Search 7,000+ Chemicals

Start typing to search our catalog

2-Oxopiperazine

CAS 5625-67-2 · Piperazine · cGMP compliant · Ships from USA in 2-3 days

Piperazine

2-Oxopiperazine

Piperidines PharmaceuticalCNS TherapeuticsMedicinal ChemistryDrug Delivery
CAS Number 5625-67-2
Category Piperazine
Origin USA
Compliance cGMP

Questions? Contact our chemistry team:

chemistry@chem-contract.com | +1 (714) 732-8549
In stock — typically ships within 2-3 business days

About 2-Oxopiperazine

2-Oxopiperazine (CAS Number: 5625-67-2) is a piperazine-containing compound used extensively as a pharmacokinetic-enhancing motif featuring a Piperazine ring. ChemContract Research supplies this simple-complexity compound in high purity from our Huntington Beach, California facility, ensuring consistent quality and reliable domestic delivery throughout the United States.

The two nitrogen atoms of piperazine provide both a basic amine (pKa ~9.8) for salt formation and a secondary amine (pKa ~5.3) for functionalization, giving medicinal chemists dual synthetic handles.

Primary applications include solubility enhancer via piperazine salt formation in drug formulation. This compound serves researchers and manufacturers across the pharmaceutical, cns therapeutics, medicinal chemistry sectors. Whether you require 2-Oxopiperazine for early-stage research, process development, or commercial-scale production, ChemContract Research offers flexible ordering from milligram to multi-kilogram quantities with custom synthesis options and full batch documentation including Certificates of Analysis (CoA) and Safety Data Sheets.

Ring Systems: Piperazine

Piperazine Applications & Target Industries

How 2-Oxopiperazine is used across pharmaceutical and cns therapeutics sectors

01

Solubility enhancer via piperazine salt formation in drug formulation

02

Bioisosteric replacement for piperidine to improve metabolic profile

03

Antipsychotic and anxiolytic drug scaffold (aripiprazole class)

04

Linker moiety in PROTACs and bifunctional degrader molecules

Target Industries: PharmaceuticalCNS TherapeuticsMedicinal ChemistryDrug Delivery

2-Oxopiperazine Specifications

Detailed specifications for this piperazine, including purity, molecular weight, and analytical data are available upon request. Every batch from ChemContract Research includes:

  • Certificate of Analysis (CoA) with purity verification
  • HPLC, NMR, and/or mass spectrometry characterization data
  • Material Safety Data Sheet (MSDS/SDS)
  • Batch-specific documentation and lot traceability
  • Custom analytical testing available on request
Request Full Specifications

Quick Reference

Compound Name 2-Oxopiperazine
Type Piperazine
Category Piperazine
Purity ≥95% (custom grades available)
Complexity Simple (0 functional groups, 1 ring)
Compliance cGMP
Packaging mg to kg scale

Storage & Handling for Piperazines

Handling Guidelines

Handle with standard precautions. Some piperazine derivatives may be irritating. Use adequate ventilation.

Storage Conditions

Store at room temperature in a tightly sealed container away from acids.

Why Buy 2-Oxopiperazine From ChemContract?

Quality Assured

Every batch of 2-Oxopiperazine is produced under cGMP conditions with full CoA documentation, HPLC purity verification, and lot traceability.

Fast USA Shipping

Ship from our Huntington Beach, CA facility with 2-3 business day domestic delivery. No import delays, no customs fees, no tariff surprises.

Custom Synthesis

Need a specific grade, quantity, or derivative of 2-Oxopiperazine? Our team of PhD chemists can develop custom synthesis solutions for your exact requirements.

Frequently Asked

Common questions about 2-Oxopiperazine

What is 2-Oxopiperazine used for? +

2-Oxopiperazine is a piperazine-containing compound used extensively as a pharmacokinetic-enhancing motif used primarily in the pharmaceutical and cns therapeutics industries. Key applications include solubility enhancer via piperazine salt formation in drug formulation and bioisosteric replacement for piperidine to improve metabolic profile.

Where can I buy 2-Oxopiperazine in the USA? +

ChemContract Research is a trusted USA-based supplier of 2-Oxopiperazine. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.

What purity levels are available for 2-Oxopiperazine? +

ChemContract Research supplies 2-Oxopiperazine in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.

Can ChemContract synthesize 2-Oxopiperazine in custom quantities? +

Yes. ChemContract Research offers custom synthesis services for 2-Oxopiperazine from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.

What drug discovery applications use 2-Oxopiperazine? +

The Piperazine ring system(s) in 2-Oxopiperazine is a privileged structure in medicinal chemistry, appearing in numerous FDA-approved drugs. This scaffold is commonly used in kinase inhibitor design, GPCR modulator development, and lead optimization programs. ChemContract supplies this building block for early-stage discovery through process-scale manufacturing.

How should I store 2-Oxopiperazine? +

Store at room temperature in a tightly sealed container away from acids. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.

What is the CAS number of 2-Oxopiperazine? +

The CAS Registry Number for 2-Oxopiperazine is 5625-67-2. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.

Chemical analysis laboratory with HPLC instruments for purity and impurity testing Custom chemical synthesis reaction setup for pharmaceutical intermediate production

Get 2-Oxopiperazine Delivered This Week

Get competitive pricing, custom quantities, and fast USA delivery. Our chemistry team is standing by to provide specifications, CoA documentation, and a tailored quote for your project.

Or call us directly: +1 (714) 732-8549

ChemContract

Let's Build
Your Molecule

From discovery to commercial scale — our 500+ scientists are ready to accelerate your project.

24-Hour ResponseFast turnaround guaranteed
60+ FacilitiesGlobal R&D network
cGMP CompliantFDA-ready manufacturing

Request a Quote

Tell us about your compound and we'll send a detailed quote within 24 hours.

Contact Information
Chemical Specifications
ChemContract
Mon-Fri 8AM-5PM PT

Hi there! How can we help you today?