Frequently Asked
Common questions about 3-bromo-4-(2,4-difluorophenoxy)aniline hydrochloride
What is 3-bromo-4-(2,4-difluorophenoxy)aniline hydrochloride used for?
3-bromo-4-(2,4-difluorophenoxy)aniline hydrochloride is a fluorine-containing building block with enhanced metabolic stability used primarily in the pharmaceutical and diagnostic imaging industries. Key applications include metabolic blocking strategy — fluorine substitution to improve drug half-life and grignard reagent preparation via magnesium insertion into c–br bond.
Where can I buy 3-bromo-4-(2,4-difluorophenoxy)aniline hydrochloride in the USA?
ChemContract Research is a trusted USA-based supplier of 3-bromo-4-(2,4-difluorophenoxy)aniline hydrochloride. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.
What purity levels are available for 3-bromo-4-(2,4-difluorophenoxy)aniline hydrochloride?
ChemContract Research supplies 3-bromo-4-(2,4-difluorophenoxy)aniline hydrochloride in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.
Can ChemContract synthesize 3-bromo-4-(2,4-difluorophenoxy)aniline hydrochloride in custom quantities?
Yes. ChemContract Research offers custom synthesis services for 3-bromo-4-(2,4-difluorophenoxy)aniline hydrochloride from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.
Why is fluorine important in 3-bromo-4-(2,4-difluorophenoxy)aniline hydrochloride?
The fluorine atom(s) in 3-bromo-4-(2,4-difluorophenoxy)aniline hydrochloride confer several advantages in drug design: increased metabolic stability due to the strong C–F bond (485 kJ/mol), enhanced lipophilicity for improved membrane permeability, and potential for favorable electrostatic interactions with biological targets. These properties make fluorinated compounds like 3-bromo-4-(2,4-difluorophenoxy)aniline hydrochloride valuable in pharmaceutical development.
What coupling reactions can I run with 3-bromo-4-(2,4-difluorophenoxy)aniline hydrochloride?
As a brominated compound, 3-bromo-4-(2,4-difluorophenoxy)aniline hydrochloride is an excellent substrate for palladium-catalyzed cross-coupling reactions including Suzuki, Heck, Negishi, Sonogashira, and Buchwald–Hartwig amination. It can also be used for Grignard reagent preparation, metal–halogen exchange with organolithium reagents, and nucleophilic substitution reactions.
How should I store 3-bromo-4-(2,4-difluorophenoxy)aniline hydrochloride?
Store at recommended temperature in a tightly sealed container. Protect from moisture, heat, and incompatible materials. Store at room temperature in a tightly sealed, light-resistant container. Some bromo compounds require refrigeration. Store at room temperature in a tightly sealed container. Protect from humidity. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.
What is the CAS number of 3-bromo-4-(2,4-difluorophenoxy)aniline hydrochloride?
The CAS Registry Number for 3-bromo-4-(2,4-difluorophenoxy)aniline hydrochloride is 2007921-24-4. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.
