2-Chloromethyl-3-Methyl-4-(2,2,2-Trifluoroethoxy)Pyridine Hcl

2-Chloromethyl-3-Methyl-4-(2,2,2-Trifluoroethoxy)Pyridine Hcl is a fluorine-containing building block with enhanced metabolic stability used primarily in the pharmaceutical and diagnostic imaging industries. Key applications include metabolic blocking strategy — fluorine substitution to improve drug half-life and nucleophilic aromatic substitution (snar) for ether and amine formation.

ChemContract Research is a trusted USA-based supplier of 2-Chloromethyl-3-Methyl-4-(2,2,2-Trifluoroethoxy)Pyridine Hcl. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.

ChemContract Research supplies 2-Chloromethyl-3-Methyl-4-(2,2,2-Trifluoroethoxy)Pyridine Hcl in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.

Yes. ChemContract Research offers custom synthesis services for 2-Chloromethyl-3-Methyl-4-(2,2,2-Trifluoroethoxy)Pyridine Hcl from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.

Yes. ChemContract Research can supply 2-Chloromethyl-3-Methyl-4-(2,2,2-Trifluoroethoxy)Pyridine Hcl as the free base or convert it to alternative salt forms including hydrochloride, mesylate, tosylate, fumarate, or other pharmaceutically acceptable counter-ions. Salt form selection impacts crystallinity, stability, and solubility — our chemistry team can advise on optimal salt selection for your application. Currently supplied as the Hydrochloride form.

As a chlorinated compound, 2-Chloromethyl-3-Methyl-4-(2,2,2-Trifluoroethoxy)Pyridine Hcl is an excellent substrate for palladium-catalyzed cross-coupling reactions including Suzuki, Heck, Negishi, Sonogashira, and Buchwald–Hartwig amination. It can also be used for Grignard reagent preparation, metal–halogen exchange with organolithium reagents, and nucleophilic substitution reactions.

Store at recommended temperature in a tightly sealed container. Protect from moisture, heat, and incompatible materials. Store at recommended temperature in a well-sealed container. Protect from moisture and strong bases. Store at recommended temperature in a tightly sealed container. Some heterocyclic compounds are light-sensitive. Store at room temperature in a tightly sealed container. Protect from humidity. Store under recommended conditions. Some chiral compounds may racemize at elevated temperatures or in the presence of base. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.

The CAS Registry Number for 2-Chloromethyl-3-Methyl-4-(2,2,2-Trifluoroethoxy)Pyridine Hcl is 127337-60-4. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.