Amine · 2 functional traits · cGMP compliant · Ships from USA in 2-3 days
3-Amino-4-methylphenol is an amine-functionalized compound with nucleophilic nitrogen reactivity featuring a Benzene ring. ChemContract Research supplies this simple-complexity compound in high purity from our Huntington Beach, California facility, ensuring consistent quality and reliable domestic delivery throughout the United States.
Amines are among the most prevalent functional groups in drug molecules — over 80% of small-molecule pharmaceuticals contain at least one amine moiety. Hydroxyl groups are critical pharmacophores — they serve as hydrogen-bond donors and acceptors, influencing drug–target binding, aqueous solubility, and metabolic susceptibility.
Primary applications include buchwald–hartwig amination for aryl c–n bond construction and mitsunobu reaction substrate for stereospecific inversion at chiral centers. This compound serves researchers and manufacturers across the pharmaceutical, polymer, agrochemical sectors. Whether you require 3-Amino-4-methylphenol for early-stage research, process development, or commercial-scale production, ChemContract Research offers flexible ordering from milligram to multi-kilogram quantities with custom synthesis options and full batch documentation including Certificates of Analysis (CoA) and Safety Data Sheets.
How 3-Amino-4-methylphenol is used across pharmaceutical and polymer sectors
Buchwald–Hartwig amination for aryl C–N bond construction
Mitsunobu reaction substrate for stereospecific inversion at chiral centers
Reductive amination with aldehydes and ketones for secondary amine synthesis
Oxidation to aldehydes (Swern, Dess–Martin) or ketones for downstream chemistry
Salt formation to improve drug solubility and bioavailability
Ether formation via Williamson synthesis for drug analog SAR studies
Detailed specifications for this amine, including purity, molecular weight, and analytical data are available upon request. Every batch from ChemContract Research includes:
Amines may have strong odors and can be corrosive to skin. Handle under adequate ventilation with chemical-resistant gloves and eye protection. Handle with standard precautions. Some alcohols are flammable. Use adequate ventilation and appropriate PPE.
Store in a cool, well-ventilated area away from acids and oxidizing agents. Keep containers tightly sealed as many amines are hygroscopic. Store at room temperature in a tightly sealed container away from heat sources and oxidizers.
Amines are the most prevalent pharmacophore in drug molecules. 3-Amino-4-methylphenol is supplied with salt-form options and free-base conversion protocols.
Every batch of 3-Amino-4-methylphenol is produced under cGMP conditions with full CoA documentation, HPLC purity verification, and lot traceability.
Ship from our Huntington Beach, CA facility with 2-3 business day domestic delivery. No import delays, no customs fees, no tariff surprises.
Need a specific grade, quantity, or derivative of 3-Amino-4-methylphenol? Our team of PhD chemists can develop custom synthesis solutions for your exact requirements.
Common questions about 3-Amino-4-methylphenol
3-Amino-4-methylphenol is an amine-functionalized compound with nucleophilic nitrogen reactivity used primarily in the pharmaceutical and polymer industries. Key applications include buchwald–hartwig amination for aryl c–n bond construction and mitsunobu reaction substrate for stereospecific inversion at chiral centers.
ChemContract Research is a trusted USA-based supplier of 3-Amino-4-methylphenol. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.
ChemContract Research supplies 3-Amino-4-methylphenol in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.
Yes. ChemContract Research offers custom synthesis services for 3-Amino-4-methylphenol from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.
The amine functionality in 3-Amino-4-methylphenol enables diverse transformations: reductive amination with aldehydes/ketones, acylation to form amides, sulfonylation to form sulfonamides, Buchwald–Hartwig coupling with aryl halides, urea and carbamate formation, and salt generation for improved drug properties. The nucleophilicity of the nitrogen makes it one of the most versatile handles in synthetic chemistry.
Store in a cool, well-ventilated area away from acids and oxidizing agents. Keep containers tightly sealed as many amines are hygroscopic. Store at room temperature in a tightly sealed container away from heat sources and oxidizers. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.
Get competitive pricing, custom quantities, and fast USA delivery. Our chemistry team is standing by to provide specifications, CoA documentation, and a tailored quote for your project.
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