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4-Iodobenzyl alcohol

CAS 18282-51-4 · Iodinated Compound · 2 functional traits · cGMP compliant · Ships from USA in 2-3 days

Iodinated Compound

4-Iodobenzyl alcohol

Halogenated PharmaceuticalNuclear MedicineFine ChemicalResearchFormulation
CAS Number 18282-51-4
Category Iodinated Compound · Alcohol / Hydroxyl Compound
Origin USA
Compliance cGMP

Questions? Contact our chemistry team:

chemistry@chem-contract.com | +1 (714) 732-8549
In stock — typically ships within 2-3 business days

About 4-Iodobenzyl alcohol

4-Iodobenzyl alcohol (CAS Number: 18282-51-4) is an iodo-substituted compound offering high reactivity in metal-mediated transformations. ChemContract Research supplies this simple-complexity compound in high purity from our Huntington Beach, California facility, ensuring consistent quality and reliable domestic delivery throughout the United States.

The C–I bond is the weakest carbon–halogen bond, which translates to the highest reactivity in oxidative addition — making aryl iodides the first-choice substrate for challenging cross-coupling reactions. Hydroxyl groups are critical pharmacophores — they serve as hydrogen-bond donors and acceptors, influencing drug–target binding, aqueous solubility, and metabolic susceptibility.

Primary applications include sonogashira and heck coupling with the lowest activation barrier among aryl halides and mitsunobu reaction substrate for stereospecific inversion at chiral centers. This compound serves researchers and manufacturers across the pharmaceutical, nuclear medicine, fine chemical sectors. Whether you require 4-Iodobenzyl alcohol for early-stage research, process development, or commercial-scale production, ChemContract Research offers flexible ordering from milligram to multi-kilogram quantities with custom synthesis options and full batch documentation including Certificates of Analysis (CoA) and Safety Data Sheets.

Functional Groups: Hydroxyl (–OH)Iodine (C–I)

Iodinated Compound Applications & Target Industries

How 4-Iodobenzyl alcohol is used across pharmaceutical and nuclear medicine sectors

01

Sonogashira and Heck coupling with the lowest activation barrier among aryl halides

02

Mitsunobu reaction substrate for stereospecific inversion at chiral centers

03

Radioiodination precursor for SPECT and PET diagnostic imaging

04

Oxidation to aldehydes (Swern, Dess–Martin) or ketones for downstream chemistry

05

Metal–halogen exchange with n-BuLi for directed metalation strategies

06

Ether formation via Williamson synthesis for drug analog SAR studies

Target Industries: PharmaceuticalNuclear MedicineFine ChemicalResearchFormulation

4-Iodobenzyl alcohol Specifications

Detailed specifications for this iodinated compound, including purity, molecular weight, and analytical data are available upon request. Every batch from ChemContract Research includes:

  • Certificate of Analysis (CoA) with purity verification
  • HPLC, NMR, and/or mass spectrometry characterization data
  • Material Safety Data Sheet (MSDS/SDS)
  • Batch-specific documentation and lot traceability
  • Custom analytical testing available on request
Request Full Specifications

Quick Reference

Compound Name 4-Iodobenzyl alcohol
Type Iodinated Compound
Category Iodinated Compound · Alcohol / Hydroxyl Compound
Purity ≥95% (custom grades available)
Complexity Simple (2 functional groups, 0 rings)
Compliance cGMP
Packaging mg to kg scale

Storage & Handling for Iodinated Compounds

Handling Guidelines

Iodo compounds may be light-sensitive and can stain skin. Handle in a fume hood and protect from light during use. Handle with standard precautions. Some alcohols are flammable. Use adequate ventilation and appropriate PPE.

Storage Conditions

Store refrigerated (2–8 °C) in a light-resistant, tightly sealed container under inert atmosphere to prevent degradation. Store at room temperature in a tightly sealed container away from heat sources and oxidizers.

Why Buy 4-Iodobenzyl alcohol From ChemContract?

Quality Assured

Every batch of 4-Iodobenzyl alcohol is produced under cGMP conditions with full CoA documentation, HPLC purity verification, and lot traceability.

Fast USA Shipping

Ship from our Huntington Beach, CA facility with 2-3 business day domestic delivery. No import delays, no customs fees, no tariff surprises.

Custom Synthesis

Need a specific grade, quantity, or derivative of 4-Iodobenzyl alcohol? Our team of PhD chemists can develop custom synthesis solutions for your exact requirements.

Frequently Asked

Common questions about 4-Iodobenzyl alcohol

What is 4-Iodobenzyl alcohol used for? +

4-Iodobenzyl alcohol is an iodo-substituted compound offering high reactivity in metal-mediated transformations used primarily in the pharmaceutical and nuclear medicine industries. Key applications include sonogashira and heck coupling with the lowest activation barrier among aryl halides and mitsunobu reaction substrate for stereospecific inversion at chiral centers.

Where can I buy 4-Iodobenzyl alcohol in the USA? +

ChemContract Research is a trusted USA-based supplier of 4-Iodobenzyl alcohol. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.

What purity levels are available for 4-Iodobenzyl alcohol? +

ChemContract Research supplies 4-Iodobenzyl alcohol in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.

Can ChemContract synthesize 4-Iodobenzyl alcohol in custom quantities? +

Yes. ChemContract Research offers custom synthesis services for 4-Iodobenzyl alcohol from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.

What coupling reactions can I run with 4-Iodobenzyl alcohol? +

As a iodinated compound, 4-Iodobenzyl alcohol is an excellent substrate for palladium-catalyzed cross-coupling reactions including Suzuki, Heck, Negishi, Sonogashira, and Buchwald–Hartwig amination. It can also be used for Grignard reagent preparation, metal–halogen exchange with organolithium reagents, and nucleophilic substitution reactions.

How should I store 4-Iodobenzyl alcohol? +

Store refrigerated (2–8 °C) in a light-resistant, tightly sealed container under inert atmosphere to prevent degradation. Store at room temperature in a tightly sealed container away from heat sources and oxidizers. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.

What is the CAS number of 4-Iodobenzyl alcohol? +

The CAS Registry Number for 4-Iodobenzyl alcohol is 18282-51-4. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.

Chemical analysis laboratory with HPLC instruments for purity and impurity testing Custom chemical synthesis reaction setup for pharmaceutical intermediate production

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Get competitive pricing, custom quantities, and fast USA delivery. Our chemistry team is standing by to provide specifications, CoA documentation, and a tailored quote for your project.

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