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2-Bromophenylhydrazinehydrochloride

CAS 50709-33-6 · Hydrazine Derivative · 3 functional traits · cGMP compliant · Ships from USA in 2-3 days

Hydrazine Derivative

2-Bromophenylhydrazinehydrochloride

Halogenated PharmaceuticalAgrochemicalFine ChemicalAnalytical ChemistryResearchFormulation
CAS Number 50709-33-6
Category Hydrazine Derivative · Brominated Compound
Origin USA
Compliance cGMP

Questions? Contact our chemistry team:

chemistry@chem-contract.com | +1 (714) 732-8549
In stock — typically ships within 2-3 business days

About 2-Bromophenylhydrazinehydrochloride

2-Bromophenylhydrazinehydrochloride (CAS Number: 50709-33-6) is a hydrazine-containing compound used as a versatile nitrogen nucleophile featuring a Benzene ring. ChemContract Research supplies this moderate-complexity compound in high purity from our Huntington Beach, California facility, ensuring consistent quality and reliable domestic delivery throughout the United States. Supplied as the hydrochloride salt form for enhanced stability and handling.

The N–N bond in hydrazines provides unique reactivity for heterocycle formation and is a key motif in several FDA-approved drugs including celecoxib and crizotinib analogs. Aryl and alkyl bromides occupy a "Goldilocks zone" in cross-coupling — more reactive than chlorides yet more stable than iodides — making them the most commonly used coupling partners in process chemistry. Hydrochloride is the most common salt form for basic drug substances — approximately half of all salt-form drugs on the market are HCl salts, valued for their crystallinity and aqueous solubility.

Primary applications include synthesis of pyrazole and pyridazine heterocycles from 1,3-diketones and grignard reagent preparation via magnesium insertion into c–br bond. This compound serves researchers and manufacturers across the pharmaceutical, agrochemical, fine chemical sectors. Whether you require 2-Bromophenylhydrazinehydrochloride for early-stage research, process development, or commercial-scale production, ChemContract Research offers flexible ordering from milligram to multi-kilogram quantities with custom synthesis options and full batch documentation including Certificates of Analysis (CoA) and Safety Data Sheets.

Ring Systems: Benzene
Functional Groups: Bromine (C–Br)Chlorine (C–Cl)
Salt Form: Hydrochloride

Hydrazine Derivative Applications & Target Industries

How 2-Bromophenylhydrazinehydrochloride is used across pharmaceutical and agrochemical sectors

01

Synthesis of pyrazole and pyridazine heterocycles from 1,3-diketones

02

Grignard reagent preparation via magnesium insertion into C–Br bond

03

Improved handling characteristics versus the free base form

04

Formation of hydrazones as carbonyl protecting groups and analytical probes

05

Palladium-catalyzed Suzuki, Heck, and Negishi cross-coupling

06

Direct formulation excipient in oral solid dosage forms

Target Industries: PharmaceuticalAgrochemicalFine ChemicalAnalytical ChemistryResearchFormulation

2-Bromophenylhydrazinehydrochloride Specifications

Detailed specifications for this hydrazine derivative, including purity, molecular weight, and analytical data are available upon request. Every batch from ChemContract Research includes:

  • Certificate of Analysis (CoA) with purity verification
  • HPLC, NMR, and/or mass spectrometry characterization data
  • Material Safety Data Sheet (MSDS/SDS)
  • Batch-specific documentation and lot traceability
  • Custom analytical testing available on request
Request Full Specifications

Quick Reference

Compound Name 2-Bromophenylhydrazinehydrochloride
Type Hydrazine Derivative
Category Hydrazine Derivative · Brominated Compound
Purity ≥95% (custom grades available)
Salt Form Hydrochloride
Complexity Moderate (2 functional groups, 1 ring)
Compliance cGMP
Packaging mg to kg scale

Storage & Handling for Hydrazine Derivatives

Handling Guidelines

Hydrazine derivatives may be toxic and potentially sensitizing. Always work in a well-ventilated fume hood with chemical-resistant gloves, safety goggles, and a lab coat. Some brominated compounds may be lachrymatory or skin irritants. Handle in a fume hood with appropriate PPE. Handle with standard precautions. Hydrochloride salts are generally more stable than free bases.

