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5-Bromo Pyridine-3-Carboxylic Acid

CAS 20826-04-4 · Brominated Compound · 3 functional traits · cGMP compliant · Ships from USA in 2-3 days

Brominated Compound

5-Bromo Pyridine-3-Carboxylic Acid

Heterocycles PharmaceuticalFine ChemicalAgrochemicalResearchMedicinal ChemistryCatalysis
CAS Number 20826-04-4
Category Brominated Compound · Heterocyclic Compound
Origin USA
Compliance cGMP

Questions? Contact our chemistry team:

chemistry@chem-contract.com | +1 (714) 732-8549
In stock — typically ships within 2-3 business days

About 5-Bromo Pyridine-3-Carboxylic Acid

5-Bromo Pyridine-3-Carboxylic Acid (CAS Number: 20826-04-4) is a bromo-substituted intermediate prized for its reactivity in metal-catalyzed coupling featuring a Pyridine ring. ChemContract Research supplies this moderate-complexity compound in high purity from our Huntington Beach, California facility, ensuring consistent quality and reliable domestic delivery throughout the United States.

Aryl and alkyl bromides occupy a "Goldilocks zone" in cross-coupling — more reactive than chlorides yet more stable than iodides — making them the most commonly used coupling partners in process chemistry. Heterocyclic rings appear in approximately 85% of all biologically active compounds. The nitrogen, oxygen, or sulfur heteroatom modulates electron density, hydrogen bonding, and aqueous solubility. Carboxylic acids are among the most synthetically versatile functional groups — they can be converted to amides, esters, acid chlorides, anhydrides, alcohols, and aldehydes in a single step.

Primary applications include grignard reagent preparation via magnesium insertion into c–br bond and core scaffold in kinase inhibitor design for oncology therapeutics. This compound serves researchers and manufacturers across the pharmaceutical, fine chemical, agrochemical sectors. Whether you require 5-Bromo Pyridine-3-Carboxylic Acid for early-stage research, process development, or commercial-scale production, ChemContract Research offers flexible ordering from milligram to multi-kilogram quantities with custom synthesis options and full batch documentation including Certificates of Analysis (CoA) and Safety Data Sheets.

Ring Systems: Pyridine
Functional Groups: Carboxylic acid (–COOH)Bromine (C–Br)

Brominated Compound Applications & Target Industries

How 5-Bromo Pyridine-3-Carboxylic Acid is used across pharmaceutical and fine chemical sectors

01

Grignard reagent preparation via magnesium insertion into C–Br bond

02

Core scaffold in kinase inhibitor design for oncology therapeutics

03

Amide bond formation via EDC/HOBt or HATU coupling in peptide synthesis

04

Palladium-catalyzed Suzuki, Heck, and Negishi cross-coupling

05

GPCR modulator development for CNS and cardiovascular indications

06

Salt formation with amines to improve drug crystallinity and stability

Target Industries: PharmaceuticalFine ChemicalAgrochemicalResearchMedicinal ChemistryCatalysis

5-Bromo Pyridine-3-Carboxylic Acid Specifications

Detailed specifications for this brominated compound, including purity, molecular weight, and analytical data are available upon request. Every batch from ChemContract Research includes:

  • Certificate of Analysis (CoA) with purity verification
  • HPLC, NMR, and/or mass spectrometry characterization data
  • Material Safety Data Sheet (MSDS/SDS)
  • Batch-specific documentation and lot traceability
  • Custom analytical testing available on request
Request Full Specifications

Quick Reference

Compound Name 5-Bromo Pyridine-3-Carboxylic Acid
Type Brominated Compound
Category Brominated Compound · Heterocyclic Compound
Purity ≥95% (custom grades available)
Complexity Moderate (2 functional groups, 1 ring)
Compliance cGMP
Packaging mg to kg scale

Storage & Handling for Brominated Compounds

Handling Guidelines

Some brominated compounds may be lachrymatory or skin irritants. Handle in a fume hood with appropriate PPE. Handle with standard laboratory precautions. Some heterocycles may be hygroscopic or irritating. Use adequate ventilation. Acids may be corrosive or irritating. Handle with chemical-resistant gloves and eye protection. Use a fume hood for volatile acids.

