Frequently Asked
Common questions about 4-Amino-3-bromobenzoic Acid
What is 4-Amino-3-bromobenzoic Acid used for?
4-Amino-3-bromobenzoic Acid is an amine-functionalized compound with nucleophilic nitrogen reactivity used primarily in the pharmaceutical and polymer industries. Key applications include buchwald–hartwig amination for aryl c–n bond construction and grignard reagent preparation via magnesium insertion into c–br bond.
Where can I buy 4-Amino-3-bromobenzoic Acid in the USA?
ChemContract Research is a trusted USA-based supplier of 4-Amino-3-bromobenzoic Acid. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.
What purity levels are available for 4-Amino-3-bromobenzoic Acid?
ChemContract Research supplies 4-Amino-3-bromobenzoic Acid in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.
Can ChemContract synthesize 4-Amino-3-bromobenzoic Acid in custom quantities?
Yes. ChemContract Research offers custom synthesis services for 4-Amino-3-bromobenzoic Acid from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.
What coupling reactions can I run with 4-Amino-3-bromobenzoic Acid?
As a brominated compound, 4-Amino-3-bromobenzoic Acid is an excellent substrate for palladium-catalyzed cross-coupling reactions including Suzuki, Heck, Negishi, Sonogashira, and Buchwald–Hartwig amination. It can also be used for Grignard reagent preparation, metal–halogen exchange with organolithium reagents, and nucleophilic substitution reactions.
What reactions can I perform with the amine group in 4-Amino-3-bromobenzoic Acid?
The amine functionality in 4-Amino-3-bromobenzoic Acid enables diverse transformations: reductive amination with aldehydes/ketones, acylation to form amides, sulfonylation to form sulfonamides, Buchwald–Hartwig coupling with aryl halides, urea and carbamate formation, and salt generation for improved drug properties. The nucleophilicity of the nitrogen makes it one of the most versatile handles in synthetic chemistry.
How should I store 4-Amino-3-bromobenzoic Acid?
Store in a cool, well-ventilated area away from acids and oxidizing agents. Keep containers tightly sealed as many amines are hygroscopic. Store at room temperature in a tightly sealed, light-resistant container. Some bromo compounds require refrigeration. Store at room temperature in a tightly sealed container. Protect from moisture and strong bases. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.
