Boronic Acid / Boronate Ester · 2 functional traits · cGMP compliant · Ships from USA in 2-3 days
{2-methyl-2H-pyrazolo[3,4-b]pyridin-5-yl}boronic acid is a boronic acid derivative valued for its role in carbon–carbon bond-forming reactions featuring Pyridine, Pyrazole ring systems with defined stereochemistry. ChemContract Research supplies this moderate-complexity compound in high purity from our Huntington Beach, California facility, ensuring consistent quality and reliable domestic delivery throughout the United States.
The boron atom in this compound enables transmetalation with palladium catalysts, making it a cornerstone reagent for Suzuki coupling — one of the most widely used reactions in pharmaceutical process chemistry. Chirality matters profoundly in drug action — enantiomers can differ by orders of magnitude in potency, and FDA guidelines increasingly require single-enantiomer development.
Primary applications include suzuki–miyaura cross-coupling for biaryl and heterobiaryl synthesis and enantiopure building block for single-enantiomer drug development. This compound serves researchers and manufacturers across the pharmaceutical, medicinal chemistry, diagnostics sectors. Whether you require {2-methyl-2H-pyrazolo[3,4-b]pyridin-5-yl}boronic acid for early-stage research, process development, or commercial-scale production, ChemContract Research offers flexible ordering from milligram to multi-kilogram quantities with custom synthesis options and full batch documentation including Certificates of Analysis (CoA) and Safety Data Sheets.
How {2-methyl-2H-pyrazolo[3,4-b]pyridin-5-yl}boronic acid is used across pharmaceutical and medicinal chemistry sectors
Suzuki–Miyaura cross-coupling for biaryl and heterobiaryl synthesis
Enantiopure building block for single-enantiomer drug development
Proteasome inhibitor design in oncology drug development
Chiral resolution standard or chiral HPLC reference compound
Saccharide and diol sensor development for diagnostic applications
Asymmetric synthesis substrate with defined stereochemistry
Detailed specifications for this boronic acid / boronate ester, including purity, molecular weight, and analytical data are available upon request. Every batch from ChemContract Research includes:
Boronic acids are generally air-stable but some may be moisture-sensitive and undergo protodeboronation. Handle with gloves and safety glasses. Handle with standard precautions. Ensure proper labeling of stereochemical identity to prevent mix-ups.
Store in a tightly sealed container at room temperature under dry conditions. Protect from prolonged moisture exposure. Store under recommended conditions. Some chiral compounds may racemize at elevated temperatures or in the presence of base.
Our chemists optimize Suzuki and Chan–Lam coupling conditions for boronic acid building blocks like {2-methyl-2H-pyrazolo[3,4-b]pyridin-5-yl}boronic acid. Get application support alongside your order.
Every batch of {2-methyl-2H-pyrazolo[3,4-b]pyridin-5-yl}boronic acid is produced under cGMP conditions with full CoA documentation, HPLC purity verification, and lot traceability.
Ship from our Huntington Beach, CA facility with 2-3 business day domestic delivery. No import delays, no customs fees, no tariff surprises.
Need a specific grade, quantity, or derivative of {2-methyl-2H-pyrazolo[3,4-b]pyridin-5-yl}boronic acid? Our team of PhD chemists can develop custom synthesis solutions for your exact requirements.
Common questions about {2-methyl-2H-pyrazolo[3,4-b]pyridin-5-yl}boronic acid
{2-methyl-2H-pyrazolo[3,4-b]pyridin-5-yl}boronic acid is a boronic acid derivative valued for its role in carbon–carbon bond-forming reactions used primarily in the pharmaceutical and medicinal chemistry industries. Key applications include suzuki–miyaura cross-coupling for biaryl and heterobiaryl synthesis and enantiopure building block for single-enantiomer drug development.
ChemContract Research is a trusted USA-based supplier of {2-methyl-2H-pyrazolo[3,4-b]pyridin-5-yl}boronic acid. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.
ChemContract Research supplies {2-methyl-2H-pyrazolo[3,4-b]pyridin-5-yl}boronic acid in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.
Yes. ChemContract Research offers custom synthesis services for {2-methyl-2H-pyrazolo[3,4-b]pyridin-5-yl}boronic acid from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.
{2-methyl-2H-pyrazolo[3,4-b]pyridin-5-yl}boronic acid is primarily used in Suzuki–Miyaura cross-coupling reactions with aryl or vinyl halides under palladium catalysis. This reaction forms C–C bonds with excellent functional group tolerance and mild conditions. It can also be used in Chan–Lam coupling for C–N and C–O bond formation without transition metal catalysts under aerobic conditions.
ChemContract Research supplies {2-methyl-2H-pyrazolo[3,4-b]pyridin-5-yl}boronic acid with verified enantiomeric or diastereomeric purity as documented in our Certificate of Analysis (CoA). Chiral HPLC analysis is standard for stereodefined compounds. We can provide material with ≥98% ee/de for demanding applications. Contact us for specific optical purity requirements.
Store in a tightly sealed container at room temperature under dry conditions. Protect from prolonged moisture exposure. Store under recommended conditions. Some chiral compounds may racemize at elevated temperatures or in the presence of base. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.
Get competitive pricing, custom quantities, and fast USA delivery. Our chemistry team is standing by to provide specifications, CoA documentation, and a tailored quote for your project.
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