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3-amino-2-methyl-propionic acid ethyl ester

CAS 22560-81-2 · Amine · 4 functional traits · cGMP compliant · Ships from USA in 2-3 days

Amine

3-amino-2-methyl-propionic acid ethyl ester

Carboxylic Acids PharmaceuticalPolymerAgrochemicalCatalysisFine ChemicalGreen Chemistry
CAS Number 22560-81-2
Category Amine · Carboxylic Acid
Origin USA
Compliance cGMP

Questions? Contact our chemistry team:

chemistry@chem-contract.com | +1 (714) 732-8549
In stock — typically ships within 2-3 business days

About 3-amino-2-methyl-propionic acid ethyl ester

3-amino-2-methyl-propionic acid ethyl ester (CAS Number: 22560-81-2) is an amine-functionalized compound with nucleophilic nitrogen reactivity with defined stereochemistry. ChemContract Research supplies this moderate-complexity compound in high purity from our Huntington Beach, California facility, ensuring consistent quality and reliable domestic delivery throughout the United States.

Amines are among the most prevalent functional groups in drug molecules — over 80% of small-molecule pharmaceuticals contain at least one amine moiety. Carboxylic acids are among the most synthetically versatile functional groups — they can be converted to amides, esters, acid chlorides, anhydrides, alcohols, and aldehydes in a single step. Ester hydrolysis by cellular esterases is the most commonly exploited prodrug activation mechanism — enabling drugs that cannot cross biological membranes as free acids.

Primary applications include buchwald–hartwig amination for aryl c–n bond construction and amide bond formation via edc/hobt or hatu coupling in peptide synthesis. This compound serves researchers and manufacturers across the pharmaceutical, polymer, agrochemical sectors. Whether you require 3-amino-2-methyl-propionic acid ethyl ester for early-stage research, process development, or commercial-scale production, ChemContract Research offers flexible ordering from milligram to multi-kilogram quantities with custom synthesis options and full batch documentation including Certificates of Analysis (CoA) and Safety Data Sheets.

Functional Groups: Amine (–NH₂/–NHR)Carboxylic acid (–COOH)Ester (–COOR)
Stereochemistry: Defined Configuration

Amine Applications & Target Industries

How 3-amino-2-methyl-propionic acid ethyl ester is used across pharmaceutical and polymer sectors

01

Buchwald–Hartwig amination for aryl C–N bond construction

02

Amide bond formation via EDC/HOBt or HATU coupling in peptide synthesis

03

Prodrug development to mask carboxylic acids and improve membrane permeability

04

Enantiopure building block for single-enantiomer drug development

05

Reductive amination with aldehydes and ketones for secondary amine synthesis

06

Salt formation with amines to improve drug crystallinity and stability

Target Industries: PharmaceuticalPolymerAgrochemicalCatalysisFine ChemicalGreen Chemistry

3-amino-2-methyl-propionic acid ethyl ester Specifications

Detailed specifications for this amine, including purity, molecular weight, and analytical data are available upon request. Every batch from ChemContract Research includes:

  • Certificate of Analysis (CoA) with purity verification
  • HPLC, NMR, and/or mass spectrometry characterization data
  • Material Safety Data Sheet (MSDS/SDS)
  • Batch-specific documentation and lot traceability
  • Custom analytical testing available on request
Request Full Specifications

Quick Reference

Compound Name 3-amino-2-methyl-propionic acid ethyl ester
Type Amine
Category Amine · Carboxylic Acid
Purity ≥95% (custom grades available)
Stereochemistry Defined configuration (chiral HPLC verified)
Complexity Moderate (3 functional groups, 0 rings)
Compliance cGMP
Packaging mg to kg scale

Storage & Handling for Amines

Handling Guidelines

Amines may have strong odors and can be corrosive to skin. Handle under adequate ventilation with chemical-resistant gloves and eye protection. Acids may be corrosive or irritating. Handle with chemical-resistant gloves and eye protection. Use a fume hood for volatile acids. Some esters are volatile and flammable. Handle in a well-ventilated area. Keep away from ignition sources. Handle with standard precautions. Ensure proper labeling of stereochemical identity to prevent mix-ups.

