Search 7,000+ Chemicals

Start typing to search our catalog

2,4-Dichloro-5-iodopyrimidine 95%

CAS 13544-44-0 · Chlorinated Compound · 3 functional traits · cGMP compliant · Ships from USA in 2-3 days

Chlorinated Compound

2,4-Dichloro-5-iodopyrimidine 95%

Heterocycles PharmaceuticalAgrochemicalFine ChemicalChemical ManufacturingNuclear MedicineResearch
CAS Number 13544-44-0
Category Chlorinated Compound · Iodinated Compound
Origin USA
Compliance cGMP

Questions? Contact our chemistry team:

chemistry@chem-contract.com | +1 (714) 732-8549
In stock — typically ships within 2-3 business days

About 2,4-Dichloro-5-iodopyrimidine 95%

2,4-Dichloro-5-iodopyrimidine 95% (CAS Number: 13544-44-0) is a chloro-substituted intermediate widely used in nucleophilic displacement reactions featuring a Pyrimidine ring. ChemContract Research supplies this moderate-complexity compound in high purity from our Huntington Beach, California facility, ensuring consistent quality and reliable domestic delivery throughout the United States.

Chloro substituents serve a dual role in drug design — as synthetic handles for late-stage functionalization and as bioisosteres that modulate lipophilicity and binding affinity. The C–I bond is the weakest carbon–halogen bond, which translates to the highest reactivity in oxidative addition — making aryl iodides the first-choice substrate for challenging cross-coupling reactions. Heterocyclic rings appear in approximately 85% of all biologically active compounds. The nitrogen, oxygen, or sulfur heteroatom modulates electron density, hydrogen bonding, and aqueous solubility.

Primary applications include nucleophilic aromatic substitution (snar) for ether and amine formation and sonogashira and heck coupling with the lowest activation barrier among aryl halides. This compound serves researchers and manufacturers across the pharmaceutical, agrochemical, fine chemical sectors. Whether you require 2,4-Dichloro-5-iodopyrimidine 95% for early-stage research, process development, or commercial-scale production, ChemContract Research offers flexible ordering from milligram to multi-kilogram quantities with custom synthesis options and full batch documentation including Certificates of Analysis (CoA) and Safety Data Sheets.

Ring Systems: Pyrimidine
Functional Groups: Chlorine (C–Cl)Iodine (C–I)

Chlorinated Compound Applications & Target Industries

How 2,4-Dichloro-5-iodopyrimidine 95% is used across pharmaceutical and agrochemical sectors

01

Nucleophilic aromatic substitution (SNAr) for ether and amine formation

02

Sonogashira and Heck coupling with the lowest activation barrier among aryl halides

03

Core scaffold in kinase inhibitor design for oncology therapeutics

04

Grignard reagent precursor for C–C bond construction

05

Radioiodination precursor for SPECT and PET diagnostic imaging

06

GPCR modulator development for CNS and cardiovascular indications

Target Industries: PharmaceuticalAgrochemicalFine ChemicalChemical ManufacturingNuclear MedicineResearch

2,4-Dichloro-5-iodopyrimidine 95% Specifications

Detailed specifications for this chlorinated compound, including purity, molecular weight, and analytical data are available upon request. Every batch from ChemContract Research includes:

  • Certificate of Analysis (CoA) with purity verification
  • HPLC, NMR, and/or mass spectrometry characterization data
  • Material Safety Data Sheet (MSDS/SDS)
  • Batch-specific documentation and lot traceability
  • Custom analytical testing available on request
Request Full Specifications

Quick Reference

Compound Name 2,4-Dichloro-5-iodopyrimidine 95%
Type Chlorinated Compound
Category Chlorinated Compound · Iodinated Compound
Purity ≥95% (custom grades available)
Complexity Moderate (2 functional groups, 1 ring)
Compliance cGMP
Packaging mg to kg scale

Storage & Handling for Chlorinated Compounds

Handling Guidelines

Some chlorinated compounds are volatile or irritating. Use a fume hood and appropriate PPE. Acid chlorides react vigorously with water. Iodo compounds may be light-sensitive and can stain skin. Handle in a fume hood and protect from light during use. Handle with standard laboratory precautions. Some heterocycles may be hygroscopic or irritating. Use adequate ventilation.

