CAS 394735-23-0 · Amine · 5 functional traits · cGMP compliant · Ships from USA in 2-3 days
3-Amino-4-cyclobutyl-2-hydroxybutanamide HCL (CAS Number: 394735-23-0) is an amine-functionalized compound with nucleophilic nitrogen reactivity featuring a Cyclobutane ring with defined stereochemistry. ChemContract Research supplies this moderate-complexity compound in high purity from our Huntington Beach, California facility, ensuring consistent quality and reliable domestic delivery throughout the United States. Supplied as the hydrochloride salt form for enhanced stability and handling.
Amines are among the most prevalent functional groups in drug molecules — over 80% of small-molecule pharmaceuticals contain at least one amine moiety. Hydroxyl groups are critical pharmacophores — they serve as hydrogen-bond donors and acceptors, influencing drug–target binding, aqueous solubility, and metabolic susceptibility. The amide bond is the single most common functional group in pharmaceutical compounds — its partial double-bond character provides both rigidity and hydrogen-bonding capability essential for target engagement.
Primary applications include buchwald–hartwig amination for aryl c–n bond construction and mitsunobu reaction substrate for stereospecific inversion at chiral centers. This compound serves researchers and manufacturers across the pharmaceutical, polymer, agrochemical sectors. Whether you require 3-Amino-4-cyclobutyl-2-hydroxybutanamide HCL for early-stage research, process development, or commercial-scale production, ChemContract Research offers flexible ordering from milligram to multi-kilogram quantities with custom synthesis options and full batch documentation including Certificates of Analysis (CoA) and Safety Data Sheets.
How 3-Amino-4-cyclobutyl-2-hydroxybutanamide HCL is used across pharmaceutical and polymer sectors
Buchwald–Hartwig amination for aryl C–N bond construction
Mitsunobu reaction substrate for stereospecific inversion at chiral centers
Peptide bond mimetic for peptidomimetic drug design
Improved handling characteristics versus the free base form
Enantiopure building block for single-enantiomer drug development
Reductive amination with aldehydes and ketones for secondary amine synthesis
Detailed specifications for this amine, including purity, molecular weight, and analytical data are available upon request. Every batch from ChemContract Research includes:
Amines may have strong odors and can be corrosive to skin. Handle under adequate ventilation with chemical-resistant gloves and eye protection. Handle with standard precautions. Some alcohols are flammable. Use adequate ventilation and appropriate PPE. Handle with standard laboratory precautions. Consult the SDS for compound-specific hazards. Handle with standard precautions. Hydrochloride salts are generally more stable than free bases. Handle with standard precautions. Ensure proper labeling of stereochemical identity to prevent mix-ups.
Store in a cool, well-ventilated area away from acids and oxidizing agents. Keep containers tightly sealed as many amines are hygroscopic. Store at room temperature in a tightly sealed container away from heat sources and oxidizers. Store at room temperature or as specified. Keep tightly sealed and protect from moisture. Store at room temperature in a tightly sealed container. Protect from humidity. Store under recommended conditions. Some chiral compounds may racemize at elevated temperatures or in the presence of base.
Amines are the most prevalent pharmacophore in drug molecules. 3-Amino-4-cyclobutyl-2-hydroxybutanamide HCL is supplied with salt-form options and free-base conversion protocols.
Every batch of 3-Amino-4-cyclobutyl-2-hydroxybutanamide HCL is produced under cGMP conditions with full CoA documentation, HPLC purity verification, and lot traceability.
Ship from our Huntington Beach, CA facility with 2-3 business day domestic delivery. No import delays, no customs fees, no tariff surprises.
Need a specific grade, quantity, or derivative of 3-Amino-4-cyclobutyl-2-hydroxybutanamide HCL? Our team of PhD chemists can develop custom synthesis solutions for your exact requirements.
Common questions about 3-Amino-4-cyclobutyl-2-hydroxybutanamide HCL
3-Amino-4-cyclobutyl-2-hydroxybutanamide HCL is an amine-functionalized compound with nucleophilic nitrogen reactivity used primarily in the pharmaceutical and polymer industries. Key applications include buchwald–hartwig amination for aryl c–n bond construction and mitsunobu reaction substrate for stereospecific inversion at chiral centers.
ChemContract Research is a trusted USA-based supplier of 3-Amino-4-cyclobutyl-2-hydroxybutanamide HCL. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.
ChemContract Research supplies 3-Amino-4-cyclobutyl-2-hydroxybutanamide HCL in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.
Yes. ChemContract Research offers custom synthesis services for 3-Amino-4-cyclobutyl-2-hydroxybutanamide HCL from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.
ChemContract Research supplies 3-Amino-4-cyclobutyl-2-hydroxybutanamide HCL with verified enantiomeric or diastereomeric purity as documented in our Certificate of Analysis (CoA). Chiral HPLC analysis is standard for stereodefined compounds. We can provide material with ≥98% ee/de for demanding applications. Contact us for specific optical purity requirements.
The amine functionality in 3-Amino-4-cyclobutyl-2-hydroxybutanamide HCL enables diverse transformations: reductive amination with aldehydes/ketones, acylation to form amides, sulfonylation to form sulfonamides, Buchwald–Hartwig coupling with aryl halides, urea and carbamate formation, and salt generation for improved drug properties. The nucleophilicity of the nitrogen makes it one of the most versatile handles in synthetic chemistry.
Store in a cool, well-ventilated area away from acids and oxidizing agents. Keep containers tightly sealed as many amines are hygroscopic. Store at room temperature in a tightly sealed container away from heat sources and oxidizers. Store at room temperature or as specified. Keep tightly sealed and protect from moisture. Store at room temperature in a tightly sealed container. Protect from humidity. Store under recommended conditions. Some chiral compounds may racemize at elevated temperatures or in the presence of base. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.
The CAS Registry Number for 3-Amino-4-cyclobutyl-2-hydroxybutanamide HCL is 394735-23-0. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.
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