Storage Conditions

Store in a cool, well-ventilated area away from acids and oxidizing agents. Keep containers tightly sealed as many amines are hygroscopic. Store at room temperature in a tightly sealed container. Protect from moisture and strong bases. Store at room temperature in a tightly sealed container away from heat and open flame. Store under recommended conditions. Some chiral compounds may racemize at elevated temperatures or in the presence of base.

Why Buy 3-amino-2-methyl-propionic acid ethyl ester From ChemContract?

Quality Assured

Every batch of 3-amino-2-methyl-propionic acid ethyl ester is produced under cGMP conditions with full CoA documentation, HPLC purity verification, and lot traceability.

Fast USA Shipping

Ship from our Huntington Beach, CA facility with 2-3 business day domestic delivery. No import delays, no customs fees, no tariff surprises.

Custom Synthesis

Need a specific grade, quantity, or derivative of 3-amino-2-methyl-propionic acid ethyl ester? Our team of PhD chemists can develop custom synthesis solutions for your exact requirements.

Frequently Asked

Common questions about 3-amino-2-methyl-propionic acid ethyl ester

What is 3-amino-2-methyl-propionic acid ethyl ester used for? +

3-amino-2-methyl-propionic acid ethyl ester is an amine-functionalized compound with nucleophilic nitrogen reactivity used primarily in the pharmaceutical and polymer industries. Key applications include buchwald–hartwig amination for aryl c–n bond construction and amide bond formation via edc/hobt or hatu coupling in peptide synthesis.

Where can I buy 3-amino-2-methyl-propionic acid ethyl ester in the USA? +

ChemContract Research is a trusted USA-based supplier of 3-amino-2-methyl-propionic acid ethyl ester. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.

What purity levels are available for 3-amino-2-methyl-propionic acid ethyl ester? +

ChemContract Research supplies 3-amino-2-methyl-propionic acid ethyl ester in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.

Can ChemContract synthesize 3-amino-2-methyl-propionic acid ethyl ester in custom quantities? +

Yes. ChemContract Research offers custom synthesis services for 3-amino-2-methyl-propionic acid ethyl ester from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.

What is the stereochemical purity of 3-amino-2-methyl-propionic acid ethyl ester? +

ChemContract Research supplies 3-amino-2-methyl-propionic acid ethyl ester with verified enantiomeric or diastereomeric purity as documented in our Certificate of Analysis (CoA). Chiral HPLC analysis is standard for stereodefined compounds. We can provide material with ≥98% ee/de for demanding applications. Contact us for specific optical purity requirements.

What reactions can I perform with the amine group in 3-amino-2-methyl-propionic acid ethyl ester? +

The amine functionality in 3-amino-2-methyl-propionic acid ethyl ester enables diverse transformations: reductive amination with aldehydes/ketones, acylation to form amides, sulfonylation to form sulfonamides, Buchwald–Hartwig coupling with aryl halides, urea and carbamate formation, and salt generation for improved drug properties. The nucleophilicity of the nitrogen makes it one of the most versatile handles in synthetic chemistry.

How should I store 3-amino-2-methyl-propionic acid ethyl ester? +

Store in a cool, well-ventilated area away from acids and oxidizing agents. Keep containers tightly sealed as many amines are hygroscopic. Store at room temperature in a tightly sealed container. Protect from moisture and strong bases. Store at room temperature in a tightly sealed container away from heat and open flame. Store under recommended conditions. Some chiral compounds may racemize at elevated temperatures or in the presence of base. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.

What is the CAS number of 3-amino-2-methyl-propionic acid ethyl ester? +

The CAS Registry Number for 3-amino-2-methyl-propionic acid ethyl ester is 22560-81-2. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.

Chemical analysis laboratory with HPLC instruments for purity and impurity testing Custom chemical synthesis reaction setup for pharmaceutical intermediate production

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