Storage Conditions

Store refrigerated (2–8 °C) in a tightly sealed container. Protect from light, heat, and oxidizing agents. Store at room temperature in a tightly sealed, light-resistant container. Some bromo compounds require refrigeration. Store at room temperature in a tightly sealed container. Protect from humidity.

Why Buy 2-Bromophenylhydrazinehydrochloride From ChemContract?

Quality Assured

Every batch of 2-Bromophenylhydrazinehydrochloride is produced under cGMP conditions with full CoA documentation, HPLC purity verification, and lot traceability.

Fast USA Shipping

Ship from our Huntington Beach, CA facility with 2-3 business day domestic delivery. No import delays, no customs fees, no tariff surprises.

Custom Synthesis

Need a specific grade, quantity, or derivative of 2-Bromophenylhydrazinehydrochloride? Our team of PhD chemists can develop custom synthesis solutions for your exact requirements.

Frequently Asked

Common questions about 2-Bromophenylhydrazinehydrochloride

What is 2-Bromophenylhydrazinehydrochloride used for? +

2-Bromophenylhydrazinehydrochloride is a hydrazine-containing compound used as a versatile nitrogen nucleophile used primarily in the pharmaceutical and agrochemical industries. Key applications include synthesis of pyrazole and pyridazine heterocycles from 1,3-diketones and grignard reagent preparation via magnesium insertion into c–br bond.

Where can I buy 2-Bromophenylhydrazinehydrochloride in the USA? +

ChemContract Research is a trusted USA-based supplier of 2-Bromophenylhydrazinehydrochloride. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.

What purity levels are available for 2-Bromophenylhydrazinehydrochloride? +

ChemContract Research supplies 2-Bromophenylhydrazinehydrochloride in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.

Can ChemContract synthesize 2-Bromophenylhydrazinehydrochloride in custom quantities? +

Yes. ChemContract Research offers custom synthesis services for 2-Bromophenylhydrazinehydrochloride from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.

Can I get 2-Bromophenylhydrazinehydrochloride in a different salt form or as the free base? +

Yes. ChemContract Research can supply 2-Bromophenylhydrazinehydrochloride as the free base or convert it to alternative salt forms including hydrochloride, mesylate, tosylate, fumarate, or other pharmaceutically acceptable counter-ions. Salt form selection impacts crystallinity, stability, and solubility — our chemistry team can advise on optimal salt selection for your application. Currently supplied as the Hydrochloride form.

What coupling reactions can I run with 2-Bromophenylhydrazinehydrochloride? +

As a brominated compound, 2-Bromophenylhydrazinehydrochloride is an excellent substrate for palladium-catalyzed cross-coupling reactions including Suzuki, Heck, Negishi, Sonogashira, and Buchwald–Hartwig amination. It can also be used for Grignard reagent preparation, metal–halogen exchange with organolithium reagents, and nucleophilic substitution reactions.

How should I store 2-Bromophenylhydrazinehydrochloride? +

Store refrigerated (2–8 °C) in a tightly sealed container. Protect from light, heat, and oxidizing agents. Store at room temperature in a tightly sealed, light-resistant container. Some bromo compounds require refrigeration. Store at room temperature in a tightly sealed container. Protect from humidity. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.

What is the CAS number of 2-Bromophenylhydrazinehydrochloride? +

The CAS Registry Number for 2-Bromophenylhydrazinehydrochloride is 50709-33-6. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.

Chemical analysis laboratory with HPLC instruments for purity and impurity testing Custom chemical synthesis reaction setup for pharmaceutical intermediate production

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