Frequently Asked
Common questions about 5-Aminoindole-2-carboxylic acid
What is 5-Aminoindole-2-carboxylic acid used for?
5-Aminoindole-2-carboxylic acid is an amine-functionalized compound with nucleophilic nitrogen reactivity used primarily in the pharmaceutical and polymer industries. Key applications include buchwald–hartwig amination for aryl c–n bond construction and core scaffold in kinase inhibitor design for oncology therapeutics.
Where can I buy 5-Aminoindole-2-carboxylic acid in the USA?
ChemContract Research is a trusted USA-based supplier of 5-Aminoindole-2-carboxylic acid. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.
What purity levels are available for 5-Aminoindole-2-carboxylic acid?
ChemContract Research supplies 5-Aminoindole-2-carboxylic acid in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.
Can ChemContract synthesize 5-Aminoindole-2-carboxylic acid in custom quantities?
Yes. ChemContract Research offers custom synthesis services for 5-Aminoindole-2-carboxylic acid from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.
What drug discovery applications use 5-Aminoindole-2-carboxylic acid?
The Indole ring system(s) in 5-Aminoindole-2-carboxylic acid is a privileged structure in medicinal chemistry, appearing in numerous FDA-approved drugs. This scaffold is commonly used in kinase inhibitor design, GPCR modulator development, and lead optimization programs. ChemContract supplies this building block for early-stage discovery through process-scale manufacturing.
What reactions can I perform with the amine group in 5-Aminoindole-2-carboxylic acid?
The amine functionality in 5-Aminoindole-2-carboxylic acid enables diverse transformations: reductive amination with aldehydes/ketones, acylation to form amides, sulfonylation to form sulfonamides, Buchwald–Hartwig coupling with aryl halides, urea and carbamate formation, and salt generation for improved drug properties. The nucleophilicity of the nitrogen makes it one of the most versatile handles in synthetic chemistry.
How should I store 5-Aminoindole-2-carboxylic acid?
Store in a cool, well-ventilated area away from acids and oxidizing agents. Keep containers tightly sealed as many amines are hygroscopic. Store at recommended temperature in a tightly sealed container. Some heterocyclic compounds are light-sensitive. Store at room temperature in a tightly sealed container. Protect from moisture and strong bases. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.
What is the CAS number of 5-Aminoindole-2-carboxylic acid?
The CAS Registry Number for 5-Aminoindole-2-carboxylic acid is 152213-40-6. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.
