Frequently Asked
Common questions about 7-chloro-5-fluoro-2,3-dihydro-1H-indol-2-one
What is 7-chloro-5-fluoro-2,3-dihydro-1H-indol-2-one used for?
7-chloro-5-fluoro-2,3-dihydro-1H-indol-2-one is a fluorine-containing building block with enhanced metabolic stability used primarily in the pharmaceutical and diagnostic imaging industries. Key applications include metabolic blocking strategy — fluorine substitution to improve drug half-life and nucleophilic aromatic substitution (snar) for ether and amine formation.
Where can I buy 7-chloro-5-fluoro-2,3-dihydro-1H-indol-2-one in the USA?
ChemContract Research is a trusted USA-based supplier of 7-chloro-5-fluoro-2,3-dihydro-1H-indol-2-one. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.
What purity levels are available for 7-chloro-5-fluoro-2,3-dihydro-1H-indol-2-one?
ChemContract Research supplies 7-chloro-5-fluoro-2,3-dihydro-1H-indol-2-one in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.
Can ChemContract synthesize 7-chloro-5-fluoro-2,3-dihydro-1H-indol-2-one in custom quantities?
Yes. ChemContract Research offers custom synthesis services for 7-chloro-5-fluoro-2,3-dihydro-1H-indol-2-one from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.
Why is fluorine important in 7-chloro-5-fluoro-2,3-dihydro-1H-indol-2-one?
The fluorine atom(s) in 7-chloro-5-fluoro-2,3-dihydro-1H-indol-2-one confer several advantages in drug design: increased metabolic stability due to the strong C–F bond (485 kJ/mol), enhanced lipophilicity for improved membrane permeability, and potential for favorable electrostatic interactions with biological targets. These properties make fluorinated compounds like 7-chloro-5-fluoro-2,3-dihydro-1H-indol-2-one valuable in pharmaceutical development.
What is the stereochemical purity of 7-chloro-5-fluoro-2,3-dihydro-1H-indol-2-one?
ChemContract Research supplies 7-chloro-5-fluoro-2,3-dihydro-1H-indol-2-one with verified enantiomeric or diastereomeric purity as documented in our Certificate of Analysis (CoA). Chiral HPLC analysis is standard for stereodefined compounds. We can provide material with ≥98% ee/de for demanding applications. Contact us for specific optical purity requirements.
How should I store 7-chloro-5-fluoro-2,3-dihydro-1H-indol-2-one?
Store at recommended temperature in a tightly sealed container. Protect from moisture, heat, and incompatible materials. Store at recommended temperature in a well-sealed container. Protect from moisture and strong bases. Store under recommended conditions. Some chiral compounds may racemize at elevated temperatures or in the presence of base. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.
What is the CAS number of 7-chloro-5-fluoro-2,3-dihydro-1H-indol-2-one?
The CAS Registry Number for 7-chloro-5-fluoro-2,3-dihydro-1H-indol-2-one is 1260892-91-8. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.
