CAS 848499-31-0 · Brominated Compound · 3 functional traits · cGMP compliant · Ships from USA in 2-3 days
2-Bromothiazole-5-carboxamide (CAS Number: 848499-31-0) is a bromo-substituted intermediate prized for its reactivity in metal-catalyzed coupling featuring a Thiazole ring. ChemContract Research supplies this moderate-complexity compound in high purity from our Huntington Beach, California facility, ensuring consistent quality and reliable domestic delivery throughout the United States.
Aryl and alkyl bromides occupy a "Goldilocks zone" in cross-coupling — more reactive than chlorides yet more stable than iodides — making them the most commonly used coupling partners in process chemistry. Heterocyclic rings appear in approximately 85% of all biologically active compounds. The nitrogen, oxygen, or sulfur heteroatom modulates electron density, hydrogen bonding, and aqueous solubility. The amide bond is the single most common functional group in pharmaceutical compounds — its partial double-bond character provides both rigidity and hydrogen-bonding capability essential for target engagement.
Primary applications include grignard reagent preparation via magnesium insertion into c–br bond and core scaffold in kinase inhibitor design for oncology therapeutics. This compound serves researchers and manufacturers across the pharmaceutical, fine chemical, agrochemical sectors. Whether you require 2-Bromothiazole-5-carboxamide for early-stage research, process development, or commercial-scale production, ChemContract Research offers flexible ordering from milligram to multi-kilogram quantities with custom synthesis options and full batch documentation including Certificates of Analysis (CoA) and Safety Data Sheets.
How 2-Bromothiazole-5-carboxamide is used across pharmaceutical and fine chemical sectors
Grignard reagent preparation via magnesium insertion into C–Br bond
Core scaffold in kinase inhibitor design for oncology therapeutics
Peptide bond mimetic for peptidomimetic drug design
Palladium-catalyzed Suzuki, Heck, and Negishi cross-coupling
GPCR modulator development for CNS and cardiovascular indications
Weinreb amide substrate for selective aldehyde or ketone synthesis
Detailed specifications for this brominated compound, including purity, molecular weight, and analytical data are available upon request. Every batch from ChemContract Research includes:
Some brominated compounds may be lachrymatory or skin irritants. Handle in a fume hood with appropriate PPE. Handle with standard laboratory precautions. Some heterocycles may be hygroscopic or irritating. Use adequate ventilation. Handle with standard laboratory precautions. Consult the SDS for compound-specific hazards.
Store at room temperature in a tightly sealed, light-resistant container. Some bromo compounds require refrigeration. Store at recommended temperature in a tightly sealed container. Some heterocyclic compounds are light-sensitive. Store at room temperature or as specified. Keep tightly sealed and protect from moisture.
Aryl and alkyl bromides like 2-Bromothiazole-5-carboxamide are optimized for cross-coupling. We verify halide integrity and provide Pd-catalyst compatibility data on request.
Every batch of 2-Bromothiazole-5-carboxamide is produced under cGMP conditions with full CoA documentation, HPLC purity verification, and lot traceability.
Ship from our Huntington Beach, CA facility with 2-3 business day domestic delivery. No import delays, no customs fees, no tariff surprises.
Need a specific grade, quantity, or derivative of 2-Bromothiazole-5-carboxamide? Our team of PhD chemists can develop custom synthesis solutions for your exact requirements.
Common questions about 2-Bromothiazole-5-carboxamide
2-Bromothiazole-5-carboxamide is a bromo-substituted intermediate prized for its reactivity in metal-catalyzed coupling used primarily in the pharmaceutical and fine chemical industries. Key applications include grignard reagent preparation via magnesium insertion into c–br bond and core scaffold in kinase inhibitor design for oncology therapeutics.
ChemContract Research is a trusted USA-based supplier of 2-Bromothiazole-5-carboxamide. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.
ChemContract Research supplies 2-Bromothiazole-5-carboxamide in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.
Yes. ChemContract Research offers custom synthesis services for 2-Bromothiazole-5-carboxamide from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.
As a brominated compound, 2-Bromothiazole-5-carboxamide is an excellent substrate for palladium-catalyzed cross-coupling reactions including Suzuki, Heck, Negishi, Sonogashira, and Buchwald–Hartwig amination. It can also be used for Grignard reagent preparation, metal–halogen exchange with organolithium reagents, and nucleophilic substitution reactions.
The Thiazole ring system(s) in 2-Bromothiazole-5-carboxamide is a privileged structure in medicinal chemistry, appearing in numerous FDA-approved drugs. This scaffold is commonly used in kinase inhibitor design, GPCR modulator development, and lead optimization programs. ChemContract supplies this building block for early-stage discovery through process-scale manufacturing.
Store at room temperature in a tightly sealed, light-resistant container. Some bromo compounds require refrigeration. Store at recommended temperature in a tightly sealed container. Some heterocyclic compounds are light-sensitive. Store at room temperature or as specified. Keep tightly sealed and protect from moisture. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.
The CAS Registry Number for 2-Bromothiazole-5-carboxamide is 848499-31-0. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.
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