Frequently Asked
Common questions about 4-Aminophenylboronic acid pinacol ester
What is 4-Aminophenylboronic acid pinacol ester used for?
4-Aminophenylboronic acid pinacol ester is a boronic acid derivative valued for its role in carbon–carbon bond-forming reactions used primarily in the pharmaceutical and medicinal chemistry industries. Key applications include suzuki–miyaura cross-coupling for biaryl and heterobiaryl synthesis and buchwald–hartwig amination for aryl c–n bond construction.
Where can I buy 4-Aminophenylboronic acid pinacol ester in the USA?
ChemContract Research is a trusted USA-based supplier of 4-Aminophenylboronic acid pinacol ester. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.
What purity levels are available for 4-Aminophenylboronic acid pinacol ester?
ChemContract Research supplies 4-Aminophenylboronic acid pinacol ester in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.
Can ChemContract synthesize 4-Aminophenylboronic acid pinacol ester in custom quantities?
Yes. ChemContract Research offers custom synthesis services for 4-Aminophenylboronic acid pinacol ester from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.
What cross-coupling reactions can I use 4-Aminophenylboronic acid pinacol ester in?
4-Aminophenylboronic acid pinacol ester is primarily used in Suzuki–Miyaura cross-coupling reactions with aryl or vinyl halides under palladium catalysis. This reaction forms C–C bonds with excellent functional group tolerance and mild conditions. It can also be used in Chan–Lam coupling for C–N and C–O bond formation without transition metal catalysts under aerobic conditions.
What reactions can I perform with the amine group in 4-Aminophenylboronic acid pinacol ester?
The amine functionality in 4-Aminophenylboronic acid pinacol ester enables diverse transformations: reductive amination with aldehydes/ketones, acylation to form amides, sulfonylation to form sulfonamides, Buchwald–Hartwig coupling with aryl halides, urea and carbamate formation, and salt generation for improved drug properties. The nucleophilicity of the nitrogen makes it one of the most versatile handles in synthetic chemistry.
How should I store 4-Aminophenylboronic acid pinacol ester?
Store in a tightly sealed container at room temperature under dry conditions. Protect from prolonged moisture exposure. Store in a cool, well-ventilated area away from acids and oxidizing agents. Keep containers tightly sealed as many amines are hygroscopic. Store at room temperature in a tightly sealed container away from heat and open flame. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.
What is the CAS number of 4-Aminophenylboronic acid pinacol ester?
The CAS Registry Number for 4-Aminophenylboronic acid pinacol ester is 214360-73-3. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.
