Search 7,000+ Chemicals

Start typing to search our catalog

2-Chloro Pyridine-N-Oxide Hcl

CAS 20295-64-1 · Chlorinated Compound · 3 functional traits · cGMP compliant · Ships from USA in 2-3 days

Chlorinated Compound

2-Chloro Pyridine-N-Oxide Hcl

Heterocycles PharmaceuticalAgrochemicalFine ChemicalChemical ManufacturingMedicinal ChemistryCatalysis
CAS Number 20295-64-1
Category Chlorinated Compound · Heterocyclic Compound
Origin USA
Compliance cGMP

Questions? Contact our chemistry team:

chemistry@chem-contract.com | +1 (714) 732-8549
In stock — typically ships within 2-3 business days

About 2-Chloro Pyridine-N-Oxide Hcl

2-Chloro Pyridine-N-Oxide Hcl (CAS Number: 20295-64-1) is a chloro-substituted intermediate widely used in nucleophilic displacement reactions featuring a Pyridine ring. ChemContract Research supplies this simple-complexity compound in high purity from our Huntington Beach, California facility, ensuring consistent quality and reliable domestic delivery throughout the United States. Supplied as the hydrochloride salt form for enhanced stability and handling.

Chloro substituents serve a dual role in drug design — as synthetic handles for late-stage functionalization and as bioisosteres that modulate lipophilicity and binding affinity. Heterocyclic rings appear in approximately 85% of all biologically active compounds. The nitrogen, oxygen, or sulfur heteroatom modulates electron density, hydrogen bonding, and aqueous solubility. Hydrochloride is the most common salt form for basic drug substances — approximately half of all salt-form drugs on the market are HCl salts, valued for their crystallinity and aqueous solubility.

Primary applications include nucleophilic aromatic substitution (snar) for ether and amine formation and core scaffold in kinase inhibitor design for oncology therapeutics. This compound serves researchers and manufacturers across the pharmaceutical, agrochemical, fine chemical sectors. Whether you require 2-Chloro Pyridine-N-Oxide Hcl for early-stage research, process development, or commercial-scale production, ChemContract Research offers flexible ordering from milligram to multi-kilogram quantities with custom synthesis options and full batch documentation including Certificates of Analysis (CoA) and Safety Data Sheets.

Ring Systems: Pyridine
Functional Groups: Chlorine (C–Cl)
Salt Form: Hydrochloride

Chlorinated Compound Applications & Target Industries

How 2-Chloro Pyridine-N-Oxide Hcl is used across pharmaceutical and agrochemical sectors

01

Nucleophilic aromatic substitution (SNAr) for ether and amine formation

02

Core scaffold in kinase inhibitor design for oncology therapeutics

03

Improved handling characteristics versus the free base form

04

Grignard reagent precursor for C–C bond construction

05

GPCR modulator development for CNS and cardiovascular indications

06

Direct formulation excipient in oral solid dosage forms

Target Industries: PharmaceuticalAgrochemicalFine ChemicalChemical ManufacturingMedicinal ChemistryCatalysis

2-Chloro Pyridine-N-Oxide Hcl Specifications

Detailed specifications for this chlorinated compound, including purity, molecular weight, and analytical data are available upon request. Every batch from ChemContract Research includes:

  • Certificate of Analysis (CoA) with purity verification
  • HPLC, NMR, and/or mass spectrometry characterization data
  • Material Safety Data Sheet (MSDS/SDS)
  • Batch-specific documentation and lot traceability
  • Custom analytical testing available on request
Request Full Specifications

Quick Reference

Compound Name 2-Chloro Pyridine-N-Oxide Hcl
Type Chlorinated Compound
Category Chlorinated Compound · Heterocyclic Compound
Purity ≥95% (custom grades available)
Salt Form Hydrochloride
Complexity Simple (1 functional groups, 1 ring)
Compliance cGMP
Packaging mg to kg scale

Storage & Handling for Chlorinated Compounds

Handling Guidelines

Some chlorinated compounds are volatile or irritating. Use a fume hood and appropriate PPE. Acid chlorides react vigorously with water. Handle with standard laboratory precautions. Some heterocycles may be hygroscopic or irritating. Use adequate ventilation. Handle with standard precautions. Hydrochloride salts are generally more stable than free bases.

