Frequently Asked
Common questions about 6-Hydroxymethyl-nicotinic acid methyl ester
What is 6-Hydroxymethyl-nicotinic acid methyl ester used for?
6-Hydroxymethyl-nicotinic acid methyl ester is a carboxylic acid that participates in diverse condensation and coupling reactions used primarily in the pharmaceutical and polymer industries. Key applications include amide bond formation via edc/hobt or hatu coupling in peptide synthesis and prodrug development to mask carboxylic acids and improve membrane permeability.
Where can I buy 6-Hydroxymethyl-nicotinic acid methyl ester in the USA?
ChemContract Research is a trusted USA-based supplier of 6-Hydroxymethyl-nicotinic acid methyl ester. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.
What purity levels are available for 6-Hydroxymethyl-nicotinic acid methyl ester?
ChemContract Research supplies 6-Hydroxymethyl-nicotinic acid methyl ester in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.
Can ChemContract synthesize 6-Hydroxymethyl-nicotinic acid methyl ester in custom quantities?
Yes. ChemContract Research offers custom synthesis services for 6-Hydroxymethyl-nicotinic acid methyl ester from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.
What is the stereochemical purity of 6-Hydroxymethyl-nicotinic acid methyl ester?
ChemContract Research supplies 6-Hydroxymethyl-nicotinic acid methyl ester with verified enantiomeric or diastereomeric purity as documented in our Certificate of Analysis (CoA). Chiral HPLC analysis is standard for stereodefined compounds. We can provide material with ≥98% ee/de for demanding applications. Contact us for specific optical purity requirements.
What coupling reagents work best with 6-Hydroxymethyl-nicotinic acid methyl ester?
For amide bond formation from the carboxylic acid in 6-Hydroxymethyl-nicotinic acid methyl ester, HATU/DIPEA is recommended for peptide coupling (high yield, low epimerization). EDC/HOBt is a cost-effective alternative for non-peptide amides. T3P (propylphosphonic acid anhydride) offers excellent atom economy with easy workup. For ester formation, DCC/DMAP (Steglich conditions) or Mitsunobu conditions are standard.
How should I store 6-Hydroxymethyl-nicotinic acid methyl ester?
Store at room temperature in a tightly sealed container. Protect from moisture and strong bases. Store at room temperature in a tightly sealed container away from heat and open flame. Store under recommended conditions. Some chiral compounds may racemize at elevated temperatures or in the presence of base. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.
What is the CAS number of 6-Hydroxymethyl-nicotinic acid methyl ester?
The CAS Registry Number for 6-Hydroxymethyl-nicotinic acid methyl ester is 56026-36-9. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.
