CAS 913835-32-2 · Boronic Acid / Boronate Ester · 2 functional traits · cGMP compliant · Ships from USA in 2-3 days
3-Carboxy-4-chlorobenzeneboronic acid (CAS Number: 913835-32-2) is a boronic acid derivative valued for its role in carbon–carbon bond-forming reactions featuring a Benzene ring. ChemContract Research supplies this moderate-complexity compound in high purity from our Huntington Beach, California facility, ensuring consistent quality and reliable domestic delivery throughout the United States.
The boron atom in this compound enables transmetalation with palladium catalysts, making it a cornerstone reagent for Suzuki coupling — one of the most widely used reactions in pharmaceutical process chemistry. Chloro substituents serve a dual role in drug design — as synthetic handles for late-stage functionalization and as bioisosteres that modulate lipophilicity and binding affinity.
Primary applications include suzuki–miyaura cross-coupling for biaryl and heterobiaryl synthesis and nucleophilic aromatic substitution (snar) for ether and amine formation. This compound serves researchers and manufacturers across the pharmaceutical, medicinal chemistry, diagnostics sectors. Whether you require 3-Carboxy-4-chlorobenzeneboronic acid for early-stage research, process development, or commercial-scale production, ChemContract Research offers flexible ordering from milligram to multi-kilogram quantities with custom synthesis options and full batch documentation including Certificates of Analysis (CoA) and Safety Data Sheets.
How 3-Carboxy-4-chlorobenzeneboronic acid is used across pharmaceutical and medicinal chemistry sectors
Suzuki–Miyaura cross-coupling for biaryl and heterobiaryl synthesis
Nucleophilic aromatic substitution (SNAr) for ether and amine formation
Proteasome inhibitor design in oncology drug development
Grignard reagent precursor for C–C bond construction
Saccharide and diol sensor development for diagnostic applications
Acyl chloride reactivity for amide and ester formation
Detailed specifications for this boronic acid / boronate ester, including purity, molecular weight, and analytical data are available upon request. Every batch from ChemContract Research includes:
Boronic acids are generally air-stable but some may be moisture-sensitive and undergo protodeboronation. Handle with gloves and safety glasses. Some chlorinated compounds are volatile or irritating. Use a fume hood and appropriate PPE. Acid chlorides react vigorously with water.
Store in a tightly sealed container at room temperature under dry conditions. Protect from prolonged moisture exposure. Store at recommended temperature in a well-sealed container. Protect from moisture and strong bases.
Our chemists optimize Suzuki and Chan–Lam coupling conditions for boronic acid building blocks like 3-Carboxy-4-chlorobenzeneboronic acid. Get application support alongside your order.
Every batch of 3-Carboxy-4-chlorobenzeneboronic acid is produced under cGMP conditions with full CoA documentation, HPLC purity verification, and lot traceability.
Ship from our Huntington Beach, CA facility with 2-3 business day domestic delivery. No import delays, no customs fees, no tariff surprises.
Need a specific grade, quantity, or derivative of 3-Carboxy-4-chlorobenzeneboronic acid? Our team of PhD chemists can develop custom synthesis solutions for your exact requirements.
Common questions about 3-Carboxy-4-chlorobenzeneboronic acid
3-Carboxy-4-chlorobenzeneboronic acid is a boronic acid derivative valued for its role in carbon–carbon bond-forming reactions used primarily in the pharmaceutical and medicinal chemistry industries. Key applications include suzuki–miyaura cross-coupling for biaryl and heterobiaryl synthesis and nucleophilic aromatic substitution (snar) for ether and amine formation.
ChemContract Research is a trusted USA-based supplier of 3-Carboxy-4-chlorobenzeneboronic acid. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.
ChemContract Research supplies 3-Carboxy-4-chlorobenzeneboronic acid in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.
Yes. ChemContract Research offers custom synthesis services for 3-Carboxy-4-chlorobenzeneboronic acid from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.
3-Carboxy-4-chlorobenzeneboronic acid is primarily used in Suzuki–Miyaura cross-coupling reactions with aryl or vinyl halides under palladium catalysis. This reaction forms C–C bonds with excellent functional group tolerance and mild conditions. It can also be used in Chan–Lam coupling for C–N and C–O bond formation without transition metal catalysts under aerobic conditions.
As a chlorinated compound, 3-Carboxy-4-chlorobenzeneboronic acid is an excellent substrate for palladium-catalyzed cross-coupling reactions including Suzuki, Heck, Negishi, Sonogashira, and Buchwald–Hartwig amination. It can also be used for Grignard reagent preparation, metal–halogen exchange with organolithium reagents, and nucleophilic substitution reactions.
Store in a tightly sealed container at room temperature under dry conditions. Protect from prolonged moisture exposure. Store at recommended temperature in a well-sealed container. Protect from moisture and strong bases. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.
The CAS Registry Number for 3-Carboxy-4-chlorobenzeneboronic acid is 913835-32-2. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.
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