Storage Conditions

Store at recommended temperature in a well-sealed container. Protect from moisture and strong bases. Store refrigerated (2–8 °C) in a light-resistant, tightly sealed container under inert atmosphere to prevent degradation. Store at recommended temperature in a tightly sealed container. Some heterocyclic compounds are light-sensitive.

Why Buy 2,4-Dichloro-5-iodopyrimidine 95% From ChemContract?

Quality Assured

Every batch of 2,4-Dichloro-5-iodopyrimidine 95% is produced under cGMP conditions with full CoA documentation, HPLC purity verification, and lot traceability.

Fast USA Shipping

Ship from our Huntington Beach, CA facility with 2-3 business day domestic delivery. No import delays, no customs fees, no tariff surprises.

Custom Synthesis

Need a specific grade, quantity, or derivative of 2,4-Dichloro-5-iodopyrimidine 95%? Our team of PhD chemists can develop custom synthesis solutions for your exact requirements.

Frequently Asked

Common questions about 2,4-Dichloro-5-iodopyrimidine 95%

What is 2,4-Dichloro-5-iodopyrimidine 95% used for? +

2,4-Dichloro-5-iodopyrimidine 95% is a chloro-substituted intermediate widely used in nucleophilic displacement reactions used primarily in the pharmaceutical and agrochemical industries. Key applications include nucleophilic aromatic substitution (snar) for ether and amine formation and sonogashira and heck coupling with the lowest activation barrier among aryl halides.

Where can I buy 2,4-Dichloro-5-iodopyrimidine 95% in the USA? +

ChemContract Research is a trusted USA-based supplier of 2,4-Dichloro-5-iodopyrimidine 95%. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.

What purity levels are available for 2,4-Dichloro-5-iodopyrimidine 95%? +

ChemContract Research supplies 2,4-Dichloro-5-iodopyrimidine 95% in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.

Can ChemContract synthesize 2,4-Dichloro-5-iodopyrimidine 95% in custom quantities? +

Yes. ChemContract Research offers custom synthesis services for 2,4-Dichloro-5-iodopyrimidine 95% from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.

What coupling reactions can I run with 2,4-Dichloro-5-iodopyrimidine 95%? +

As a chlorinated compound, 2,4-Dichloro-5-iodopyrimidine 95% is an excellent substrate for palladium-catalyzed cross-coupling reactions including Suzuki, Heck, Negishi, Sonogashira, and Buchwald–Hartwig amination. It can also be used for Grignard reagent preparation, metal–halogen exchange with organolithium reagents, and nucleophilic substitution reactions.

What drug discovery applications use 2,4-Dichloro-5-iodopyrimidine 95%? +

The Pyrimidine ring system(s) in 2,4-Dichloro-5-iodopyrimidine 95% is a privileged structure in medicinal chemistry, appearing in numerous FDA-approved drugs. This scaffold is commonly used in kinase inhibitor design, GPCR modulator development, and lead optimization programs. ChemContract supplies this building block for early-stage discovery through process-scale manufacturing.

How should I store 2,4-Dichloro-5-iodopyrimidine 95%? +

Store at recommended temperature in a well-sealed container. Protect from moisture and strong bases. Store refrigerated (2–8 °C) in a light-resistant, tightly sealed container under inert atmosphere to prevent degradation. Store at recommended temperature in a tightly sealed container. Some heterocyclic compounds are light-sensitive. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.

What is the CAS number of 2,4-Dichloro-5-iodopyrimidine 95%? +

The CAS Registry Number for 2,4-Dichloro-5-iodopyrimidine 95% is 13544-44-0. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.

Chemical analysis laboratory with HPLC instruments for purity and impurity testing Custom chemical synthesis reaction setup for pharmaceutical intermediate production

Get 2,4-Dichloro-5-iodopyrimidine 95% Delivered This Week

Get competitive pricing, custom quantities, and fast USA delivery. Our chemistry team is standing by to provide specifications, CoA documentation, and a tailored quote for your project.

Or call us directly: +1 (714) 732-8549

ChemContract

Let's Build
Your Molecule

From discovery to commercial scale — our 500+ scientists are ready to accelerate your project.

24-Hour ResponseFast turnaround guaranteed
60+ FacilitiesGlobal R&D network
cGMP CompliantFDA-ready manufacturing

Request a Quote

Tell us about your compound and we'll send a detailed quote within 24 hours.

Contact Information
Chemical Specifications
ChemContract
Mon-Fri 8AM-5PM PT

Hi there! How can we help you today?