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2-Chloro-indole-3-carbaldehyde 95%

CAS 5059-30-3 · Aldehyde · 3 functional traits · cGMP compliant · Ships from USA in 2-3 days

Aldehyde

2-Chloro-indole-3-carbaldehyde 95%

Heterocycles PharmaceuticalFragrance & FlavorFine ChemicalResearchAgrochemicalChemical Manufacturing
CAS Number 5059-30-3
Category Aldehyde · Chlorinated Compound
Origin USA
Compliance cGMP

Questions? Contact our chemistry team:

chemistry@chem-contract.com | +1 (714) 732-8549
In stock — typically ships within 2-3 business days

About 2-Chloro-indole-3-carbaldehyde 95%

2-Chloro-indole-3-carbaldehyde 95% (CAS Number: 5059-30-3) is an aldehyde with a highly electrophilic carbonyl group featuring a Indole ring. ChemContract Research supplies this moderate-complexity compound in high purity from our Huntington Beach, California facility, ensuring consistent quality and reliable domestic delivery throughout the United States.

The aldehyde carbonyl is one of the most reactive electrophilic centers in organic chemistry, enabling diverse transformations from imine formation to asymmetric allylation. Chloro substituents serve a dual role in drug design — as synthetic handles for late-stage functionalization and as bioisosteres that modulate lipophilicity and binding affinity. Heterocyclic rings appear in approximately 85% of all biologically active compounds. The nitrogen, oxygen, or sulfur heteroatom modulates electron density, hydrogen bonding, and aqueous solubility.

Primary applications include reductive amination for c–n bond formation in api synthesis and nucleophilic aromatic substitution (snar) for ether and amine formation. This compound serves researchers and manufacturers across the pharmaceutical, fragrance & flavor, fine chemical sectors. Whether you require 2-Chloro-indole-3-carbaldehyde 95% for early-stage research, process development, or commercial-scale production, ChemContract Research offers flexible ordering from milligram to multi-kilogram quantities with custom synthesis options and full batch documentation including Certificates of Analysis (CoA) and Safety Data Sheets.

Ring Systems: Indole
Functional Groups: Aldehyde (–CHO)Chlorine (C–Cl)

Aldehyde Applications & Target Industries

How 2-Chloro-indole-3-carbaldehyde 95% is used across pharmaceutical and fragrance & flavor sectors

01

Reductive amination for C–N bond formation in API synthesis

02

Nucleophilic aromatic substitution (SNAr) for ether and amine formation

03

Core scaffold in kinase inhibitor design for oncology therapeutics

04

Wittig and Horner–Wadsworth–Emmons olefination substrates

05

Grignard reagent precursor for C–C bond construction

06

GPCR modulator development for CNS and cardiovascular indications

Target Industries: PharmaceuticalFragrance & FlavorFine ChemicalResearchAgrochemicalChemical Manufacturing

2-Chloro-indole-3-carbaldehyde 95% Specifications

Detailed specifications for this aldehyde, including purity, molecular weight, and analytical data are available upon request. Every batch from ChemContract Research includes:

  • Certificate of Analysis (CoA) with purity verification
  • HPLC, NMR, and/or mass spectrometry characterization data
  • Material Safety Data Sheet (MSDS/SDS)
  • Batch-specific documentation and lot traceability
  • Custom analytical testing available on request
Request Full Specifications

Quick Reference

Compound Name 2-Chloro-indole-3-carbaldehyde 95%
Type Aldehyde
Category Aldehyde · Chlorinated Compound
Purity ≥95% (custom grades available)
Complexity Moderate (2 functional groups, 1 ring)
Compliance cGMP
Packaging mg to kg scale

Storage & Handling for Aldehydes

Handling Guidelines

Aldehydes can be irritating to skin, eyes, and respiratory tract. Handle in a well-ventilated fume hood. Many are volatile and flammable. Some chlorinated compounds are volatile or irritating. Use a fume hood and appropriate PPE. Acid chlorides react vigorously with water. Handle with standard laboratory precautions. Some heterocycles may be hygroscopic or irritating. Use adequate ventilation.

