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4-n-methylcarboxamidophenylboronic acid, pinacol ester

CAS 214360-57-3 · Boronic Acid / Boronate Ester · 2 functional traits · cGMP compliant · Ships from USA in 2-3 days

Boronic Acid / Boronate Ester

4-n-methylcarboxamidophenylboronic acid, pinacol ester

Boronic Acids PharmaceuticalMedicinal ChemistryDiagnosticsAgrochemicalPolymerFine Chemical
CAS Number 214360-57-3
Category Boronic Acid / Boronate Ester · Ester
Origin USA
Compliance cGMP

Questions? Contact our chemistry team:

chemistry@chem-contract.com | +1 (714) 732-8549
In stock — typically ships within 2-3 business days

About 4-n-methylcarboxamidophenylboronic acid, pinacol ester

4-n-methylcarboxamidophenylboronic acid, pinacol ester (CAS Number: 214360-57-3) is a boronic acid derivative valued for its role in carbon–carbon bond-forming reactions featuring a Benzene ring. ChemContract Research supplies this moderate-complexity compound in high purity from our Huntington Beach, California facility, ensuring consistent quality and reliable domestic delivery throughout the United States.

The boron atom in this compound enables transmetalation with palladium catalysts, making it a cornerstone reagent for Suzuki coupling — one of the most widely used reactions in pharmaceutical process chemistry. Ester hydrolysis by cellular esterases is the most commonly exploited prodrug activation mechanism — enabling drugs that cannot cross biological membranes as free acids.

Primary applications include suzuki–miyaura cross-coupling for biaryl and heterobiaryl synthesis and prodrug development to mask carboxylic acids and improve membrane permeability. This compound serves researchers and manufacturers across the pharmaceutical, medicinal chemistry, diagnostics sectors. Whether you require 4-n-methylcarboxamidophenylboronic acid, pinacol ester for early-stage research, process development, or commercial-scale production, ChemContract Research offers flexible ordering from milligram to multi-kilogram quantities with custom synthesis options and full batch documentation including Certificates of Analysis (CoA) and Safety Data Sheets.

Ring Systems: Benzene
Functional Groups: Boronic acidCarboxylic acid (–COOH)Ester (–COOR)

Boronic Acid / Boronate Ester Applications & Target Industries

How 4-n-methylcarboxamidophenylboronic acid, pinacol ester is used across pharmaceutical and medicinal chemistry sectors

01

Suzuki–Miyaura cross-coupling for biaryl and heterobiaryl synthesis

02

Prodrug development to mask carboxylic acids and improve membrane permeability

03

Proteasome inhibitor design in oncology drug development

04

Protecting group for hydroxyl functionalities (acetate, benzoate)

05

Saccharide and diol sensor development for diagnostic applications

06

Ring-opening polymerization monomer for biodegradable polymers

Target Industries: PharmaceuticalMedicinal ChemistryDiagnosticsAgrochemicalPolymerFine Chemical

4-n-methylcarboxamidophenylboronic acid, pinacol ester Specifications

Detailed specifications for this boronic acid / boronate ester, including purity, molecular weight, and analytical data are available upon request. Every batch from ChemContract Research includes:

  • Certificate of Analysis (CoA) with purity verification
  • HPLC, NMR, and/or mass spectrometry characterization data
  • Material Safety Data Sheet (MSDS/SDS)
  • Batch-specific documentation and lot traceability
  • Custom analytical testing available on request
Request Full Specifications

Quick Reference

Compound Name 4-n-methylcarboxamidophenylboronic acid, pinacol ester
Type Boronic Acid / Boronate Ester
Category Boronic Acid / Boronate Ester · Ester
Purity ≥95% (custom grades available)
Complexity Moderate (3 functional groups, 1 ring)
Compliance cGMP
Packaging mg to kg scale

Storage & Handling for Boronic Acid / Boronate Esters

Handling Guidelines

Boronic acids are generally air-stable but some may be moisture-sensitive and undergo protodeboronation. Handle with gloves and safety glasses. Some esters are volatile and flammable. Handle in a well-ventilated area. Keep away from ignition sources.

Storage Conditions

Store in a tightly sealed container at room temperature under dry conditions. Protect from prolonged moisture exposure. Store at room temperature in a tightly sealed container away from heat and open flame.

Why Buy 4-n-methylcarboxamidophenylboronic acid, pinacol ester From ChemContract?

Quality Assured

Every batch of 4-n-methylcarboxamidophenylboronic acid, pinacol ester is produced under cGMP conditions with full CoA documentation, HPLC purity verification, and lot traceability.

Fast USA Shipping

Ship from our Huntington Beach, CA facility with 2-3 business day domestic delivery. No import delays, no customs fees, no tariff surprises.

Custom Synthesis

Need a specific grade, quantity, or derivative of 4-n-methylcarboxamidophenylboronic acid, pinacol ester? Our team of PhD chemists can develop custom synthesis solutions for your exact requirements.

Frequently Asked

Common questions about 4-n-methylcarboxamidophenylboronic acid, pinacol ester

What is 4-n-methylcarboxamidophenylboronic acid, pinacol ester used for? +

4-n-methylcarboxamidophenylboronic acid, pinacol ester is a boronic acid derivative valued for its role in carbon–carbon bond-forming reactions used primarily in the pharmaceutical and medicinal chemistry industries. Key applications include suzuki–miyaura cross-coupling for biaryl and heterobiaryl synthesis and prodrug development to mask carboxylic acids and improve membrane permeability.

Where can I buy 4-n-methylcarboxamidophenylboronic acid, pinacol ester in the USA? +

ChemContract Research is a trusted USA-based supplier of 4-n-methylcarboxamidophenylboronic acid, pinacol ester. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.

What purity levels are available for 4-n-methylcarboxamidophenylboronic acid, pinacol ester? +

ChemContract Research supplies 4-n-methylcarboxamidophenylboronic acid, pinacol ester in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.

Can ChemContract synthesize 4-n-methylcarboxamidophenylboronic acid, pinacol ester in custom quantities? +

Yes. ChemContract Research offers custom synthesis services for 4-n-methylcarboxamidophenylboronic acid, pinacol ester from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.

What cross-coupling reactions can I use 4-n-methylcarboxamidophenylboronic acid, pinacol ester in? +

4-n-methylcarboxamidophenylboronic acid, pinacol ester is primarily used in Suzuki–Miyaura cross-coupling reactions with aryl or vinyl halides under palladium catalysis. This reaction forms C–C bonds with excellent functional group tolerance and mild conditions. It can also be used in Chan–Lam coupling for C–N and C–O bond formation without transition metal catalysts under aerobic conditions.

How should I store 4-n-methylcarboxamidophenylboronic acid, pinacol ester? +

Store in a tightly sealed container at room temperature under dry conditions. Protect from prolonged moisture exposure. Store at room temperature in a tightly sealed container away from heat and open flame. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.

What is the CAS number of 4-n-methylcarboxamidophenylboronic acid, pinacol ester? +

The CAS Registry Number for 4-n-methylcarboxamidophenylboronic acid, pinacol ester is 214360-57-3. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.

Chemical analysis laboratory with HPLC instruments for purity and impurity testing Custom chemical synthesis reaction setup for pharmaceutical intermediate production

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