CAS 5625-67-2 · Piperazine · cGMP compliant · Ships from USA in 2-3 days
2-Oxopiperazine (CAS Number: 5625-67-2) is a piperazine-containing compound used extensively as a pharmacokinetic-enhancing motif featuring a Piperazine ring. ChemContract Research supplies this simple-complexity compound in high purity from our Huntington Beach, California facility, ensuring consistent quality and reliable domestic delivery throughout the United States.
The two nitrogen atoms of piperazine provide both a basic amine (pKa ~9.8) for salt formation and a secondary amine (pKa ~5.3) for functionalization, giving medicinal chemists dual synthetic handles.
Primary applications include solubility enhancer via piperazine salt formation in drug formulation. This compound serves researchers and manufacturers across the pharmaceutical, cns therapeutics, medicinal chemistry sectors. Whether you require 2-Oxopiperazine for early-stage research, process development, or commercial-scale production, ChemContract Research offers flexible ordering from milligram to multi-kilogram quantities with custom synthesis options and full batch documentation including Certificates of Analysis (CoA) and Safety Data Sheets.
How 2-Oxopiperazine is used across pharmaceutical and cns therapeutics sectors
Solubility enhancer via piperazine salt formation in drug formulation
Bioisosteric replacement for piperidine to improve metabolic profile
Antipsychotic and anxiolytic drug scaffold (aripiprazole class)
Linker moiety in PROTACs and bifunctional degrader molecules
Detailed specifications for this piperazine, including purity, molecular weight, and analytical data are available upon request. Every batch from ChemContract Research includes:
Handle with standard precautions. Some piperazine derivatives may be irritating. Use adequate ventilation.
Store at room temperature in a tightly sealed container away from acids.
Piperazine motifs improve drug solubility. 2-Oxopiperazine is available with salt-form screening data to accelerate your formulation development.
Every batch of 2-Oxopiperazine is produced under cGMP conditions with full CoA documentation, HPLC purity verification, and lot traceability.
Ship from our Huntington Beach, CA facility with 2-3 business day domestic delivery. No import delays, no customs fees, no tariff surprises.
Need a specific grade, quantity, or derivative of 2-Oxopiperazine? Our team of PhD chemists can develop custom synthesis solutions for your exact requirements.
Common questions about 2-Oxopiperazine
2-Oxopiperazine is a piperazine-containing compound used extensively as a pharmacokinetic-enhancing motif used primarily in the pharmaceutical and cns therapeutics industries. Key applications include solubility enhancer via piperazine salt formation in drug formulation and bioisosteric replacement for piperidine to improve metabolic profile.
ChemContract Research is a trusted USA-based supplier of 2-Oxopiperazine. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.
ChemContract Research supplies 2-Oxopiperazine in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.
Yes. ChemContract Research offers custom synthesis services for 2-Oxopiperazine from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.
The Piperazine ring system(s) in 2-Oxopiperazine is a privileged structure in medicinal chemistry, appearing in numerous FDA-approved drugs. This scaffold is commonly used in kinase inhibitor design, GPCR modulator development, and lead optimization programs. ChemContract supplies this building block for early-stage discovery through process-scale manufacturing.
Store at room temperature in a tightly sealed container away from acids. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.
The CAS Registry Number for 2-Oxopiperazine is 5625-67-2. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.
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