Frequently Asked
Common questions about 2-Methylindole-3-acetic acid
What is 2-Methylindole-3-acetic acid used for?
2-Methylindole-3-acetic acid is a heterocycle-containing compound — the dominant scaffold class in approved pharmaceuticals used primarily in the pharmaceutical and medicinal chemistry industries. Key applications include core scaffold in kinase inhibitor design for oncology therapeutics and amide bond formation via edc/hobt or hatu coupling in peptide synthesis.
Where can I buy 2-Methylindole-3-acetic acid in the USA?
ChemContract Research is a trusted USA-based supplier of 2-Methylindole-3-acetic acid. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.
What purity levels are available for 2-Methylindole-3-acetic acid?
ChemContract Research supplies 2-Methylindole-3-acetic acid in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.
Can ChemContract synthesize 2-Methylindole-3-acetic acid in custom quantities?
Yes. ChemContract Research offers custom synthesis services for 2-Methylindole-3-acetic acid from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.
What coupling reagents work best with 2-Methylindole-3-acetic acid?
For amide bond formation from the carboxylic acid in 2-Methylindole-3-acetic acid, HATU/DIPEA is recommended for peptide coupling (high yield, low epimerization). EDC/HOBt is a cost-effective alternative for non-peptide amides. T3P (propylphosphonic acid anhydride) offers excellent atom economy with easy workup. For ester formation, DCC/DMAP (Steglich conditions) or Mitsunobu conditions are standard.
What drug discovery applications use 2-Methylindole-3-acetic acid?
The Indole ring system(s) in 2-Methylindole-3-acetic acid is a privileged structure in medicinal chemistry, appearing in numerous FDA-approved drugs. This scaffold is commonly used in kinase inhibitor design, GPCR modulator development, and lead optimization programs. ChemContract supplies this building block for early-stage discovery through process-scale manufacturing.
How should I store 2-Methylindole-3-acetic acid?
Store at recommended temperature in a tightly sealed container. Some heterocyclic compounds are light-sensitive. Store at room temperature in a tightly sealed container. Protect from moisture and strong bases. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.
What is the CAS number of 2-Methylindole-3-acetic acid?
The CAS Registry Number for 2-Methylindole-3-acetic acid is 1912-43-2. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.
