CAS 18880-00-7 · Brominated Compound · cGMP compliant · Ships from USA in 2-3 days
4-Tert-Butylbenzyl bromide (CAS Number: 18880-00-7) is a bromo-substituted intermediate prized for its reactivity in metal-catalyzed coupling. ChemContract Research supplies this simple-complexity compound in high purity from our Huntington Beach, California facility, ensuring consistent quality and reliable domestic delivery throughout the United States.
Aryl and alkyl bromides occupy a "Goldilocks zone" in cross-coupling — more reactive than chlorides yet more stable than iodides — making them the most commonly used coupling partners in process chemistry.
Primary applications include grignard reagent preparation via magnesium insertion into c–br bond. This compound serves researchers and manufacturers across the pharmaceutical, fine chemical, agrochemical sectors. Whether you require 4-Tert-Butylbenzyl bromide for early-stage research, process development, or commercial-scale production, ChemContract Research offers flexible ordering from milligram to multi-kilogram quantities with custom synthesis options and full batch documentation including Certificates of Analysis (CoA) and Safety Data Sheets.
How 4-Tert-Butylbenzyl bromide is used across pharmaceutical and fine chemical sectors
Grignard reagent preparation via magnesium insertion into C–Br bond
Palladium-catalyzed Suzuki, Heck, and Negishi cross-coupling
Nucleophilic substitution (SN2) for C–N, C–O, and C–S bond formation
Radical reactions including atom-transfer radical cyclization (ATRC)
Detailed specifications for this brominated compound, including purity, molecular weight, and analytical data are available upon request. Every batch from ChemContract Research includes:
Some brominated compounds may be lachrymatory or skin irritants. Handle in a fume hood with appropriate PPE.
Store at room temperature in a tightly sealed, light-resistant container. Some bromo compounds require refrigeration.
Aryl and alkyl bromides like 4-Tert-Butylbenzyl bromide are optimized for cross-coupling. We verify halide integrity and provide Pd-catalyst compatibility data on request.
Every batch of 4-Tert-Butylbenzyl bromide is produced under cGMP conditions with full CoA documentation, HPLC purity verification, and lot traceability.
Ship from our Huntington Beach, CA facility with 2-3 business day domestic delivery. No import delays, no customs fees, no tariff surprises.
Need a specific grade, quantity, or derivative of 4-Tert-Butylbenzyl bromide? Our team of PhD chemists can develop custom synthesis solutions for your exact requirements.
Common questions about 4-Tert-Butylbenzyl bromide
4-Tert-Butylbenzyl bromide is a bromo-substituted intermediate prized for its reactivity in metal-catalyzed coupling used primarily in the pharmaceutical and fine chemical industries. Key applications include grignard reagent preparation via magnesium insertion into c–br bond and palladium-catalyzed suzuki, heck, and negishi cross-coupling.
ChemContract Research is a trusted USA-based supplier of 4-Tert-Butylbenzyl bromide. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.
ChemContract Research supplies 4-Tert-Butylbenzyl bromide in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.
Yes. ChemContract Research offers custom synthesis services for 4-Tert-Butylbenzyl bromide from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.
As a brominated compound, 4-Tert-Butylbenzyl bromide is an excellent substrate for palladium-catalyzed cross-coupling reactions including Suzuki, Heck, Negishi, Sonogashira, and Buchwald–Hartwig amination. It can also be used for Grignard reagent preparation, metal–halogen exchange with organolithium reagents, and nucleophilic substitution reactions.
Store at room temperature in a tightly sealed, light-resistant container. Some bromo compounds require refrigeration. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.
The CAS Registry Number for 4-Tert-Butylbenzyl bromide is 18880-00-7. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.
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