Frequently Asked
Common questions about 4-(4-Chlorophenyl)piperidine HCl
What is 4-(4-Chlorophenyl)piperidine HCl used for?
4-(4-Chlorophenyl)piperidine HCl is a chloro-substituted intermediate widely used in nucleophilic displacement reactions used primarily in the pharmaceutical and agrochemical industries. Key applications include nucleophilic aromatic substitution (snar) for ether and amine formation and cns drug scaffold (present in donepezil, methylphenidate, fentanyl class).
Where can I buy 4-(4-Chlorophenyl)piperidine HCl in the USA?
ChemContract Research is a trusted USA-based supplier of 4-(4-Chlorophenyl)piperidine HCl. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.
What purity levels are available for 4-(4-Chlorophenyl)piperidine HCl?
ChemContract Research supplies 4-(4-Chlorophenyl)piperidine HCl in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.
Can ChemContract synthesize 4-(4-Chlorophenyl)piperidine HCl in custom quantities?
Yes. ChemContract Research offers custom synthesis services for 4-(4-Chlorophenyl)piperidine HCl from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.
What drug discovery applications use 4-(4-Chlorophenyl)piperidine HCl?
The Piperidine ring system(s) in 4-(4-Chlorophenyl)piperidine HCl is a privileged structure in medicinal chemistry, appearing in numerous FDA-approved drugs. This scaffold is commonly used in kinase inhibitor design, GPCR modulator development, and lead optimization programs. ChemContract supplies this building block for early-stage discovery through process-scale manufacturing.
What coupling reactions can I run with 4-(4-Chlorophenyl)piperidine HCl?
As a chlorinated compound, 4-(4-Chlorophenyl)piperidine HCl is an excellent substrate for palladium-catalyzed cross-coupling reactions including Suzuki, Heck, Negishi, Sonogashira, and Buchwald–Hartwig amination. It can also be used for Grignard reagent preparation, metal–halogen exchange with organolithium reagents, and nucleophilic substitution reactions.
How should I store 4-(4-Chlorophenyl)piperidine HCl?
Store at recommended temperature in a well-sealed container. Protect from moisture and strong bases. Store at room temperature in a well-sealed container. Some N-unsubstituted piperidines are volatile. Store at room temperature in a tightly sealed container. Protect from humidity. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.