Storage Conditions

Store at recommended temperature in a well-sealed container. Protect from moisture and strong bases. Store at recommended temperature in a tightly sealed container. Some heterocyclic compounds are light-sensitive. Store at room temperature in a tightly sealed container. Protect from humidity.

Why Buy 2-Chloro Pyridine-N-Oxide Hcl From ChemContract?

Quality Assured

Every batch of 2-Chloro Pyridine-N-Oxide Hcl is produced under cGMP conditions with full CoA documentation, HPLC purity verification, and lot traceability.

Fast USA Shipping

Ship from our Huntington Beach, CA facility with 2-3 business day domestic delivery. No import delays, no customs fees, no tariff surprises.

Custom Synthesis

Need a specific grade, quantity, or derivative of 2-Chloro Pyridine-N-Oxide Hcl? Our team of PhD chemists can develop custom synthesis solutions for your exact requirements.

Frequently Asked

Common questions about 2-Chloro Pyridine-N-Oxide Hcl

What is 2-Chloro Pyridine-N-Oxide Hcl used for? +

2-Chloro Pyridine-N-Oxide Hcl is a chloro-substituted intermediate widely used in nucleophilic displacement reactions used primarily in the pharmaceutical and agrochemical industries. Key applications include nucleophilic aromatic substitution (snar) for ether and amine formation and core scaffold in kinase inhibitor design for oncology therapeutics.

Where can I buy 2-Chloro Pyridine-N-Oxide Hcl in the USA? +

ChemContract Research is a trusted USA-based supplier of 2-Chloro Pyridine-N-Oxide Hcl. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.

What purity levels are available for 2-Chloro Pyridine-N-Oxide Hcl? +

ChemContract Research supplies 2-Chloro Pyridine-N-Oxide Hcl in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.

Can ChemContract synthesize 2-Chloro Pyridine-N-Oxide Hcl in custom quantities? +

Yes. ChemContract Research offers custom synthesis services for 2-Chloro Pyridine-N-Oxide Hcl from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.

Can I get 2-Chloro Pyridine-N-Oxide Hcl in a different salt form or as the free base? +

Yes. ChemContract Research can supply 2-Chloro Pyridine-N-Oxide Hcl as the free base or convert it to alternative salt forms including hydrochloride, mesylate, tosylate, fumarate, or other pharmaceutically acceptable counter-ions. Salt form selection impacts crystallinity, stability, and solubility — our chemistry team can advise on optimal salt selection for your application. Currently supplied as the Hydrochloride form.

What coupling reactions can I run with 2-Chloro Pyridine-N-Oxide Hcl? +

As a chlorinated compound, 2-Chloro Pyridine-N-Oxide Hcl is an excellent substrate for palladium-catalyzed cross-coupling reactions including Suzuki, Heck, Negishi, Sonogashira, and Buchwald–Hartwig amination. It can also be used for Grignard reagent preparation, metal–halogen exchange with organolithium reagents, and nucleophilic substitution reactions.

How should I store 2-Chloro Pyridine-N-Oxide Hcl? +

Store at recommended temperature in a well-sealed container. Protect from moisture and strong bases. Store at recommended temperature in a tightly sealed container. Some heterocyclic compounds are light-sensitive. Store at room temperature in a tightly sealed container. Protect from humidity. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.

What is the CAS number of 2-Chloro Pyridine-N-Oxide Hcl? +

The CAS Registry Number for 2-Chloro Pyridine-N-Oxide Hcl is 20295-64-1. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.

Chemical analysis laboratory with HPLC instruments for purity and impurity testing Custom chemical synthesis reaction setup for pharmaceutical intermediate production

Get 2-Chloro Pyridine-N-Oxide Hcl Delivered This Week

Get competitive pricing, custom quantities, and fast USA delivery. Our chemistry team is standing by to provide specifications, CoA documentation, and a tailored quote for your project.

Or call us directly: +1 (714) 732-8549

ChemContract

Let's Build
Your Molecule

From discovery to commercial scale — our 500+ scientists are ready to accelerate your project.

24-Hour ResponseFast turnaround guaranteed
60+ FacilitiesGlobal R&D network
cGMP CompliantFDA-ready manufacturing

Request a Quote

Tell us about your compound and we'll send a detailed quote within 24 hours.

Contact Information
Chemical Specifications
ChemContract
Mon-Fri 8AM-5PM PT

Hi there! How can we help you today?