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7-Fluoro-1H-indole-3-carbaldehyde 1H-Indole-3-carboxaldehyde, 7-fluoro-

Aldehyde · 3 functional traits · cGMP compliant · Ships from USA in 2-3 days

Aldehyde

7-Fluoro-1H-indole-3-carbaldehyde 1H-Indole-3-carboxaldehyde, 7-fluoro-

Fluorinated PharmaceuticalFragrance & FlavorFine ChemicalResearchDiagnostic ImagingAgrochemical
Category Aldehyde · Fluorinated Compound
Origin USA
Compliance cGMP

Questions? Contact our chemistry team:

chemistry@chem-contract.com | +1 (714) 732-8549
In stock — typically ships within 2-3 business days

About 7-Fluoro-1H-indole-3-carbaldehyde 1H-Indole-3-carboxaldehyde, 7-fluoro-

7-Fluoro-1H-indole-3-carbaldehyde 1H-Indole-3-carboxaldehyde, 7-fluoro- is an aldehyde with a highly electrophilic carbonyl group featuring a Indole ring. ChemContract Research supplies this moderate-complexity compound in high purity from our Huntington Beach, California facility, ensuring consistent quality and reliable domestic delivery throughout the United States.

The aldehyde carbonyl is one of the most reactive electrophilic centers in organic chemistry, enabling diverse transformations from imine formation to asymmetric allylation. The carbon–fluorine bond is the strongest single bond to carbon (485 kJ/mol). This exceptional stability underpins the "fluorine scan" strategy used in medicinal chemistry to optimize drug candidates. Heterocyclic rings appear in approximately 85% of all biologically active compounds. The nitrogen, oxygen, or sulfur heteroatom modulates electron density, hydrogen bonding, and aqueous solubility.

Primary applications include reductive amination for c–n bond formation in api synthesis and metabolic blocking strategy — fluorine substitution to improve drug half-life. This compound serves researchers and manufacturers across the pharmaceutical, fragrance & flavor, fine chemical sectors. Whether you require 7-Fluoro-1H-indole-3-carbaldehyde 1H-Indole-3-carboxaldehyde, 7-fluoro- for early-stage research, process development, or commercial-scale production, ChemContract Research offers flexible ordering from milligram to multi-kilogram quantities with custom synthesis options and full batch documentation including Certificates of Analysis (CoA) and Safety Data Sheets.

Ring Systems: Indole
Functional Groups: Aldehyde (–CHO)Fluorine (C–F)

Aldehyde Applications & Target Industries

How 7-Fluoro-1H-indole-3-carbaldehyde 1H-Indole-3-carboxaldehyde, 7-fluoro- is used across pharmaceutical and fragrance & flavor sectors

01

Reductive amination for C–N bond formation in API synthesis

02

Metabolic blocking strategy — fluorine substitution to improve drug half-life

03

Core scaffold in kinase inhibitor design for oncology therapeutics

04

Wittig and Horner–Wadsworth–Emmons olefination substrates

05

PET radiotracer precursor ([¹⁸F]-labeling) for diagnostic imaging

06

GPCR modulator development for CNS and cardiovascular indications

Target Industries: PharmaceuticalFragrance & FlavorFine ChemicalResearchDiagnostic ImagingAgrochemical

7-Fluoro-1H-indole-3-carbaldehyde 1H-Indole-3-carboxaldehyde, 7-fluoro- Specifications

Detailed specifications for this aldehyde, including purity, molecular weight, and analytical data are available upon request. Every batch from ChemContract Research includes:

  • Certificate of Analysis (CoA) with purity verification
  • HPLC, NMR, and/or mass spectrometry characterization data
  • Material Safety Data Sheet (MSDS/SDS)
  • Batch-specific documentation and lot traceability
  • Custom analytical testing available on request
Request Full Specifications

Quick Reference

Compound Name 7-Fluoro-1H-indole-3-carbaldehyde 1H-Indole-3-carboxaldehyde, 7-fluoro-
Type Aldehyde
Category Aldehyde · Fluorinated Compound
Purity ≥95% (custom grades available)
Complexity Moderate (2 functional groups, 1 ring)
Compliance cGMP
Packaging mg to kg scale

Storage & Handling for Aldehydes

Handling Guidelines

Aldehydes can be irritating to skin, eyes, and respiratory tract. Handle in a well-ventilated fume hood. Many are volatile and flammable. Handle with care in a well-ventilated fume hood. Some fluorinated compounds may release HF upon decomposition. Use chemical-resistant gloves. Handle with standard laboratory precautions. Some heterocycles may be hygroscopic or irritating. Use adequate ventilation.

Storage Conditions

Store at recommended temperature under inert atmosphere. Protect from air to prevent oxidation to the corresponding carboxylic acid. Store at recommended temperature in a tightly sealed container. Protect from moisture, heat, and incompatible materials. Store at recommended temperature in a tightly sealed container. Some heterocyclic compounds are light-sensitive.

