indole-3-carboxylic acid for early-stage research, process development, or commercial-scale production, ChemContract Research offers flexible ordering from milligram to multi-kilogram quantities with custom synthesis options and full batch documentation including Certificates of Analysis (CoA) and Safety Data Sheets.
How 7-Fluoroindole-3-carboxylic acid 7-Fluoro-1H-indole-3-carboxylic acid is used across pharmaceutical and diagnostic imaging sectors
Metabolic blocking strategy — fluorine substitution to improve drug half-life
Core scaffold in kinase inhibitor design for oncology therapeutics
Amide bond formation via EDC/HOBt or HATU coupling in peptide synthesis
PET radiotracer precursor ([¹⁸F]-labeling) for diagnostic imaging
GPCR modulator development for CNS and cardiovascular indications
Salt formation with amines to improve drug crystallinity and stability
Detailed specifications for this fluorinated compound, including purity, molecular weight, and analytical data are available upon request. Every batch from ChemContract Research includes:
Handle with care in a well-ventilated fume hood. Some fluorinated compounds may release HF upon decomposition. Use chemical-resistant gloves. Handle with standard laboratory precautions. Some heterocycles may be hygroscopic or irritating. Use adequate ventilation. Acids may be corrosive or irritating. Handle with chemical-resistant gloves and eye protection. Use a fume hood for volatile acids.
Store at recommended temperature in a tightly sealed container. Protect from moisture, heat, and incompatible materials. Store at recommended temperature in a tightly sealed container. Some heterocyclic compounds are light-sensitive. Store at room temperature in a tightly sealed container. Protect from moisture and strong bases.
Fluorinated compounds require careful handling. We provide 7-Fluoroindole-3-carboxylic acid 7-Fluoro-1H-indole-3-carboxylic acid with verified fluorine content, stability data, and guidance on storage to prevent decomposition.
Every batch of 7-Fluoroindole-3-carboxylic acid 7-Fluoro-1H-indole-3-carboxylic acid is produced under cGMP conditions with full CoA documentation, HPLC purity verification, and lot traceability.
Ship from our Huntington Beach, CA facility with 2-3 business day domestic delivery. No import delays, no customs fees, no tariff surprises.
Need a specific grade, quantity, or derivative of 7-Fluoroindole-3-carboxylic acid 7-Fluoro-1H-indole-3-carboxylic acid? Our team of PhD chemists can develop custom synthesis solutions for your exact requirements.
Common questions about 7-Fluoroindole-3-carboxylic acid 7-Fluoro-1H-indole-3-carboxylic acid
7-Fluoroindole-3-carboxylic acid 7-Fluoro-1H-indole-3-carboxylic acid is a fluorine-containing building block with enhanced metabolic stability used primarily in the pharmaceutical and diagnostic imaging industries. Key applications include metabolic blocking strategy — fluorine substitution to improve drug half-life and core scaffold in kinase inhibitor design for oncology therapeutics.
ChemContract Research is a trusted USA-based supplier of 7-Fluoroindole-3-carboxylic acid 7-Fluoro-1H-indole-3-carboxylic acid. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.
ChemContract Research supplies 7-Fluoroindole-3-carboxylic acid 7-Fluoro-1H-indole-3-carboxylic acid in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.
Yes. ChemContract Research offers custom synthesis services for 7-Fluoroindole-3-carboxylic acid 7-Fluoro-1H-indole-3-carboxylic acid from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.
The fluorine atom(s) in 7-Fluoroindole-3-carboxylic acid 7-Fluoro-1H-indole-3-carboxylic acid confer several advantages in drug design: increased metabolic stability due to the strong C–F bond (485 kJ/mol), enhanced lipophilicity for improved membrane permeability, and potential for favorable electrostatic interactions with biological targets. These properties make fluorinated compounds like 7-Fluoroindole-3-carboxylic acid 7-Fluoro-1H-indole-3-carboxylic acid valuable in pharmaceutical development.
The Indole ring system(s) in 7-Fluoroindole-3-carboxylic acid 7-Fluoro-1H-indole-3-carboxylic acid is a privileged structure in medicinal chemistry, appearing in numerous FDA-approved drugs. This scaffold is commonly used in kinase inhibitor design, GPCR modulator development, and lead optimization programs. ChemContract supplies this building block for early-stage discovery through process-scale manufacturing.
Store at recommended temperature in a tightly sealed container. Protect from moisture, heat, and incompatible materials. Store at recommended temperature in a tightly sealed container. Some heterocyclic compounds are light-sensitive. Store at room temperature in a tightly sealed container. Protect from moisture and strong bases. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.
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