Storage Conditions

Store at room temperature in a tightly sealed, light-resistant container. Some bromo compounds require refrigeration. Store at recommended temperature in a tightly sealed container. Some heterocyclic compounds are light-sensitive. Store at room temperature in a tightly sealed container. Protect from moisture and strong bases.

Why Buy 5-Bromo Pyridine-3-Carboxylic Acid From ChemContract?

Quality Assured

Every batch of 5-Bromo Pyridine-3-Carboxylic Acid is produced under cGMP conditions with full CoA documentation, HPLC purity verification, and lot traceability.

Fast USA Shipping

Ship from our Huntington Beach, CA facility with 2-3 business day domestic delivery. No import delays, no customs fees, no tariff surprises.

Custom Synthesis

Need a specific grade, quantity, or derivative of 5-Bromo Pyridine-3-Carboxylic Acid? Our team of PhD chemists can develop custom synthesis solutions for your exact requirements.

Frequently Asked

Common questions about 5-Bromo Pyridine-3-Carboxylic Acid

What is 5-Bromo Pyridine-3-Carboxylic Acid used for? +

5-Bromo Pyridine-3-Carboxylic Acid is a bromo-substituted intermediate prized for its reactivity in metal-catalyzed coupling used primarily in the pharmaceutical and fine chemical industries. Key applications include grignard reagent preparation via magnesium insertion into c–br bond and core scaffold in kinase inhibitor design for oncology therapeutics.

Where can I buy 5-Bromo Pyridine-3-Carboxylic Acid in the USA? +

ChemContract Research is a trusted USA-based supplier of 5-Bromo Pyridine-3-Carboxylic Acid. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.

What purity levels are available for 5-Bromo Pyridine-3-Carboxylic Acid? +

ChemContract Research supplies 5-Bromo Pyridine-3-Carboxylic Acid in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.

Can ChemContract synthesize 5-Bromo Pyridine-3-Carboxylic Acid in custom quantities? +

Yes. ChemContract Research offers custom synthesis services for 5-Bromo Pyridine-3-Carboxylic Acid from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.

What drug discovery applications use 5-Bromo Pyridine-3-Carboxylic Acid? +

The Pyridine ring system(s) in 5-Bromo Pyridine-3-Carboxylic Acid is a privileged structure in medicinal chemistry, appearing in numerous FDA-approved drugs. This scaffold is commonly used in kinase inhibitor design, GPCR modulator development, and lead optimization programs. ChemContract supplies this building block for early-stage discovery through process-scale manufacturing.

What coupling reactions can I run with 5-Bromo Pyridine-3-Carboxylic Acid? +

As a brominated compound, 5-Bromo Pyridine-3-Carboxylic Acid is an excellent substrate for palladium-catalyzed cross-coupling reactions including Suzuki, Heck, Negishi, Sonogashira, and Buchwald–Hartwig amination. It can also be used for Grignard reagent preparation, metal–halogen exchange with organolithium reagents, and nucleophilic substitution reactions.

How should I store 5-Bromo Pyridine-3-Carboxylic Acid? +

Store at room temperature in a tightly sealed, light-resistant container. Some bromo compounds require refrigeration. Store at recommended temperature in a tightly sealed container. Some heterocyclic compounds are light-sensitive. Store at room temperature in a tightly sealed container. Protect from moisture and strong bases. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.

What is the CAS number of 5-Bromo Pyridine-3-Carboxylic Acid? +

The CAS Registry Number for 5-Bromo Pyridine-3-Carboxylic Acid is 20826-04-4. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.

Chemical analysis laboratory with HPLC instruments for purity and impurity testing Custom chemical synthesis reaction setup for pharmaceutical intermediate production

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