Storage Conditions

Store at recommended temperature under inert atmosphere. Protect from air to prevent oxidation to the corresponding carboxylic acid. Store at recommended temperature in a well-sealed container. Protect from moisture and strong bases. Store at recommended temperature in a tightly sealed container. Some heterocyclic compounds are light-sensitive.

Why Buy 2-Chloro-indole-3-carbaldehyde 95% From ChemContract?

Quality Assured

Every batch of 2-Chloro-indole-3-carbaldehyde 95% is produced under cGMP conditions with full CoA documentation, HPLC purity verification, and lot traceability.

Fast USA Shipping

Ship from our Huntington Beach, CA facility with 2-3 business day domestic delivery. No import delays, no customs fees, no tariff surprises.

Custom Synthesis

Need a specific grade, quantity, or derivative of 2-Chloro-indole-3-carbaldehyde 95%? Our team of PhD chemists can develop custom synthesis solutions for your exact requirements.

Frequently Asked

Common questions about 2-Chloro-indole-3-carbaldehyde 95%

What is 2-Chloro-indole-3-carbaldehyde 95% used for? +

2-Chloro-indole-3-carbaldehyde 95% is an aldehyde with a highly electrophilic carbonyl group used primarily in the pharmaceutical and fragrance & flavor industries. Key applications include reductive amination for c–n bond formation in api synthesis and nucleophilic aromatic substitution (snar) for ether and amine formation.

Where can I buy 2-Chloro-indole-3-carbaldehyde 95% in the USA? +

ChemContract Research is a trusted USA-based supplier of 2-Chloro-indole-3-carbaldehyde 95%. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.

What purity levels are available for 2-Chloro-indole-3-carbaldehyde 95%? +

ChemContract Research supplies 2-Chloro-indole-3-carbaldehyde 95% in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.

Can ChemContract synthesize 2-Chloro-indole-3-carbaldehyde 95% in custom quantities? +

Yes. ChemContract Research offers custom synthesis services for 2-Chloro-indole-3-carbaldehyde 95% from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.

What coupling reactions can I run with 2-Chloro-indole-3-carbaldehyde 95%? +

As a chlorinated compound, 2-Chloro-indole-3-carbaldehyde 95% is an excellent substrate for palladium-catalyzed cross-coupling reactions including Suzuki, Heck, Negishi, Sonogashira, and Buchwald–Hartwig amination. It can also be used for Grignard reagent preparation, metal–halogen exchange with organolithium reagents, and nucleophilic substitution reactions.

What drug discovery applications use 2-Chloro-indole-3-carbaldehyde 95%? +

The Indole ring system(s) in 2-Chloro-indole-3-carbaldehyde 95% is a privileged structure in medicinal chemistry, appearing in numerous FDA-approved drugs. This scaffold is commonly used in kinase inhibitor design, GPCR modulator development, and lead optimization programs. ChemContract supplies this building block for early-stage discovery through process-scale manufacturing.

How should I store 2-Chloro-indole-3-carbaldehyde 95%? +

Store at recommended temperature under inert atmosphere. Protect from air to prevent oxidation to the corresponding carboxylic acid. Store at recommended temperature in a well-sealed container. Protect from moisture and strong bases. Store at recommended temperature in a tightly sealed container. Some heterocyclic compounds are light-sensitive. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.

What is the CAS number of 2-Chloro-indole-3-carbaldehyde 95%? +

The CAS Registry Number for 2-Chloro-indole-3-carbaldehyde 95% is 5059-30-3. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.

Chemical analysis laboratory with HPLC instruments for purity and impurity testing Custom chemical synthesis reaction setup for pharmaceutical intermediate production

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