Frequently Asked
Common questions about 2-chloro-4-pyridinecarbonitrile
What is 2-chloro-4-pyridinecarbonitrile used for?
2-chloro-4-pyridinecarbonitrile is a chloro-substituted intermediate widely used in nucleophilic displacement reactions used primarily in the pharmaceutical and agrochemical industries. Key applications include nucleophilic aromatic substitution (snar) for ether and amine formation and core scaffold in kinase inhibitor design for oncology therapeutics.
Where can I buy 2-chloro-4-pyridinecarbonitrile in the USA?
ChemContract Research is a trusted USA-based supplier of 2-chloro-4-pyridinecarbonitrile. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.
What purity levels are available for 2-chloro-4-pyridinecarbonitrile?
ChemContract Research supplies 2-chloro-4-pyridinecarbonitrile in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.
Can ChemContract synthesize 2-chloro-4-pyridinecarbonitrile in custom quantities?
Yes. ChemContract Research offers custom synthesis services for 2-chloro-4-pyridinecarbonitrile from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.
What drug discovery applications use 2-chloro-4-pyridinecarbonitrile?
The Pyridine ring system(s) in 2-chloro-4-pyridinecarbonitrile is a privileged structure in medicinal chemistry, appearing in numerous FDA-approved drugs. This scaffold is commonly used in kinase inhibitor design, GPCR modulator development, and lead optimization programs. ChemContract supplies this building block for early-stage discovery through process-scale manufacturing.
What coupling reactions can I run with 2-chloro-4-pyridinecarbonitrile?
As a chlorinated compound, 2-chloro-4-pyridinecarbonitrile is an excellent substrate for palladium-catalyzed cross-coupling reactions including Suzuki, Heck, Negishi, Sonogashira, and Buchwald–Hartwig amination. It can also be used for Grignard reagent preparation, metal–halogen exchange with organolithium reagents, and nucleophilic substitution reactions.
How should I store 2-chloro-4-pyridinecarbonitrile?
Store at recommended temperature in a well-sealed container. Protect from moisture and strong bases. Store at recommended temperature in a tightly sealed container. Some heterocyclic compounds are light-sensitive. Store in a cool, dry, well-ventilated area. Keep tightly sealed and away from acids and strong bases. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.
What is the CAS number of 2-chloro-4-pyridinecarbonitrile?
The CAS Registry Number for 2-chloro-4-pyridinecarbonitrile is 33252-30-1. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.
