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3-Nitro-4-methoxybenzyl sulfonyl acetic acid

CAS 592542-51-3 · Sulfur-Containing Compound · 2 functional traits · cGMP compliant · Ships from USA in 2-3 days

Sulfur-Containing Compound

3-Nitro-4-methoxybenzyl sulfonyl acetic acid

Sulfonyl PharmaceuticalMedicinal ChemistryAgrochemicalPolymerFine Chemical
CAS Number 592542-51-3
Category Sulfur-Containing Compound · Carboxylic Acid
Origin USA
Compliance cGMP

Questions? Contact our chemistry team:

chemistry@chem-contract.com | +1 (714) 732-8549
In stock — typically ships within 2-3 business days

About 3-Nitro-4-methoxybenzyl sulfonyl acetic acid

3-Nitro-4-methoxybenzyl sulfonyl acetic acid (CAS Number: 592542-51-3) is a sulfur-functionalized compound with diverse reactivity. ChemContract Research supplies this moderate-complexity compound in high purity from our Huntington Beach, California facility, ensuring consistent quality and reliable domestic delivery throughout the United States.

Sulfonamides are one of the oldest and most successful pharmacophores in medicinal chemistry — present in antibiotics, diuretics, COX-2 inhibitors, and HIV protease inhibitors. Carboxylic acids are among the most synthetically versatile functional groups — they can be converted to amides, esters, acid chlorides, anhydrides, alcohols, and aldehydes in a single step.

Primary applications include sulfonamide pharmacophore installation for antibiotic and diuretic development and amide bond formation via edc/hobt or hatu coupling in peptide synthesis. This compound serves researchers and manufacturers across the pharmaceutical, medicinal chemistry, agrochemical sectors. Whether you require 3-Nitro-4-methoxybenzyl sulfonyl acetic acid for early-stage research, process development, or commercial-scale production, ChemContract Research offers flexible ordering from milligram to multi-kilogram quantities with custom synthesis options and full batch documentation including Certificates of Analysis (CoA) and Safety Data Sheets.

Functional Groups: Carboxylic acid (–COOH)Nitro (–NO₂)Alkoxy (–OR)

Sulfur-Containing Compound Applications & Target Industries

How 3-Nitro-4-methoxybenzyl sulfonyl acetic acid is used across pharmaceutical and medicinal chemistry sectors

01

Sulfonamide pharmacophore installation for antibiotic and diuretic development

02

Amide bond formation via EDC/HOBt or HATU coupling in peptide synthesis

03

Tosyl and mesyl protecting groups for hydroxyl and amine functionalities

04

Salt formation with amines to improve drug crystallinity and stability

05

Triflate leaving group for palladium-catalyzed cross-coupling

06

Ester prodrug synthesis for enhanced oral bioavailability

Target Industries: PharmaceuticalMedicinal ChemistryAgrochemicalPolymerFine Chemical

3-Nitro-4-methoxybenzyl sulfonyl acetic acid Specifications

Detailed specifications for this sulfur-containing compound, including purity, molecular weight, and analytical data are available upon request. Every batch from ChemContract Research includes:

  • Certificate of Analysis (CoA) with purity verification
  • HPLC, NMR, and/or mass spectrometry characterization data
  • Material Safety Data Sheet (MSDS/SDS)
  • Batch-specific documentation and lot traceability
  • Custom analytical testing available on request
Request Full Specifications

Quick Reference

Compound Name 3-Nitro-4-methoxybenzyl sulfonyl acetic acid
Type Sulfur-Containing Compound
Category Sulfur-Containing Compound · Carboxylic Acid
Purity ≥95% (custom grades available)
Complexity Moderate (3 functional groups, 0 rings)
Compliance cGMP
Packaging mg to kg scale

Storage & Handling for Sulfur-Containing Compounds

Handling Guidelines

Some sulfur compounds have strong odors. Handle in a well-ventilated fume hood. Consult the SDS for compound-specific hazards. Acids may be corrosive or irritating. Handle with chemical-resistant gloves and eye protection. Use a fume hood for volatile acids.

Storage Conditions

Store in a cool, dry place in a tightly sealed container. Protect from moisture and light as specified. Store at room temperature in a tightly sealed container. Protect from moisture and strong bases.

Why Buy 3-Nitro-4-methoxybenzyl sulfonyl acetic acid From ChemContract?

Quality Assured

Every batch of 3-Nitro-4-methoxybenzyl sulfonyl acetic acid is produced under cGMP conditions with full CoA documentation, HPLC purity verification, and lot traceability.

Fast USA Shipping

Ship from our Huntington Beach, CA facility with 2-3 business day domestic delivery. No import delays, no customs fees, no tariff surprises.

Custom Synthesis

Need a specific grade, quantity, or derivative of 3-Nitro-4-methoxybenzyl sulfonyl acetic acid? Our team of PhD chemists can develop custom synthesis solutions for your exact requirements.

Frequently Asked

Common questions about 3-Nitro-4-methoxybenzyl sulfonyl acetic acid

What is 3-Nitro-4-methoxybenzyl sulfonyl acetic acid used for? +

3-Nitro-4-methoxybenzyl sulfonyl acetic acid is a sulfur-functionalized compound with diverse reactivity used primarily in the pharmaceutical and medicinal chemistry industries. Key applications include sulfonamide pharmacophore installation for antibiotic and diuretic development and amide bond formation via edc/hobt or hatu coupling in peptide synthesis.

Where can I buy 3-Nitro-4-methoxybenzyl sulfonyl acetic acid in the USA? +

ChemContract Research is a trusted USA-based supplier of 3-Nitro-4-methoxybenzyl sulfonyl acetic acid. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.

What purity levels are available for 3-Nitro-4-methoxybenzyl sulfonyl acetic acid? +

ChemContract Research supplies 3-Nitro-4-methoxybenzyl sulfonyl acetic acid in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.

Can ChemContract synthesize 3-Nitro-4-methoxybenzyl sulfonyl acetic acid in custom quantities? +

Yes. ChemContract Research offers custom synthesis services for 3-Nitro-4-methoxybenzyl sulfonyl acetic acid from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.

What coupling reagents work best with 3-Nitro-4-methoxybenzyl sulfonyl acetic acid? +

For amide bond formation from the carboxylic acid in 3-Nitro-4-methoxybenzyl sulfonyl acetic acid, HATU/DIPEA is recommended for peptide coupling (high yield, low epimerization). EDC/HOBt is a cost-effective alternative for non-peptide amides. T3P (propylphosphonic acid anhydride) offers excellent atom economy with easy workup. For ester formation, DCC/DMAP (Steglich conditions) or Mitsunobu conditions are standard.

How should I store 3-Nitro-4-methoxybenzyl sulfonyl acetic acid? +

Store in a cool, dry place in a tightly sealed container. Protect from moisture and light as specified. Store at room temperature in a tightly sealed container. Protect from moisture and strong bases. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.

What is the CAS number of 3-Nitro-4-methoxybenzyl sulfonyl acetic acid? +

The CAS Registry Number for 3-Nitro-4-methoxybenzyl sulfonyl acetic acid is 592542-51-3. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.

Chemical analysis laboratory with HPLC instruments for purity and impurity testing Custom chemical synthesis reaction setup for pharmaceutical intermediate production

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