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4-Tert-Butylbenzyl bromide

CAS 18880-00-7 · Brominated Compound · cGMP compliant · Ships from USA in 2-3 days

Brominated Compound

4-Tert-Butylbenzyl bromide

Halogenated PharmaceuticalFine ChemicalAgrochemicalResearch
CAS Number 18880-00-7
Category Brominated Compound
Origin USA
Compliance cGMP

Questions? Contact our chemistry team:

chemistry@chem-contract.com | +1 (714) 732-8549
In stock — typically ships within 2-3 business days

About 4-Tert-Butylbenzyl bromide

4-Tert-Butylbenzyl bromide (CAS Number: 18880-00-7) is a bromo-substituted intermediate prized for its reactivity in metal-catalyzed coupling. ChemContract Research supplies this simple-complexity compound in high purity from our Huntington Beach, California facility, ensuring consistent quality and reliable domestic delivery throughout the United States.

Aryl and alkyl bromides occupy a "Goldilocks zone" in cross-coupling — more reactive than chlorides yet more stable than iodides — making them the most commonly used coupling partners in process chemistry.

Primary applications include grignard reagent preparation via magnesium insertion into c–br bond. This compound serves researchers and manufacturers across the pharmaceutical, fine chemical, agrochemical sectors. Whether you require 4-Tert-Butylbenzyl bromide for early-stage research, process development, or commercial-scale production, ChemContract Research offers flexible ordering from milligram to multi-kilogram quantities with custom synthesis options and full batch documentation including Certificates of Analysis (CoA) and Safety Data Sheets.

Functional Groups: Bromine (C–Br)

Brominated Compound Applications & Target Industries

How 4-Tert-Butylbenzyl bromide is used across pharmaceutical and fine chemical sectors

01

Grignard reagent preparation via magnesium insertion into C–Br bond

02

Palladium-catalyzed Suzuki, Heck, and Negishi cross-coupling

03

Nucleophilic substitution (SN2) for C–N, C–O, and C–S bond formation

04

Radical reactions including atom-transfer radical cyclization (ATRC)

Target Industries: PharmaceuticalFine ChemicalAgrochemicalResearch

4-Tert-Butylbenzyl bromide Specifications

Detailed specifications for this brominated compound, including purity, molecular weight, and analytical data are available upon request. Every batch from ChemContract Research includes:

  • Certificate of Analysis (CoA) with purity verification
  • HPLC, NMR, and/or mass spectrometry characterization data
  • Material Safety Data Sheet (MSDS/SDS)
  • Batch-specific documentation and lot traceability
  • Custom analytical testing available on request
Request Full Specifications

Quick Reference

Compound Name 4-Tert-Butylbenzyl bromide
Type Brominated Compound
Category Brominated Compound
Purity ≥95% (custom grades available)
Complexity Simple (1 functional groups, 0 rings)
Compliance cGMP
Packaging mg to kg scale

Storage & Handling for Brominated Compounds

Handling Guidelines

Some brominated compounds may be lachrymatory or skin irritants. Handle in a fume hood with appropriate PPE.

Storage Conditions

Store at room temperature in a tightly sealed, light-resistant container. Some bromo compounds require refrigeration.

Why Buy 4-Tert-Butylbenzyl bromide From ChemContract?

Quality Assured

Every batch of 4-Tert-Butylbenzyl bromide is produced under cGMP conditions with full CoA documentation, HPLC purity verification, and lot traceability.

Fast USA Shipping

Ship from our Huntington Beach, CA facility with 2-3 business day domestic delivery. No import delays, no customs fees, no tariff surprises.

Custom Synthesis

Need a specific grade, quantity, or derivative of 4-Tert-Butylbenzyl bromide? Our team of PhD chemists can develop custom synthesis solutions for your exact requirements.

Frequently Asked

Common questions about 4-Tert-Butylbenzyl bromide

What is 4-Tert-Butylbenzyl bromide used for? +

4-Tert-Butylbenzyl bromide is a bromo-substituted intermediate prized for its reactivity in metal-catalyzed coupling used primarily in the pharmaceutical and fine chemical industries. Key applications include grignard reagent preparation via magnesium insertion into c–br bond and palladium-catalyzed suzuki, heck, and negishi cross-coupling.

Where can I buy 4-Tert-Butylbenzyl bromide in the USA? +

ChemContract Research is a trusted USA-based supplier of 4-Tert-Butylbenzyl bromide. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.

What purity levels are available for 4-Tert-Butylbenzyl bromide? +

ChemContract Research supplies 4-Tert-Butylbenzyl bromide in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.

Can ChemContract synthesize 4-Tert-Butylbenzyl bromide in custom quantities? +

Yes. ChemContract Research offers custom synthesis services for 4-Tert-Butylbenzyl bromide from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.

What coupling reactions can I run with 4-Tert-Butylbenzyl bromide? +

As a brominated compound, 4-Tert-Butylbenzyl bromide is an excellent substrate for palladium-catalyzed cross-coupling reactions including Suzuki, Heck, Negishi, Sonogashira, and Buchwald–Hartwig amination. It can also be used for Grignard reagent preparation, metal–halogen exchange with organolithium reagents, and nucleophilic substitution reactions.

How should I store 4-Tert-Butylbenzyl bromide? +

Store at room temperature in a tightly sealed, light-resistant container. Some bromo compounds require refrigeration. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.

What is the CAS number of 4-Tert-Butylbenzyl bromide? +

The CAS Registry Number for 4-Tert-Butylbenzyl bromide is 18880-00-7. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.

Chemical analysis laboratory with HPLC instruments for purity and impurity testing Custom chemical synthesis reaction setup for pharmaceutical intermediate production

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Get competitive pricing, custom quantities, and fast USA delivery. Our chemistry team is standing by to provide specifications, CoA documentation, and a tailored quote for your project.

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