CAS 102776-55-6 · Brominated Compound · 2 functional traits · cGMP compliant · Ships from USA in 2-3 days
3-bromopiperidine HBr >95% (NMR) (CAS Number: 102776-55-6) is a bromo-substituted intermediate prized for its reactivity in metal-catalyzed coupling featuring a Piperidine ring. ChemContract Research supplies this simple-complexity compound in high purity from our Huntington Beach, California facility, ensuring consistent quality and reliable domestic delivery throughout the United States.
Aryl and alkyl bromides occupy a "Goldilocks zone" in cross-coupling — more reactive than chlorides yet more stable than iodides — making them the most commonly used coupling partners in process chemistry. The piperidine ring is the most common nitrogen heterocycle in FDA-approved drugs, appearing in over 70 marketed pharmaceuticals across CNS, cardiovascular, and oncology indications.
Primary applications include grignard reagent preparation via magnesium insertion into c–br bond and cns drug scaffold (present in donepezil, methylphenidate, fentanyl class). This compound serves researchers and manufacturers across the pharmaceutical, fine chemical, agrochemical sectors. Whether you require 3-bromopiperidine HBr >95% (NMR) for early-stage research, process development, or commercial-scale production, ChemContract Research offers flexible ordering from milligram to multi-kilogram quantities with custom synthesis options and full batch documentation including Certificates of Analysis (CoA) and Safety Data Sheets.
How 3-bromopiperidine HBr >95% (NMR) is used across pharmaceutical and fine chemical sectors
Grignard reagent preparation via magnesium insertion into C–Br bond
CNS drug scaffold (present in donepezil, methylphenidate, fentanyl class)
Palladium-catalyzed Suzuki, Heck, and Negishi cross-coupling
Conformationally-restricted amine for receptor binding optimization
Nucleophilic substitution (SN2) for C–N, C–O, and C–S bond formation
Spirocyclic and fused ring system construction for 3D drug design
Detailed specifications for this brominated compound, including purity, molecular weight, and analytical data are available upon request. Every batch from ChemContract Research includes:
Some brominated compounds may be lachrymatory or skin irritants. Handle in a fume hood with appropriate PPE. Handle with standard precautions. Piperidine and some derivatives have strong amine odors. Use a fume hood.
Store at room temperature in a tightly sealed, light-resistant container. Some bromo compounds require refrigeration. Store at room temperature in a well-sealed container. Some N-unsubstituted piperidines are volatile.
Aryl and alkyl bromides like 3-bromopiperidine HBr >95% (NMR) are optimized for cross-coupling. We verify halide integrity and provide Pd-catalyst compatibility data on request.
Every batch of 3-bromopiperidine HBr >95% (NMR) is produced under cGMP conditions with full CoA documentation, HPLC purity verification, and lot traceability.
Ship from our Huntington Beach, CA facility with 2-3 business day domestic delivery. No import delays, no customs fees, no tariff surprises.
Need a specific grade, quantity, or derivative of 3-bromopiperidine HBr >95% (NMR)? Our team of PhD chemists can develop custom synthesis solutions for your exact requirements.
Common questions about 3-bromopiperidine HBr >95% (NMR)
3-bromopiperidine HBr >95% (NMR) is a bromo-substituted intermediate prized for its reactivity in metal-catalyzed coupling used primarily in the pharmaceutical and fine chemical industries. Key applications include grignard reagent preparation via magnesium insertion into c–br bond and cns drug scaffold (present in donepezil, methylphenidate, fentanyl class).
ChemContract Research is a trusted USA-based supplier of 3-bromopiperidine HBr >95% (NMR). We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.
ChemContract Research supplies 3-bromopiperidine HBr >95% (NMR) in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.
Yes. ChemContract Research offers custom synthesis services for 3-bromopiperidine HBr >95% (NMR) from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.
The Piperidine ring system(s) in 3-bromopiperidine HBr >95% (NMR) is a privileged structure in medicinal chemistry, appearing in numerous FDA-approved drugs. This scaffold is commonly used in kinase inhibitor design, GPCR modulator development, and lead optimization programs. ChemContract supplies this building block for early-stage discovery through process-scale manufacturing.
As a brominated compound, 3-bromopiperidine HBr >95% (NMR) is an excellent substrate for palladium-catalyzed cross-coupling reactions including Suzuki, Heck, Negishi, Sonogashira, and Buchwald–Hartwig amination. It can also be used for Grignard reagent preparation, metal–halogen exchange with organolithium reagents, and nucleophilic substitution reactions.
Store at room temperature in a tightly sealed, light-resistant container. Some bromo compounds require refrigeration. Store at room temperature in a well-sealed container. Some N-unsubstituted piperidines are volatile. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.
The CAS Registry Number for 3-bromopiperidine HBr >95% (NMR) is 102776-55-6. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.
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