Why Buy 7-Fluoro-1H-indole-3-carbaldehyde 1H-Indole-3-carboxaldehyde, 7-fluoro- From ChemContract?

Quality Assured

Every batch of 7-Fluoro-1H-indole-3-carbaldehyde 1H-Indole-3-carboxaldehyde, 7-fluoro- is produced under cGMP conditions with full CoA documentation, HPLC purity verification, and lot traceability.

Fast USA Shipping

Ship from our Huntington Beach, CA facility with 2-3 business day domestic delivery. No import delays, no customs fees, no tariff surprises.

Custom Synthesis

Need a specific grade, quantity, or derivative of 7-Fluoro-1H-indole-3-carbaldehyde 1H-Indole-3-carboxaldehyde, 7-fluoro-? Our team of PhD chemists can develop custom synthesis solutions for your exact requirements.

Frequently Asked

Common questions about 7-Fluoro-1H-indole-3-carbaldehyde 1H-Indole-3-carboxaldehyde, 7-fluoro-

What is 7-Fluoro-1H-indole-3-carbaldehyde 1H-Indole-3-carboxaldehyde, 7-fluoro- used for? +

7-Fluoro-1H-indole-3-carbaldehyde 1H-Indole-3-carboxaldehyde, 7-fluoro- is an aldehyde with a highly electrophilic carbonyl group used primarily in the pharmaceutical and fragrance & flavor industries. Key applications include reductive amination for c–n bond formation in api synthesis and metabolic blocking strategy — fluorine substitution to improve drug half-life.

Where can I buy 7-Fluoro-1H-indole-3-carbaldehyde 1H-Indole-3-carboxaldehyde, 7-fluoro- in the USA? +

ChemContract Research is a trusted USA-based supplier of 7-Fluoro-1H-indole-3-carbaldehyde 1H-Indole-3-carboxaldehyde, 7-fluoro-. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.

What purity levels are available for 7-Fluoro-1H-indole-3-carbaldehyde 1H-Indole-3-carboxaldehyde, 7-fluoro-? +

ChemContract Research supplies 7-Fluoro-1H-indole-3-carbaldehyde 1H-Indole-3-carboxaldehyde, 7-fluoro- in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.

Can ChemContract synthesize 7-Fluoro-1H-indole-3-carbaldehyde 1H-Indole-3-carboxaldehyde, 7-fluoro- in custom quantities? +

Yes. ChemContract Research offers custom synthesis services for 7-Fluoro-1H-indole-3-carbaldehyde 1H-Indole-3-carboxaldehyde, 7-fluoro- from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.

Why is fluorine important in 7-Fluoro-1H-indole-3-carbaldehyde 1H-Indole-3-carboxaldehyde, 7-fluoro-? +

The fluorine atom(s) in 7-Fluoro-1H-indole-3-carbaldehyde 1H-Indole-3-carboxaldehyde, 7-fluoro- confer several advantages in drug design: increased metabolic stability due to the strong C–F bond (485 kJ/mol), enhanced lipophilicity for improved membrane permeability, and potential for favorable electrostatic interactions with biological targets. These properties make fluorinated compounds like 7-Fluoro-1H-indole-3-carbaldehyde 1H-Indole-3-carboxaldehyde, 7-fluoro- valuable in pharmaceutical development.

What drug discovery applications use 7-Fluoro-1H-indole-3-carbaldehyde 1H-Indole-3-carboxaldehyde, 7-fluoro-? +

The Indole ring system(s) in 7-Fluoro-1H-indole-3-carbaldehyde 1H-Indole-3-carboxaldehyde, 7-fluoro- is a privileged structure in medicinal chemistry, appearing in numerous FDA-approved drugs. This scaffold is commonly used in kinase inhibitor design, GPCR modulator development, and lead optimization programs. ChemContract supplies this building block for early-stage discovery through process-scale manufacturing.

How should I store 7-Fluoro-1H-indole-3-carbaldehyde 1H-Indole-3-carboxaldehyde, 7-fluoro-? +

Store at recommended temperature under inert atmosphere. Protect from air to prevent oxidation to the corresponding carboxylic acid. Store at recommended temperature in a tightly sealed container. Protect from moisture, heat, and incompatible materials. Store at recommended temperature in a tightly sealed container. Some heterocyclic compounds are light-sensitive. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.

Chemical analysis laboratory with HPLC instruments for purity and impurity testing Custom chemical synthesis reaction setup for pharmaceutical intermediate production

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Get competitive pricing, custom quantities, and fast USA delivery. Our chemistry team is standing by to provide specifications, CoA documentation, and a tailored quote for your project.

Or call us directly: +1 (714) 732-8549

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