Aldehyde · 3 functional traits · cGMP compliant · Ships from USA in 2-3 days
7-Fluoro-1H-indole-3-carbaldehyde 1H-Indole-3-carboxaldehyde, 7-fluoro- is an aldehyde with a highly electrophilic carbonyl group featuring a Indole ring. ChemContract Research supplies this moderate-complexity compound in high purity from our Huntington Beach, California facility, ensuring consistent quality and reliable domestic delivery throughout the United States.
The aldehyde carbonyl is one of the most reactive electrophilic centers in organic chemistry, enabling diverse transformations from imine formation to asymmetric allylation. The carbon–fluorine bond is the strongest single bond to carbon (485 kJ/mol). This exceptional stability underpins the "fluorine scan" strategy used in medicinal chemistry to optimize drug candidates. Heterocyclic rings appear in approximately 85% of all biologically active compounds. The nitrogen, oxygen, or sulfur heteroatom modulates electron density, hydrogen bonding, and aqueous solubility.
Primary applications include reductive amination for c–n bond formation in api synthesis and metabolic blocking strategy — fluorine substitution to improve drug half-life. This compound serves researchers and manufacturers across the pharmaceutical, fragrance & flavor, fine chemical sectors. Whether you require 7-Fluoro-1H-indole-3-carbaldehyde 1H-Indole-3-carboxaldehyde, 7-fluoro- for early-stage research, process development, or commercial-scale production, ChemContract Research offers flexible ordering from milligram to multi-kilogram quantities with custom synthesis options and full batch documentation including Certificates of Analysis (CoA) and Safety Data Sheets.
How 7-Fluoro-1H-indole-3-carbaldehyde 1H-Indole-3-carboxaldehyde, 7-fluoro- is used across pharmaceutical and fragrance & flavor sectors
Reductive amination for C–N bond formation in API synthesis
Metabolic blocking strategy — fluorine substitution to improve drug half-life
Core scaffold in kinase inhibitor design for oncology therapeutics
Wittig and Horner–Wadsworth–Emmons olefination substrates
PET radiotracer precursor ([¹⁸F]-labeling) for diagnostic imaging
GPCR modulator development for CNS and cardiovascular indications
Detailed specifications for this aldehyde, including purity, molecular weight, and analytical data are available upon request. Every batch from ChemContract Research includes:
Aldehydes can be irritating to skin, eyes, and respiratory tract. Handle in a well-ventilated fume hood. Many are volatile and flammable. Handle with care in a well-ventilated fume hood. Some fluorinated compounds may release HF upon decomposition. Use chemical-resistant gloves. Handle with standard laboratory precautions. Some heterocycles may be hygroscopic or irritating. Use adequate ventilation.
Store at recommended temperature under inert atmosphere. Protect from air to prevent oxidation to the corresponding carboxylic acid. Store at recommended temperature in a tightly sealed container. Protect from moisture, heat, and incompatible materials. Store at recommended temperature in a tightly sealed container. Some heterocyclic compounds are light-sensitive.
Every batch of 7-Fluoro-1H-indole-3-carbaldehyde 1H-Indole-3-carboxaldehyde, 7-fluoro- is produced under cGMP conditions with full CoA documentation, HPLC purity verification, and lot traceability.
Ship from our Huntington Beach, CA facility with 2-3 business day domestic delivery. No import delays, no customs fees, no tariff surprises.
Need a specific grade, quantity, or derivative of 7-Fluoro-1H-indole-3-carbaldehyde 1H-Indole-3-carboxaldehyde, 7-fluoro-? Our team of PhD chemists can develop custom synthesis solutions for your exact requirements.
Common questions about 7-Fluoro-1H-indole-3-carbaldehyde 1H-Indole-3-carboxaldehyde, 7-fluoro-
7-Fluoro-1H-indole-3-carbaldehyde 1H-Indole-3-carboxaldehyde, 7-fluoro- is an aldehyde with a highly electrophilic carbonyl group used primarily in the pharmaceutical and fragrance & flavor industries. Key applications include reductive amination for c–n bond formation in api synthesis and metabolic blocking strategy — fluorine substitution to improve drug half-life.
ChemContract Research is a trusted USA-based supplier of 7-Fluoro-1H-indole-3-carbaldehyde 1H-Indole-3-carboxaldehyde, 7-fluoro-. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.
ChemContract Research supplies 7-Fluoro-1H-indole-3-carbaldehyde 1H-Indole-3-carboxaldehyde, 7-fluoro- in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.
Yes. ChemContract Research offers custom synthesis services for 7-Fluoro-1H-indole-3-carbaldehyde 1H-Indole-3-carboxaldehyde, 7-fluoro- from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.
The fluorine atom(s) in 7-Fluoro-1H-indole-3-carbaldehyde 1H-Indole-3-carboxaldehyde, 7-fluoro- confer several advantages in drug design: increased metabolic stability due to the strong C–F bond (485 kJ/mol), enhanced lipophilicity for improved membrane permeability, and potential for favorable electrostatic interactions with biological targets. These properties make fluorinated compounds like 7-Fluoro-1H-indole-3-carbaldehyde 1H-Indole-3-carboxaldehyde, 7-fluoro- valuable in pharmaceutical development.
The Indole ring system(s) in 7-Fluoro-1H-indole-3-carbaldehyde 1H-Indole-3-carboxaldehyde, 7-fluoro- is a privileged structure in medicinal chemistry, appearing in numerous FDA-approved drugs. This scaffold is commonly used in kinase inhibitor design, GPCR modulator development, and lead optimization programs. ChemContract supplies this building block for early-stage discovery through process-scale manufacturing.
Store at recommended temperature under inert atmosphere. Protect from air to prevent oxidation to the corresponding carboxylic acid. Store at recommended temperature in a tightly sealed container. Protect from moisture, heat, and incompatible materials. Store at recommended temperature in a tightly sealed container. Some heterocyclic compounds are light-sensitive. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.
Get competitive pricing, custom quantities, and fast USA delivery. Our chemistry team is standing by to provide specifications, CoA documentation, and a tailored quote for your project.
Or call us directly: +1 (714) 732-8549
Hi there! How can we help you today?