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4-Bromo-7-azaindole

CAS 348640-06-2 · Brominated Compound · 2 functional traits · cGMP compliant · Ships from USA in 2-3 days

Brominated Compound

4-Bromo-7-azaindole

Heterocycles PharmaceuticalFine ChemicalAgrochemicalResearchMedicinal ChemistryCatalysis
CAS Number 348640-06-2
Category Brominated Compound · Heterocyclic Compound
Origin USA
Compliance cGMP

Questions? Contact our chemistry team:

chemistry@chem-contract.com | +1 (714) 732-8549
In stock — typically ships within 2-3 business days

About 4-Bromo-7-azaindole

4-Bromo-7-azaindole (CAS Number: 348640-06-2) is a bromo-substituted intermediate prized for its reactivity in metal-catalyzed coupling featuring a Indole ring. ChemContract Research supplies this simple-complexity compound in high purity from our Huntington Beach, California facility, ensuring consistent quality and reliable domestic delivery throughout the United States.

Aryl and alkyl bromides occupy a "Goldilocks zone" in cross-coupling — more reactive than chlorides yet more stable than iodides — making them the most commonly used coupling partners in process chemistry. Heterocyclic rings appear in approximately 85% of all biologically active compounds. The nitrogen, oxygen, or sulfur heteroatom modulates electron density, hydrogen bonding, and aqueous solubility.

Primary applications include grignard reagent preparation via magnesium insertion into c–br bond and core scaffold in kinase inhibitor design for oncology therapeutics. This compound serves researchers and manufacturers across the pharmaceutical, fine chemical, agrochemical sectors. Whether you require 4-Bromo-7-azaindole for early-stage research, process development, or commercial-scale production, ChemContract Research offers flexible ordering from milligram to multi-kilogram quantities with custom synthesis options and full batch documentation including Certificates of Analysis (CoA) and Safety Data Sheets.

Ring Systems: Indole
Functional Groups: Bromine (C–Br)

Brominated Compound Applications & Target Industries

How 4-Bromo-7-azaindole is used across pharmaceutical and fine chemical sectors

01

Grignard reagent preparation via magnesium insertion into C–Br bond

02

Core scaffold in kinase inhibitor design for oncology therapeutics

03

Palladium-catalyzed Suzuki, Heck, and Negishi cross-coupling

04

GPCR modulator development for CNS and cardiovascular indications

05

Nucleophilic substitution (SN2) for C–N, C–O, and C–S bond formation

06

Herbicide and fungicide scaffolds in modern crop protection

Target Industries: PharmaceuticalFine ChemicalAgrochemicalResearchMedicinal ChemistryCatalysis

4-Bromo-7-azaindole Specifications

Detailed specifications for this brominated compound, including purity, molecular weight, and analytical data are available upon request. Every batch from ChemContract Research includes:

  • Certificate of Analysis (CoA) with purity verification
  • HPLC, NMR, and/or mass spectrometry characterization data
  • Material Safety Data Sheet (MSDS/SDS)
  • Batch-specific documentation and lot traceability
  • Custom analytical testing available on request
Request Full Specifications

Quick Reference

Compound Name 4-Bromo-7-azaindole
Type Brominated Compound
Category Brominated Compound · Heterocyclic Compound
Purity ≥95% (custom grades available)
Complexity Simple (1 functional groups, 1 ring)
Compliance cGMP
Packaging mg to kg scale

Storage & Handling for Brominated Compounds

Handling Guidelines

Some brominated compounds may be lachrymatory or skin irritants. Handle in a fume hood with appropriate PPE. Handle with standard laboratory precautions. Some heterocycles may be hygroscopic or irritating. Use adequate ventilation.

Storage Conditions

Store at room temperature in a tightly sealed, light-resistant container. Some bromo compounds require refrigeration. Store at recommended temperature in a tightly sealed container. Some heterocyclic compounds are light-sensitive.

Why Buy 4-Bromo-7-azaindole From ChemContract?

Quality Assured

Every batch of 4-Bromo-7-azaindole is produced under cGMP conditions with full CoA documentation, HPLC purity verification, and lot traceability.

Fast USA Shipping

Ship from our Huntington Beach, CA facility with 2-3 business day domestic delivery. No import delays, no customs fees, no tariff surprises.

Custom Synthesis

Need a specific grade, quantity, or derivative of 4-Bromo-7-azaindole? Our team of PhD chemists can develop custom synthesis solutions for your exact requirements.

Frequently Asked

Common questions about 4-Bromo-7-azaindole

What is 4-Bromo-7-azaindole used for? +

4-Bromo-7-azaindole is a bromo-substituted intermediate prized for its reactivity in metal-catalyzed coupling used primarily in the pharmaceutical and fine chemical industries. Key applications include grignard reagent preparation via magnesium insertion into c–br bond and core scaffold in kinase inhibitor design for oncology therapeutics.

Where can I buy 4-Bromo-7-azaindole in the USA? +

ChemContract Research is a trusted USA-based supplier of 4-Bromo-7-azaindole. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.

What purity levels are available for 4-Bromo-7-azaindole? +

ChemContract Research supplies 4-Bromo-7-azaindole in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.

Can ChemContract synthesize 4-Bromo-7-azaindole in custom quantities? +

Yes. ChemContract Research offers custom synthesis services for 4-Bromo-7-azaindole from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.

What coupling reactions can I run with 4-Bromo-7-azaindole? +

As a brominated compound, 4-Bromo-7-azaindole is an excellent substrate for palladium-catalyzed cross-coupling reactions including Suzuki, Heck, Negishi, Sonogashira, and Buchwald–Hartwig amination. It can also be used for Grignard reagent preparation, metal–halogen exchange with organolithium reagents, and nucleophilic substitution reactions.

What drug discovery applications use 4-Bromo-7-azaindole? +

The Indole ring system(s) in 4-Bromo-7-azaindole is a privileged structure in medicinal chemistry, appearing in numerous FDA-approved drugs. This scaffold is commonly used in kinase inhibitor design, GPCR modulator development, and lead optimization programs. ChemContract supplies this building block for early-stage discovery through process-scale manufacturing.

How should I store 4-Bromo-7-azaindole? +

Store at room temperature in a tightly sealed, light-resistant container. Some bromo compounds require refrigeration. Store at recommended temperature in a tightly sealed container. Some heterocyclic compounds are light-sensitive. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.

What is the CAS number of 4-Bromo-7-azaindole? +

The CAS Registry Number for 4-Bromo-7-azaindole is 348640-06-2. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.

Chemical analysis laboratory with HPLC instruments for purity and impurity testing Custom chemical synthesis reaction setup for pharmaceutical intermediate production

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