2-azaspiro[3.3]heptane-6-carboxylic acid trifluoroacetate

2-azaspiro[3.3]heptane-6-carboxylic acid trifluoroacetate is a fluorine-containing building block with enhanced metabolic stability used primarily in the pharmaceutical and diagnostic imaging industries. Key applications include metabolic blocking strategy — fluorine substitution to improve drug half-life and amide bond formation via edc/hobt or hatu coupling in peptide synthesis.

ChemContract Research is a trusted USA-based supplier of 2-azaspiro[3.3]heptane-6-carboxylic acid trifluoroacetate. We offer competitive pricing, fast domestic shipping from our Huntington Beach, California facility, and full quality documentation including Certificates of Analysis (CoA). Request a quote at chemistry@chem-contract.com or call +1 (714) 732-8549.

ChemContract Research supplies 2-azaspiro[3.3]heptane-6-carboxylic acid trifluoroacetate in multiple purity grades: ≥95% standard grade, ≥97% high-purity grade, and ≥99% ultra-high-purity grade depending on application requirements. We can also provide custom purity grades through our synthesis capabilities. Contact us for specific purity information and CoA documentation.

Yes. ChemContract Research offers custom synthesis services for 2-azaspiro[3.3]heptane-6-carboxylic acid trifluoroacetate from milligram to multi-kilogram scale. Our cGMP-compliant facilities and experienced chemists can accommodate custom specifications, packaging requirements, and delivery timelines. Contact our team to discuss your project.

The fluorine atom(s) in 2-azaspiro[3.3]heptane-6-carboxylic acid trifluoroacetate confer several advantages in drug design: increased metabolic stability due to the strong C–F bond (485 kJ/mol), enhanced lipophilicity for improved membrane permeability, and potential for favorable electrostatic interactions with biological targets. These properties make fluorinated compounds like 2-azaspiro[3.3]heptane-6-carboxylic acid trifluoroacetate valuable in pharmaceutical development.

Yes. ChemContract Research can supply 2-azaspiro[3.3]heptane-6-carboxylic acid trifluoroacetate as the free base or convert it to alternative salt forms including hydrochloride, mesylate, tosylate, fumarate, or other pharmaceutically acceptable counter-ions. Salt form selection impacts crystallinity, stability, and solubility — our chemistry team can advise on optimal salt selection for your application. Currently supplied as the Trifluoroacetate form.

Store at recommended temperature in a tightly sealed container. Protect from moisture, heat, and incompatible materials. Store at room temperature in a tightly sealed container. Protect from moisture and strong bases. Store at room temperature in a tightly sealed container away from heat and open flame. Store desiccated at –20 °C or as recommended. Protect from moisture to prevent deliquescence. Always consult the compound-specific Safety Data Sheet (SDS) provided with your order for detailed storage requirements. ChemContract Research includes handling and storage documentation with every shipment.

The CAS Registry Number for 2-azaspiro[3.3]heptane-6-carboxylic acid trifluoroacetate is 1523572-02-2. This unique identifier is used worldwide to reference this specific compound in chemical databases, regulatory filings, and scientific literature. ChemContract Research supplies this compound with full quality documentation. Contact us at chemistry@chem-contract.com for availability and pricing.